Details of CPPsite entry with Sequence CRGDK |
Primary information | |
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PEPTIDE SEQUENCE | CRGDK |
CPPsite ID | 2098, |
PEPTIDE NAME | CRGDK |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Synthetic |
SUB CELLULAR LOCALIZATION | Lysosomes and Cytoplasm |
N-TERMINAL MODIFICATION | Free |
C-TERMINAL MODIFICATION | Free |
UPTAKE EFFICIENCY | Neuropilin-1 mediated |
INVITRO/INVIVO | In vitro and in vivo |
CELL LINE | human metastatic breast cancer cell line MDA-MB- 231, the aggressive human metastatic prostate cancer cell line PC3 |
In VIVO MODEL | Nude mice bearing MDA-MB-231 tumors |
CARGO | Small molecule drug (Doxorubicin), DSPE- PEG2000 |
PMID | 23634882 |
PATENT | Unknown |
Tertiary Structure (Technique) | 2098 (PEPstrMOD), |