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Details of CPPsite entry with Sequence RQIRIWFQNRRMRWRR
Primary information
PEPTIDE SEQUENCERQIRIWFQNRRMRWRR
CPPsite ID 2662, 1135, 1139,
PEPTIDE NAMEPenArg, PenArg, 7Arg
CHIRALITYL, L, L
LINEAR/CYCLICLinear, Linear, Linear
SOURCESynthetic, Protein derived, Protein derived
CATEGORYCationic and amphipathic, Amphipathic, Amphipathic
SUB CELLULAR LOCALIZATIONCytoplasm, Uneven distribution of peptide with accumulation in centrosmal area and in, Unknown
N-TERMINAL MODIFICATIONNA, Conjugation with fluorescein, NA
C-TERMINAL MODIFICATIONNA, Amidation, NA
CHEMICAL MODIFICATIONNA, NA, NA
UPTAKE EFFICIENCYPenArg showed good transfection capability, High and comparable to (pAntp) (43-58), Unknown
PROPOSED UPTAKE MECHANISMEndocytosis, Energy-independent endocytic pathway, Unknown
INVITRO/INVIVOIn vitro, In vitro, In vitro
CELL LINEHEK293T cells, PC-12 and V79 cells, Unknown
In VIVO MODELNA, NA, NA
CARGONucleic acid (Plasmid DNA), Fluorophore (fluorescein), NA
PMID22281502, 12849987, 18045726
PATENTUnknown, Unknown, Unknown
Tertiary Structure
(Technique)
2662 (PEPstrMOD), 1135 (PEPstrMOD), 1139 (PEPstrMOD),