Details of CPPsite entry with Sequence RQIKIWFPNRRMKWKK |
Primary information | |
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PEPTIDE SEQUENCE | RQIKIWFPNRRMKWKK |
CPPsite ID | 1093, 1132, |
PEPTIDE NAME | pAntpHD (Pro50), Penetratin (pAntp) (43-58) |
CHIRALITY | L, L |
LINEAR/CYCLIC | Linear, Linear |
SOURCE | Protein derived, Protein derived |
CATEGORY | Unknown, Amphipathic |
SUB CELLULAR LOCALIZATION | Cytoplasm, Cytosol and nucleus, nucleoi |
N-TERMINAL MODIFICATION | Biotinylation, Conjugation with fluorescein |
C-TERMINAL MODIFICATION | Amidation, Amidation |
CHEMICAL MODIFICATION | NA, NA |
UPTAKE EFFICIENCY | High, comparbale to (pAntp) (43-58), Unknown |
PROPOSED UPTAKE MECHANISM | Non-receptor mdiated endocytic pathway, Non-endocytic pathway |
INVITRO/INVIVO | In vitro, In vitro |
CELL LINE | Cortical striatal cells, HaCat/ A549 cells |
In VIVO MODEL | NA, NA |
CARGO | Biotin, Fluorophore (fluorescein) |
PMID | 8663410, 10784032 |
PATENT | Unknown, Unknown |
Tertiary Structure (Technique) | 1093 (PEPstrMOD), 1132 (PEPstrMOD), |