Details of CPPsite entry with Sequence NYRWRCKNQN |
Primary information | |
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PEPTIDE SEQUENCE | NYRWRCKNQN |
CPPsite ID | 2022, 2953, |
PEPTIDE NAME | ECP(32-41), CPPecp |
CHIRALITY | L, L |
LINEAR/CYCLIC | Linear, Linear |
SOURCE | Protein derived, Protein derived |
CATEGORY | Cationic, NA |
SUB CELLULAR LOCALIZATION | Cytoplasm and Nucleus, NA |
N-TERMINAL MODIFICATION | Free, Conjugation with FITC |
C-TERMINAL MODIFICATION | Free, Free |
CHEMICAL MODIFICATION | NA, NA |
UPTAKE EFFICIENCY | NA, NA |
PROPOSED UPTAKE MECHANISM | Lipid raft dependent macropinocytosis, NA |
INVITRO/INVIVO | In vitro and in vivo, In vitro |
CELL LINE | Beas-2B, A549, Caco-2 cells, AGS cells, CHO-K1, CHO pgsD677 cells, CHO-pgsA745 cells, CT-26 cells |
In VIVO MODEL | Female Sprague-Dawley rats, Female Balb/c mice |
CARGO | Fluorophore (FITC), Protein (eGFP) and Peptide (KLA), Nanoparticle |
PMID | 23469189, 26064887 |
PATENT | Unknown, Unknown |
Tertiary Structure (Technique) | 2022 (PEPstrMOD), 2953 (PEPstrMOD), |