This page gives details of CPPsite entry with ID 1132 |
Primary information | |
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CPPsite ID | 1132 |
PEPTIDE SEQUENCE | RQIKIWFPNRRMKWKK |
PEPTIDE NAME | Penetratin (pAntp) (43-58) |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Protein derived |
CATEGORY | Amphipathic |
SUB CELLULAR LOCALIZATION | Cytosol and nucleus, nucleoi |
N-TERMINAL MODIFICATION | Conjugation with fluorescein |
C-TERMINAL MODIFICATION | Amidation |
UPTAKE EFFICIENCY | Unknown |
PROPOSED UPTAKE MECHANISM | Non-endocytic pathway |
INVITRO/INVIVO | In vitro |
CELL LINE | HaCat/ A549 cells |
CARGO | Fluorophore (fluorescein) |
PMID | 10784032 |
PATENT | Unknown |
LENGTH | 16 |
Secondary Structure | CCCCSSSSCSGGGTCC |
SMILES | N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C=O |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (PEPstrMOD) |