ApoCanD

#	Name/ID	Cell Line/Tumor sample	Tissue of Origin	Reference ID	cDNA change	Protein change	Source	FATHMM Prediction	PolyPhen2 Prediction
1	639V	Cell Line	URINARY TRACT	NP_001057	c.851T>C	p.M284T	CCLE	PASSENGER/OTHER	Benign
2	A704	Cell Line	KIDNEY	NP_001057	c.345C>A	p.N115K	CCLE	PASSENGER/OTHER	Probably Damaging
3	AN3CA	Cell Line	ENDOMETRIUM	NP_001057	c.673C>A	p.Q225K	CCLE	PASSENGER/OTHER	Benign
4	DV90	Cell Line	LUNG	NP_001057	c.1159G>A	p.V387I	CCLE	PASSENGER/OTHER	Probably Damaging
5	HCC2218	Cell Line	BREAST	NP_001057	c.1109C>T	p.S370F	CCLE	PASSENGER/OTHER	Possibly Damaging
6	HCC33	Cell Line	LUNG	NP_001057	c.329G>T	p.C110F	CCLE	CANCER	Probably Damaging
7	HCC33	Cell Line	LUNG	NP_001057	c.331A>T	p.T111S	CCLE	PASSENGER/OTHER	Probably Damaging
8	HCC827	Cell Line	LUNG	NP_001057	c.902C>G	p.P301R	CCLE	PASSENGER/OTHER	Benign
9	HEC1A	Cell Line	ENDOMETRIUM	NP_001057	c.255G>T	p.Q85H	CCLE	PASSENGER/OTHER	Probably Damaging
10	HEC1B	Cell Line	ENDOMETRIUM	NP_001057	c.255G>T	p.Q85H	CCLE	PASSENGER/OTHER	Probably Damaging
11	HEC251	Cell Line	ENDOMETRIUM	NP_001057	c.130G>T	p.E44*	CCLE	NP	NP
12	HPBALL	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_001057	c.1153G>A	p.V385M	CCLE	PASSENGER/OTHER	Probably Damaging
13	HT	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_001057	c.950A>C	p.Q317P	CCLE	PASSENGER/OTHER	Probably Damaging
14	HT55	Cell Line	LARGE INTESTINE	NP_001057	c.1337_1338AG>TT	p.E446V	CCLE	PASSENGER/OTHER	Probably Damaging
15	KMBC2	Cell Line	URINARY TRACT	NP_001057	c.396G>A	p.E132E	CCLE	NP	NP
16	MDAMB231	Cell Line	BREAST	NP_001057	c.420G>C	p.L140L	CCLE	NP	NP
17	MEC1	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_001057	c.1264C>T	p.P422S	CCLE	PASSENGER/OTHER	Probably Damaging
18	MFE319	Cell Line	ENDOMETRIUM	NP_001057	c.458G>A	p.G153E	CCLE	PASSENGER/OTHER	Probably Damaging
19	MKN7	Cell Line	STOMACH	NP_001057	c.1034G>A	p.R345Q	CCLE	PASSENGER/OTHER	Benign
20	NCIH1793	Cell Line	LUNG	NP_001057	c.1070G>T	p.G357V	CCLE	PASSENGER/OTHER	Possibly Damaging
21	RERFLCAD1	Cell Line	LUNG	NP_001057	c.770A>C	p.D257A	CCLE	PASSENGER/OTHER	Benign
22	SNU81	Cell Line	LARGE INTESTINE	NP_001057	c.130G>T	p.E44*	CCLE	NP	NP
23	TEN	Cell Line	ENDOMETRIUM	NP_001057	c.396G>A	p.E132E	CCLE	NP	NP
24	YAPC	Cell Line	PANCREAS	NP_001057	c.925C>G	p.R309G	CCLE	PASSENGER/OTHER	Benign
25	22T	Tumour	SKIN	ENST00000376259	c.1275G>A	p.K425K	COSMIC	NP	NP
26	587238	Tumour	LARGE INTESTINE	ENST00000376259	c.251C>T	p.T84I	COSMIC	NP	NP
27	587278	Tumour	LARGE INTESTINE	ENST00000376259	c.769G>A	p.D257N	COSMIC	NP	NP
28	ESO-085	Tumour	OESOPHAGUS	ENST00000376259	c.1150_1164del15	p.I384_C388delIVNVC	COSMIC	NP	NP
29	ESO-164	Tumour	OESOPHAGUS	ENST00000376259	c.1291C>T	p.R431W	COSMIC	NP	NP
30	GC8	Tumour	T STOMACH	ENST00000376259	c.587T>G	p.M196R	COSMIC	NP	NP
31	HCC30T	Tumour	LIVER	ENST00000376259	c.916G>A	p.D306N	COSMIC	NP	NP
