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This page gives details of CPPsite entry with ID 1135 |
| Primary information | |
|---|---|
| CPPsite ID | 1135 |
| PEPTIDE SEQUENCE | RQIRIWFQNRRMRWRR |
| PEPTIDE NAME | PenArg |
| CHIRALITY | L |
| LINEAR/CYCLIC | Linear |
| SOURCE | Protein derived |
| CATEGORY | Amphipathic |
| SUB CELLULAR LOCALIZATION | Uneven distribution of peptide with accumulation in centrosmal area and in |
| N-TERMINAL MODIFICATION | Conjugation with fluorescein |
| C-TERMINAL MODIFICATION | Amidation |
| UPTAKE EFFICIENCY | High and comparable to (pAntp) (43-58) |
| PROPOSED UPTAKE MECHANISM | Energy-independent endocytic pathway |
| INVITRO/INVIVO | In vitro |
| CELL LINE | PC-12 and V79 cells |
| CARGO | Fluorophore (fluorescein) |
| PMID | 12849987 |
| PATENT | Unknown |
| LENGTH | 16 |
| Secondary Structure | CCSSSCSSSCCSSSCC |
| SMILES | N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O |
| Tertiary Structure (Technique) | View in Jmol OR Download Structure (PEPstrMOD) |