Details of CPPsite entry with Sequence GRKKRRQRRRPWQ |
Primary information | |
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PEPTIDE SEQUENCE | GRKKRRQRRRPWQ |
CPPsite ID | 1137, 1138, |
PEPTIDE NAME | TatP59W, TatP59W |
CHIRALITY | L, L |
LINEAR/CYCLIC | Linear, Linear |
SOURCE | Protein derived, Protein derived |
CATEGORY | Cationic, Cationic |
SUB CELLULAR LOCALIZATION | Cytoplasm and nucleus, Cytoplasm and nucleus |
N-TERMINAL MODIFICATION | Conjugation with fluorescein, Conjugation with fluorescein |
C-TERMINAL MODIFICATION | Amidation, Amidation |
CHEMICAL MODIFICATION | NA, NA |
UPTAKE EFFICIENCY | Comparable to that of (pAntp) (43-58), Comparable to that of (pAntp) (43-58) |
PROPOSED UPTAKE MECHANISM | Endocytic pathway, Non-endocytic pathway |
INVITRO/INVIVO | In vitro, In vitro |
CELL LINE | PC-12 cells, V79 cells |
In VIVO MODEL | NA, NA |
CARGO | Fluorophore (fluorescein), Fluorophore (fluorescein) |
PMID | 12849987, 12849987 |
PATENT | Unknown, Unknown |
Tertiary Structure (Technique) | 1137 (PEPstrMOD), 1138 (PEPstrMOD), |