This page gives details of CPPsite entry with ID 2098 |
Primary information | |
---|---|
CPPsite ID | 2098 |
PEPTIDE SEQUENCE | CRGDK |
PEPTIDE NAME | CRGDK |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Synthetic |
SUB CELLULAR LOCALIZATION | Lysosomes and Cytoplasm |
N-TERMINAL MODIFICATION | Free |
C-TERMINAL MODIFICATION | Free |
UPTAKE EFFICIENCY | Neuropilin-1 mediated |
INVITRO/INVIVO | In vitro and in vivo |
CELL LINE | human metastatic breast cancer cell line MDA-MB- 231, the aggressive human metastatic prostate cancer cell line PC3 |
In VIVO MODEL | Nude mice bearing MDA-MB-231 tumors |
CARGO | Small molecule drug (Doxorubicin), DSPE- PEG2000 |
PMID | 23634882 |
PATENT | Unknown |
LENGTH | 5 |
Secondary Structure | CCCCC |
SMILES | N[C@@H](CS)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCC[NH3])C=O |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (PEPstrMOD) |