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Details of CPPsite entry with Sequence Nbtg-Nbtg-Nspe-Nbtg-Nbtg-Nspe-Nbtg-Nbtg-Nspe-Nbtg-Nbtg-Nspe |
| Primary information | |
|---|---|
| PEPTIDE SEQUENCE | Nbtg-Nbtg-Nspe-Nbtg-Nbtg-Nspe-Nbtg-Nbtg-Nspe-Nbtg-Nbtg-Nspe |
| CPPsite ID | 2756, |
| PEPTIDE NAME | Guanidylated variants |
| CHIRALITY | Modified |
| LINEAR/CYCLIC | Linear |
| SOURCE | Synthetic |
| CATEGORY | Cationic and amphipathic |
| SUB CELLULAR LOCALIZATION | Punctated cytoplasmic and nucleus |
| N-TERMINAL MODIFICATION | Conjugation with 5(6)-Carboxyfluorescein |
| C-TERMINAL MODIFICATION | Amidation |
| CHEMICAL MODIFICATION | Peptoids (poly-N-substituted glycines) |
| UPTAKE EFFICIENCY | High (Compare to Polyguanidine comparator 1) |
| PROPOSED UPTAKE MECHANISM | Probably Energy-dependent Internalization |
| INVITRO/INVIVO | In vitro |
| CELL LINE | MCF-7 cells |
| CARGO | Fluorophore [5(6)-Carboxyfluorescein (CF)] |
| PMID | 22828784 |
| PATENT | Unknown |
| Tertiary Structure (Technique) | Not Predicted), |