32	HCC4T	Tumour	LIVER	ENST00000376259	c.641T>C	p.V214A	COSMIC	NP	NP
33	HN	Tumour	62854 UPPER AERODIGESTIVE TRACT	ENST00000376259	c.1239G>T	p.S413S	COSMIC	NP	NP
34	HX13T	Tumour	LIVER	ENST00000376259	c.641T>C	p.V214A	COSMIC	NP	NP
35	LUAD-CHTN-MAD06-00668	Tumour	LUNG	ENST00000376259	c.303C>A	p.S101R	COSMIC	NP	NP
36	LUAD-F00365	Tumour	LUNG	ENST00000376259	c.134A>T	p.Y45F	COSMIC	NP	NP
37	TCGA-05-4398-01	Tumour	LUNG	ENST00000376259	c.425A>T	p.K142M	COSMIC	NP	NP
38	TCGA-06-0126-01	Tumour	CENTRAL NERVOUS SYSTEM	ENST00000376259	c.664A>C	p.T222P	COSMIC	NP	NP
39	TCGA-21-1078-01	Tumour	LUNG	ENST00000376259	c.436G>C	p.G146R	COSMIC	NP	NP
40	TCGA-64-5775-01	Tumour	LUNG	ENST00000376259	c.147A>T	p.T49T	COSMIC	NP	NP
41	TCGA-95-7947-01	Tumour	LUNG	ENST00000376259	c.609G>T	p.T203T	COSMIC	NP	NP
42	TCGA-A5-A0VP-01	Tumour	ENDOMETRIUM	ENST00000376259	c.609G>A	p.T203T	COSMIC	NP	NP
43	TCGA-AA-3655-01	Tumour	LARGE INTESTINE	ENST00000376259	c.666A>G	p.T222T	COSMIC	NP	NP
44	TCGA-AA-3662-01	Tumour	LARGE INTESTINE	ENST00000376259	c.665C>A	p.T222K	COSMIC	NP	NP
45	TCGA-AP-A051-01	Tumour	ENDOMETRIUM	ENST00000376259	c.475G>A	p.V159M	COSMIC	NP	NP
46	TCGA-CK-5916-01	Tumour	LARGE INTESTINE	ENST00000376259	c.1371G>A	p.G457G	COSMIC	NP	NP
47	TCGA-CM-6171-01	Tumour	LARGE INTESTINE	ENST00000376259	c.783A>C	p.P261P	COSMIC	NP	NP
48	TCGA-CU-A0YN-01	Tumour	URINARY TRACT	ENST00000376259	c.637G>C	p.A213P	COSMIC	NP	NP
49	TCGA-D1-A15X-01	Tumour	ENDOMETRIUM	ENST00000376259	c.109G>A	p.G37R	COSMIC	NP	NP
50	TCGA-FD-A3N5-01	Tumour	URINARY TRACT	ENST00000376259	c.422G>A	p.R141H	COSMIC	NP	NP
51	YUKLAB	Tumour	SKIN	ENST00000376259	c.1215G>A	p.M405I	COSMIC	NP	NP
52	YUKLAB	Tumour	SKIN	ENST00000376259	c.1225G>C	p.D409H	COSMIC	NP	NP
53	A431	Cell Line	SKIN	ENST00000376259	c.781C>T	p.P261S	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
54	A704	Cell Line	KIDNEY	ENST00000376259	c.345C>A	p.N115K	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
55	AN3CA	Cell Line	ENDOMETRIUM	ENST00000376259	c.673C>A	p.Q225K	COSMIC	PASSENGER/OTHER	BENIGN
56	BXPC3	Cell Line	PANCREAS	ENST00000376259	c.603G>A	p.T201T	COSMIC	NP	NP
57	C3A	Cell Line	LIVER	ENST00000376259	c.820C>T	p.L274L	COSMIC	NP	NP
58	CTV1	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000376259	c.735delG	p.G246fs*19	COSMIC	NP	NP
59	EBC1	Cell Line	LUNG	ENST00000376259	c.1292G>A	p.R431Q	COSMIC	PASSENGER/OTHER	BENIGN
60	EJM	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000376259	c.271C>T	p.P91S	COSMIC	PASSENGER/OTHER	BENIGN
61	GRST	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000376259	c.787+8G>A	p.?	COSMIC	NP	NP
62	HCC2218	Cell Line	BREAST	ENST00000376259	c.1109C>T	p.S370F	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
63	HCC33	Cell Line	LUNG	ENST00000376259	c.1106-8C>A	p.?	COSMIC	NP	NP
64	HCC33	Cell Line	LUNG	ENST00000376259	c.329G>T	p.C110F	COSMIC	CANCER	PROBABLY DAMAGING
