Welcome to Entry Card of Peptide


This page gives details of CPPsite entry with ID 1132
Primary information
CPPsite ID1132
PEPTIDE SEQUENCERQIKIWFPNRRMKWKK
PEPTIDE NAMEPenetratin (pAntp) (43-58)
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYAmphipathic
SUB CELLULAR LOCALIZATIONCytosol and nucleus, nucleoi
N-TERMINAL MODIFICATIONConjugation with fluorescein
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYUnknown
PROPOSED UPTAKE MECHANISMNon-endocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEHaCat/ A549 cells
CARGOFluorophore (fluorescein)
PMID10784032
PATENTUnknown
LENGTH16
Secondary StructureCCCCSSSSCSGGGTCC
SMILESN[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C=O
Tertiary Structure
(Technique)
View in Jmol  OR Download Structure
 (PEPstrMOD)