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Details of CPPsite entry with Sequence RKKRRRESRKKRRRES
Primary information
PEPTIDE SEQUENCERKKRRRESRKKRRRES
CPPsite ID 1206,
PEPTIDE NAMEDPV3
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYUnknown
SUB CELLULAR LOCALIZATIONCytoplasm
N-TERMINAL MODIFICATIONCys addition
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYHigher than other DPVs and Tat (48-60)
PROPOSED UPTAKE MECHANISMEnergy-dependent endocytic process involving cell membrane lipid rafts
INVITRO/INVIVOIn vitro
CELL LINEHeLa, HCT116, HL-60, K562, Molt4, NIH-3T3 and primary hepatocyte cultures
CARGOProtein (PO and IgG)
PMID15859953
PATENTUnknown
Tertiary Structure
(Technique)		1206 (PEPstrMOD),