65	HCC33	Cell Line	LUNG	ENST00000376259	c.331A>T	p.T111S	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
66	HEC1	Cell Line	ENDOMETRIUM	ENST00000376259	c.255G>T	p.Q85H	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
67	HT55	Cell Line	LARGE_INTESTINE	ENST00000376259	c.1337A>T	p.E446V	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
68	HT55	Cell Line	LARGE_INTESTINE	ENST00000376259	c.1338G>T	p.E446D	COSMIC	PASSENGER/OTHER	BENIGN
69	ISTSL2	Cell Line	LUNG	ENST00000376259	c.545A>C	p.H182P	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
70	KY821	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000376259	c.204C>G	p.T68T	COSMIC	NP	NP
71	KYSE30	Cell Line	OESOPHAGUS	ENST00000376259	c.178+8C>T	p.?	COSMIC	NP	NP
72	MCC13	Cell Line	SKIN	ENST00000376259	c.774C>T	p.F258F	COSMIC	NP	NP
73	MDAMB231	Cell Line	BREAST	ENST00000376259	c.420G>C	p.L140L	COSMIC	NP	NP
74	MFE319	Cell Line	ENDOMETRIUM	ENST00000376259	c.458G>A	p.G153E	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
75	SNU407	Cell Line	LARGE_INTESTINE	ENST00000376259	c.1239G>A	p.S413S	COSMIC	NP	NP
76	SNU81	Cell Line	LARGE_INTESTINE	ENST00000376259	c.130G>T	p.E44*	COSMIC	NP	NP
77	SUDHL6	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000376259	c.395A>T	p.E132V	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
78	SW872	Cell Line	SOFT_TISSUE	ENST00000376259	c.1292G>A	p.R431Q	COSMIC	PASSENGER/OTHER	BENIGN
79	TMK1	Cell Line	STOMACH	ENST00000376259	c.922G>A	p.A308T	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
80	639V	Cell Line	URINARY TRACT	NP_001057	c.851T>C	p.M284T	CCLE	PASSENGER/OTHER	Benign
81	A704	Cell Line	KIDNEY	NP_001057	c.345C>A	p.N115K	CCLE	PASSENGER/OTHER	Probably Damaging
82	AN3CA	Cell Line	ENDOMETRIUM	NP_001057	c.673C>A	p.Q225K	CCLE	PASSENGER/OTHER	Benign
83	DV90	Cell Line	LUNG	NP_001057	c.1159G>A	p.V387I	CCLE	PASSENGER/OTHER	Probably Damaging
84	HCC2218	Cell Line	BREAST	NP_001057	c.1109C>T	p.S370F	CCLE	PASSENGER/OTHER	Possibly Damaging
85	HCC33	Cell Line	LUNG	NP_001057	c.329G>T	p.C110F	CCLE	CANCER	Probably Damaging
86	HCC33	Cell Line	LUNG	NP_001057	c.331A>T	p.T111S	CCLE	PASSENGER/OTHER	Probably Damaging
87	HCC827	Cell Line	LUNG	NP_001057	c.902C>G	p.P301R	CCLE	PASSENGER/OTHER	Benign
88	HEC1A	Cell Line	ENDOMETRIUM	NP_001057	c.255G>T	p.Q85H	CCLE	PASSENGER/OTHER	Probably Damaging
89	HEC1B	Cell Line	ENDOMETRIUM	NP_001057	c.255G>T	p.Q85H	CCLE	PASSENGER/OTHER	Probably Damaging
90	HEC251	Cell Line	ENDOMETRIUM	NP_001057	c.130G>T	p.E44*	CCLE	NP	NP
91	HPBALL	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_001057	c.1153G>A	p.V385M	CCLE	PASSENGER/OTHER	Probably Damaging
92	HT	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_001057	c.950A>C	p.Q317P	CCLE	PASSENGER/OTHER	Probably Damaging
93	HT55	Cell Line	LARGE INTESTINE	NP_001057	c.1337_1338AG>TT	p.E446V	CCLE	PASSENGER/OTHER	Probably Damaging
94	KMBC2	Cell Line	URINARY TRACT	NP_001057	c.396G>A	p.E132E	CCLE	NP	NP
