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This page gives details of CPPsite entry with ID 2756
Primary information
CPPsite ID2756
PEPTIDE SEQUENCENbtg-Nbtg-Nspe-Nbtg-Nbtg-Nspe-Nbtg-Nbtg-Nspe-Nbtg-Nbtg-Nspe
PEPTIDE NAMEGuanidylated variants
CHIRALITYModified
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic and amphipathic
SUB CELLULAR LOCALIZATIONPunctated cytoplasmic and nucleus
N-TERMINAL MODIFICATIONConjugation with 5(6)-Carboxyfluorescein
C-TERMINAL MODIFICATIONAmidation
CHEMICAL MODIFICATIONPeptoids (poly-N-substituted glycines)
UPTAKE EFFICIENCYHigh (Compare to Polyguanidine comparator 1)
PROPOSED UPTAKE MECHANISMProbably Energy-dependent Internalization
INVITRO/INVIVOIn vitro
CELL LINEMCF-7 cells
CARGOFluorophore [5(6)-Carboxyfluorescein (CF)]
PMID22828784
PATENTUnknown
LENGTH12
Secondary StructureNA
SMILESNA
3-D StructureNot Predicted