Welcome to Entry Card of Peptide


This page gives details of CPPsite entry with ID 2458
Primary information
CPPsite ID2458
PEPTIDE SEQUENCEGGVCPKILKKCRRDSDCPGACICRGNGYCGSGSD
PEPTIDE NAMEMCoTI-M6
CHIRALITYL
LINEAR/CYCLICCyclic
SOURCESynthetic
CATEGORYCationic
N-TERMINAL MODIFICATIONConjugation with Alexa Flour 488
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYHigh (compared to native MCoTI-II)
PROPOSED UPTAKE MECHANISMMacropinocytosis, endocytosis
INVITRO/INVIVOIn vitro
CELL LINEHeLa
CARGOFluorophore (Alexa Fluor 488)
PMID24985034
PATENTUnknown
LENGTH34
Secondary StructureCCBCCSCCCBCSSGGGSCSSCEEETTTEEECSBC
SMILESNCC(=O)NCC(=O)N[C@H](C(=O)N[C@@H]1C(=O)N2[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H]4C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H]5C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C=O)CC(=O)O)CO)CO)CS[S@@](SC3)(C4)SC5)Cc3ccc(cc3)O)CC(=O)N)CCCNC(=N)N)[C@H](CC)C)CSSC1)C)CCC)CC(=O)O)CO)CC(=O)O)CCCNC(=N)N)CCCN
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (Homology based)