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This page gives details of CPPsite entry with ID 2022
Primary information
CPPsite ID2022
PEPTIDE SEQUENCENYRWRCKNQN
PEPTIDE NAMEECP(32-41)
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm and Nucleus
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONFree
PROPOSED UPTAKE MECHANISMLipid raft dependent macropinocytosis
INVITRO/INVIVOIn vitro and in vivo
CELL LINEBeas-2B, A549, Caco-2 cells, AGS cells, CHO-K1, CHO pgsD677 cells, CHO-pgsA745 cells
In VIVO MODELFemale Sprague-Dawley rats
CARGOFluorophore (FITC), Protein (eGFP) and Peptide (KLA)
PMID23469189
PATENTUnknown
LENGTH10
Secondary StructureCCCSSSSSCC
SMILESN[C@@H](CC(=O)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C=O
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)