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This page gives details of CPPsite entry with ID 1137
Primary information
CPPsite ID1137
PEPTIDE SEQUENCEGRKKRRQRRRPWQ
PEPTIDE NAMETatP59W
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm and nucleus
N-TERMINAL MODIFICATIONConjugation with fluorescein
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYComparable to that of (pAntp) (43-58)
PROPOSED UPTAKE MECHANISMEndocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEPC-12 cells
CARGOFluorophore (fluorescein)
PMID12849987
PATENTUnknown
LENGTH13
Secondary StructureCTHHHHCSSSCCC
SMILESNCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(=O)N)C=O
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)