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Details of CPPsite entry with Sequence GRKKRRQRRRPWQ
Primary information
PEPTIDE SEQUENCEGRKKRRQRRRPWQ
CPPsite ID 1137, 1138,
PEPTIDE NAMETatP59W, TatP59W
CHIRALITYL, L
LINEAR/CYCLICLinear, Linear
SOURCEProtein derived, Protein derived
CATEGORYCationic, Cationic
SUB CELLULAR LOCALIZATIONCytoplasm and nucleus, Cytoplasm and nucleus
N-TERMINAL MODIFICATIONConjugation with fluorescein, Conjugation with fluorescein
C-TERMINAL MODIFICATIONAmidation, Amidation
CHEMICAL MODIFICATIONNA, NA
UPTAKE EFFICIENCYComparable to that of (pAntp) (43-58), Comparable to that of (pAntp) (43-58)
PROPOSED UPTAKE MECHANISMEndocytic pathway, Non-endocytic pathway
INVITRO/INVIVOIn vitro, In vitro
CELL LINEPC-12 cells, V79 cells
In VIVO MODELNA, NA
CARGOFluorophore (fluorescein), Fluorophore (fluorescein)
PMID12849987, 12849987
PATENTUnknown, Unknown
Tertiary Structure
(Technique)
1137 (PEPstrMOD), 1138 (PEPstrMOD),