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Details of CPPsite entry with Sequence GGVCPKILKKCRRDSDCPGACICRGNGYCGSGSD
Primary information
PEPTIDE SEQUENCEGGVCPKILKKCRRDSDCPGACICRGNGYCGSGSD
CPPsite ID 2452, 2458, 1795,
PEPTIDE NAMEMCoTI-II, MCoTI-M6, MCoTI-II(MCo)
CHIRALITYL, L, L
LINEAR/CYCLICCyclic, Cyclic, Cyclic
SOURCESynthetic, Synthetic, Protein derived
CATEGORYCationic, Cationic, Unknown
SUB CELLULAR LOCALIZATIONNA, NA, Endosomal compartments (vesicles)
N-TERMINAL MODIFICATIONConjugation with Alexa Flour 488, Conjugation with Alexa Flour 488, Conjugation with Alexa-488
C-TERMINAL MODIFICATIONFree, Free, Cyclization
CHEMICAL MODIFICATIONNA, NA, NA
UPTAKE EFFICIENCYHigher uptake efficiency, High (compared to native MCoTI-II), Unknown
PROPOSED UPTAKE MECHANISMMacropinocytosis, endocytosis, Macropinocytosis, endocytosis, Endocytic pathway
INVITRO/INVIVOIn vitro, In vitro, In vitro
CELL LINEHeLa, HeLa, RAW 264.7 and MCF-7
In VIVO MODELNA, NA, NA
CARGOFluorophore (Alexa Fluor 488), Fluorophore (Alexa Fluor 488), Fluorophore (Alexa-488)
PMID24985034, 24985034, 21873420
PATENTUnknown, Unknown, Unknown
Tertiary Structure
(Technique)		2452 (I-TASSER), 2458 (I-TASSER), 1795 (I-TASSER),