95	MDAMB231	Cell Line	BREAST	NP_001057	c.420G>C	p.L140L	CCLE	NP	NP
96	MEC1	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_001057	c.1264C>T	p.P422S	CCLE	PASSENGER/OTHER	Probably Damaging
97	MFE319	Cell Line	ENDOMETRIUM	NP_001057	c.458G>A	p.G153E	CCLE	PASSENGER/OTHER	Probably Damaging
98	MKN7	Cell Line	STOMACH	NP_001057	c.1034G>A	p.R345Q	CCLE	PASSENGER/OTHER	Benign
99	NCIH1793	Cell Line	LUNG	NP_001057	c.1070G>T	p.G357V	CCLE	PASSENGER/OTHER	Possibly Damaging
100	RERFLCAD1	Cell Line	LUNG	NP_001057	c.770A>C	p.D257A	CCLE	PASSENGER/OTHER	Benign
101	SNU81	Cell Line	LARGE INTESTINE	NP_001057	c.130G>T	p.E44*	CCLE	NP	NP
102	TEN	Cell Line	ENDOMETRIUM	NP_001057	c.396G>A	p.E132E	CCLE	NP	NP
103	YAPC	Cell Line	PANCREAS	NP_001057	c.925C>G	p.R309G	CCLE	PASSENGER/OTHER	Benign
104	22T	Tumour	SKIN	ENST00000376259	c.1275G>A	p.K425K	COSMIC	NP	NP
105	587238	Tumour	LARGE INTESTINE	ENST00000376259	c.251C>T	p.T84I	COSMIC	NP	NP
106	587278	Tumour	LARGE INTESTINE	ENST00000376259	c.769G>A	p.D257N	COSMIC	NP	NP
107	ESO-085	Tumour	OESOPHAGUS	ENST00000376259	c.1150_1164del15	p.I384_C388delIVNVC	COSMIC	NP	NP
108	ESO-164	Tumour	OESOPHAGUS	ENST00000376259	c.1291C>T	p.R431W	COSMIC	NP	NP
109	GC8	Tumour	T STOMACH	ENST00000376259	c.587T>G	p.M196R	COSMIC	NP	NP
110	HCC30T	Tumour	LIVER	ENST00000376259	c.916G>A	p.D306N	COSMIC	NP	NP
111	HCC4T	Tumour	LIVER	ENST00000376259	c.641T>C	p.V214A	COSMIC	NP	NP
112	HN	Tumour	62854 UPPER AERODIGESTIVE TRACT	ENST00000376259	c.1239G>T	p.S413S	COSMIC	NP	NP
113	HX13T	Tumour	LIVER	ENST00000376259	c.641T>C	p.V214A	COSMIC	NP	NP
114	LUAD-CHTN-MAD06-00668	Tumour	LUNG	ENST00000376259	c.303C>A	p.S101R	COSMIC	NP	NP
115	LUAD-F00365	Tumour	LUNG	ENST00000376259	c.134A>T	p.Y45F	COSMIC	NP	NP
116	TCGA-05-4398-01	Tumour	LUNG	ENST00000376259	c.425A>T	p.K142M	COSMIC	NP	NP
117	TCGA-06-0126-01	Tumour	CENTRAL NERVOUS SYSTEM	ENST00000376259	c.664A>C	p.T222P	COSMIC	NP	NP
118	TCGA-21-1078-01	Tumour	LUNG	ENST00000376259	c.436G>C	p.G146R	COSMIC	NP	NP
119	TCGA-64-5775-01	Tumour	LUNG	ENST00000376259	c.147A>T	p.T49T	COSMIC	NP	NP
120	TCGA-95-7947-01	Tumour	LUNG	ENST00000376259	c.609G>T	p.T203T	COSMIC	NP	NP
121	TCGA-A5-A0VP-01	Tumour	ENDOMETRIUM	ENST00000376259	c.609G>A	p.T203T	COSMIC	NP	NP
122	TCGA-AA-3655-01	Tumour	LARGE INTESTINE	ENST00000376259	c.666A>G	p.T222T	COSMIC	NP	NP
123	TCGA-AA-3662-01	Tumour	LARGE INTESTINE	ENST00000376259	c.665C>A	p.T222K	COSMIC	NP	NP
124	TCGA-AP-A051-01	Tumour	ENDOMETRIUM	ENST00000376259	c.475G>A	p.V159M	COSMIC	NP	NP
125	TCGA-CK-5916-01	Tumour	LARGE INTESTINE	ENST00000376259	c.1371G>A	p.G457G	COSMIC	NP	NP
126	TCGA-CM-6171-01	Tumour	LARGE INTESTINE	ENST00000376259	c.783A>C	p.P261P	COSMIC	NP	NP
127	TCGA-CU-A0YN-01	Tumour	URINARY TRACT	ENST00000376259	c.637G>C	p.A213P	COSMIC	NP	NP
128	TCGA-D1-A15X-01	Tumour	ENDOMETRIUM	ENST00000376259	c.109G>A	p.G37R	COSMIC	NP	NP
129	TCGA-FD-A3N5-01	Tumour	URINARY TRACT	ENST00000376259	c.422G>A	p.R141H	COSMIC	NP	NP
