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Details of CPPsite entry with Sequence CRGDK
Primary information
PEPTIDE SEQUENCECRGDK
CPPsite ID 2098,
PEPTIDE NAMECRGDK
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
SUB CELLULAR LOCALIZATIONLysosomes and Cytoplasm
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYNeuropilin-1 mediated
INVITRO/INVIVOIn vitro and in vivo
CELL LINEhuman metastatic breast cancer cell line MDA-MB- 231, the aggressive human metastatic prostate cancer cell line PC3
In VIVO MODELNude mice bearing MDA-MB-231 tumors
CARGOSmall molecule drug (Doxorubicin), DSPE- PEG2000
PMID23634882
PATENTUnknown
Tertiary Structure
(Technique)
2098 (PEPstrMOD),