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Details of CPPsite entry with Sequence RQIKIWFPNRRMKWKK
Primary information
PEPTIDE SEQUENCERQIKIWFPNRRMKWKK
CPPsite ID 1093, 1132,
PEPTIDE NAMEpAntpHD (Pro50), Penetratin (pAntp) (43-58)
CHIRALITYL, L
LINEAR/CYCLICLinear, Linear
SOURCEProtein derived, Protein derived
CATEGORYUnknown, Amphipathic
SUB CELLULAR LOCALIZATIONCytoplasm, Cytosol and nucleus, nucleoi
N-TERMINAL MODIFICATIONBiotinylation, Conjugation with fluorescein
C-TERMINAL MODIFICATIONAmidation, Amidation
CHEMICAL MODIFICATIONNA, NA
UPTAKE EFFICIENCYHigh, comparbale to (pAntp) (43-58), Unknown
PROPOSED UPTAKE MECHANISMNon-receptor mdiated endocytic pathway, Non-endocytic pathway
INVITRO/INVIVOIn vitro, In vitro
CELL LINECortical striatal cells, HaCat/ A549 cells
In VIVO MODELNA, NA
CARGOBiotin, Fluorophore (fluorescein)
PMID8663410, 10784032
PATENTUnknown, Unknown
Tertiary Structure
(Technique)
1093 (PEPstrMOD), 1132 (PEPstrMOD),