130	YUKLAB	Tumour	SKIN	ENST00000376259	c.1215G>A	p.M405I	COSMIC	NP	NP
131	YUKLAB	Tumour	SKIN	ENST00000376259	c.1225G>C	p.D409H	COSMIC	NP	NP
132	A431	Cell Line	SKIN	ENST00000376259	c.781C>T	p.P261S	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
133	A704	Cell Line	KIDNEY	ENST00000376259	c.345C>A	p.N115K	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
134	AN3CA	Cell Line	ENDOMETRIUM	ENST00000376259	c.673C>A	p.Q225K	COSMIC	PASSENGER/OTHER	BENIGN
135	BXPC3	Cell Line	PANCREAS	ENST00000376259	c.603G>A	p.T201T	COSMIC	NP	NP
136	C3A	Cell Line	LIVER	ENST00000376259	c.820C>T	p.L274L	COSMIC	NP	NP
137	CTV1	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000376259	c.735delG	p.G246fs*19	COSMIC	NP	NP
138	EBC1	Cell Line	LUNG	ENST00000376259	c.1292G>A	p.R431Q	COSMIC	PASSENGER/OTHER	BENIGN
139	EJM	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000376259	c.271C>T	p.P91S	COSMIC	PASSENGER/OTHER	BENIGN
140	GRST	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000376259	c.787+8G>A	p.?	COSMIC	NP	NP
141	HCC2218	Cell Line	BREAST	ENST00000376259	c.1109C>T	p.S370F	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
142	HCC33	Cell Line	LUNG	ENST00000376259	c.1106-8C>A	p.?	COSMIC	NP	NP
143	HCC33	Cell Line	LUNG	ENST00000376259	c.329G>T	p.C110F	COSMIC	CANCER	PROBABLY DAMAGING
144	HCC33	Cell Line	LUNG	ENST00000376259	c.331A>T	p.T111S	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
145	HEC1	Cell Line	ENDOMETRIUM	ENST00000376259	c.255G>T	p.Q85H	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
146	HT55	Cell Line	LARGE_INTESTINE	ENST00000376259	c.1337A>T	p.E446V	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
147	HT55	Cell Line	LARGE_INTESTINE	ENST00000376259	c.1338G>T	p.E446D	COSMIC	PASSENGER/OTHER	BENIGN
148	ISTSL2	Cell Line	LUNG	ENST00000376259	c.545A>C	p.H182P	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
149	KY821	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000376259	c.204C>G	p.T68T	COSMIC	NP	NP
150	KYSE30	Cell Line	OESOPHAGUS	ENST00000376259	c.178+8C>T	p.?	COSMIC	NP	NP
151	MCC13	Cell Line	SKIN	ENST00000376259	c.774C>T	p.F258F	COSMIC	NP	NP
152	MDAMB231	Cell Line	BREAST	ENST00000376259	c.420G>C	p.L140L	COSMIC	NP	NP
153	MFE319	Cell Line	ENDOMETRIUM	ENST00000376259	c.458G>A	p.G153E	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
154	SNU407	Cell Line	LARGE_INTESTINE	ENST00000376259	c.1239G>A	p.S413S	COSMIC	NP	NP
155	SNU81	Cell Line	LARGE_INTESTINE	ENST00000376259	c.130G>T	p.E44*	COSMIC	NP	NP
156	SUDHL6	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000376259	c.395A>T	p.E132V	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
157	SW872	Cell Line	SOFT_TISSUE	ENST00000376259	c.1292G>A	p.R431Q	COSMIC	PASSENGER/OTHER	BENIGN
158	TMK1	Cell Line	STOMACH	ENST00000376259	c.922G>A	p.A308T	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING

