Details of CPPsite entry with Sequence RQIRIWFQNRRMRWRR |
Primary information | |
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PEPTIDE SEQUENCE | RQIRIWFQNRRMRWRR |
CPPsite ID | 2662, 1135, 1139, |
PEPTIDE NAME | PenArg, PenArg, 7Arg |
CHIRALITY | L, L, L |
LINEAR/CYCLIC | Linear, Linear, Linear |
SOURCE | Synthetic, Protein derived, Protein derived |
CATEGORY | Cationic and amphipathic, Amphipathic, Amphipathic |
SUB CELLULAR LOCALIZATION | Cytoplasm, Uneven distribution of peptide with accumulation in centrosmal area and in, Unknown |
N-TERMINAL MODIFICATION | NA, Conjugation with fluorescein, NA |
C-TERMINAL MODIFICATION | NA, Amidation, NA |
CHEMICAL MODIFICATION | NA, NA, NA |
UPTAKE EFFICIENCY | PenArg showed good transfection capability, High and comparable to (pAntp) (43-58), Unknown |
PROPOSED UPTAKE MECHANISM | Endocytosis, Energy-independent endocytic pathway, Unknown |
INVITRO/INVIVO | In vitro, In vitro, In vitro |
CELL LINE | HEK293T cells, PC-12 and V79 cells, Unknown |
In VIVO MODEL | NA, NA, NA |
CARGO | Nucleic acid (Plasmid DNA), Fluorophore (fluorescein), NA |
PMID | 22281502, 12849987, 18045726 |
PATENT | Unknown, Unknown, Unknown |
Tertiary Structure (Technique) | 2662 (PEPstrMOD), 1135 (PEPstrMOD), 1139 (PEPstrMOD), |