*NP: Not Predicted

Tissue Type	Mean Expression Value	Median Expression Value	Mean CNV	Median CNV

AUTONOMIC GANGLIA	4.0322	3.9556	-0.6933	-0.9477
BILIARY TRACT	5.1729	4.8566	-0.2668	-0.3217
BONE	4.5303	4.4397	0.0610	7e-04
BREAST	4.3571	4.1341	-0.2049	-0.1912
CENTRAL NERVOUS SYSTEM	4.4666	4.2895	-0.0810	-0.025
ENDOMETRIUM	4.0802	4.0964	0.0053	-0.0068
HAEMATOPOIETIC AND LYMPHOID TISSUE	6.2999	6.0933	0.0330	0.004691
KIDNEY	4.1450	4.0162	-0.3276	-0.1918
LARGE INTESTINE	6.1208	6.34465	-0.1349	-0.0505
LIVER	4.2714	4.0634	-0.0399	-0.0429
LUNG	4.4764	4.1805	-0.0964	-0.06775
OESOPHAGUS	4.7493	4.0097	-0.1143	-0.0396
OVARY	4.3314	4.095	-0.0095	0.0114
PANCREAS	5.5110	5.001	-0.1422	-0.1682
PLEURA	4.6989	4.7635	-0.2120	-0.1394
PROSTATE	4.0747	4.0377	0.0089	0.025807
SALIVARY GLAND	4.3892	4.3892	-0.4209	-0.4209
SKIN	4.5895	4.3544	0.0388	0.0179
SMALL INTESTINE	3.8973	3.8973	0.0328	0.03281
SOFT TISSUE	4.8537	4.35145	0.0613	0.0331
STOMACH	5.6705	4.86095	-0.0281	-0.07415
THYROID	4.5233	4.0636	0.1613	0.19305
UPPER AERODIGESTIVE TRACT	4.5898	4.32425	-0.1057	-0.01259
URINARY TRACT	4.5183	4.30885	-0.1158	-0.06027

Domain ID	Domain Name	Start Site	End Site	E-value
PF00020	TNFR_c6	40	75	2e-08
PF00020	TNFR_c6	78	118	1.1e-09
PF00020	TNFR_c6	120	161	0.018
PF06697	DUF1191	176	290	0.15
PF00020	TNFR_c6	40	75	2e-08
PF00020	TNFR_c6	78	118	1.1e-09
PF00020	TNFR_c6	120	161	0.018
PF06697	DUF1191	176	290	0.15

Proteomics DB	COSMIC	Gene Atlas	STRING	PIR
TNFRSF1B	TNFRSF1B	TNFRSF1B	ENSP00000365435	P20333
QuickGO	HGNC	Ensembl Genome Browser	TreeFam	UniProt
P20333	TNFRSF1B	ENSP00000365435	TNFRSF1B	P20333
Expression Atlas	Protein Atlas	OMIM	IntAct	PharmGKB
TNFRSF1B	ENSP00000365435	191191	P20333	PA36610

Protein: TNFRSF1B

Mutation Data (+)

Copy number variation and expression profile (+)

Gene Essentiality Data (+)

Tertiary structure (+)

Structure Domains (+)

Sequence Alignment (+)

Sequence Profiles (+)

Post Translational Modifications (+)

Other Databases Link (+)

Modelled Structure	Structures available in PDB
	1CA9, 3ALQ