ApoCanD

#	Name/ID	Cell Line/Tumor sample	Tissue of Origin	Reference ID	cDNA change	Protein change	Source	FATHMM Prediction	PolyPhen2 Prediction
1	A204	Cell Line	SOFT TISSUE	NP_003833	c.1164G>C	p.K388N	CCLE	PASSENGER/OTHER	Probably Damaging
2	A2780	Cell Line	OVARY	NP_003833	c.1252A>G	p.I418V	CCLE	PASSENGER/OTHER	Possibly Damaging
3	CMLT1	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_003833	c.343C>T	p.R115C	CCLE	PASSENGER/OTHER	Probably Damaging
4	EFE184	Cell Line	ENDOMETRIUM	NP_003833	c.349A>C	p.T117P	CCLE	PASSENGER/OTHER	Probably Damaging
5	HT1080	Cell Line	SOFT TISSUE	NP_003833	c.748_splice	p.G250_splice	CCLE	NP	NP
6	JHUEM7	Cell Line	ENDOMETRIUM	NP_003833	c.393G>A	p.T131T	CCLE	NP	NP
7	KASUMI2	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_003833	c.1277G>C	p.G426A	CCLE	PASSENGER/OTHER	Probably Damaging
8	MDAPCA2B	Cell Line	PROSTATE	NP_003833	c.598T>C	p.S200P	CCLE	PASSENGER/OTHER	Possibly Damaging
9	NCIH1092	Cell Line	LUNG	NP_003833	c.1178C>G	p.T393S	CCLE	PASSENGER/OTHER	Probably Damaging
10	NCIH209	Cell Line	LUNG	NP_003833	c.748_splice	p.G250_splice	CCLE	NP	NP
11	NCIH2110	Cell Line	LUNG	NP_003833	c.539A>T	p.H180L	CCLE	PASSENGER/OTHER	Possibly Damaging
12	NCIH510	Cell Line	LUNG	NP_003833	c.425G>T	p.G142V	CCLE	PASSENGER/OTHER	Probably Damaging
13	NUGC4	Cell Line	STOMACH	NP_003833	c.675_675delG	p.L225fs	CCLE	NP	NP
14	OCUM1	Cell Line	STOMACH	NP_003833	c.401A>G	p.N134S	CCLE	PASSENGER/OTHER	Possibly Damaging
15	OV56	Cell Line	OVARY	NP_003833	c.649G>A	p.G217R	CCLE	PASSENGER/OTHER	Probably Damaging
16	PECAPJ49	Cell Line	UPPER AERODIGESTIVE TRACT	NP_003833	c.598_598delT	p.S200fs	CCLE	NP	NP
17	PK59	Cell Line	PANCREAS	NP_003833	c.343C>T	p.R115C	CCLE	PASSENGER/OTHER	Probably Damaging
18	RT4	Cell Line	URINARY TRACT	NP_003833	c.748_splice	p.G250_splice	CCLE	NP	NP
19	SNU175	Cell Line	LARGE INTESTINE	NP_003833	c.231A>G	p.S77S	CCLE	NP	NP
20	SW1271	Cell Line	LUNG	NP_003833	c.700T>G	p.S234A	CCLE	PASSENGER/OTHER	Benign
21	CHC1061T	Tumour	LIVER	ENST00000276431	c.1181G>T	p.G394V	COSMIC	NP	NP
22	ESO-721	Tumour	OESOPHAGUS	ENST00000276431	c.23C>A	p.A8D	COSMIC	NP	NP
23	HCC105T	Tumour	LIVER	ENST00000276431	c.298G>T	p.G100*	COSMIC	NP	NP
24	HCC109T	Tumour	LIVER	ENST00000276431	c.766G>A	p.E256K	COSMIC	NP	NP
25	LUAD-B00416	Tumour	LUNG	ENST00000276431	c.1047G>T	p.V349V	COSMIC	NP	NP
26	LUAD-NYU627	Tumour	LUNG	ENST00000276431	c.921G>C	p.E307D	COSMIC	NP	NP
27	LUAD-YINHD	Tumour	LUNG	ENST00000276431	c.1269G>C	p.L423F	COSMIC	NP	NP
28	ME043T	Tumour	SKIN	ENST00000276431	c.226C>T	p.P76S	COSMIC	NP	NP
29	PD4200a	Tumour	NS	ENST00000276431	c.290G>A	p.C97Y	COSMIC	NP	NP
30	TCGA-18-3408-01	Tumour	LUNG	ENST00000276431	c.476+1G>T	p.?	COSMIC	NP	NP
31	TCGA-73-4677-01	Tumour	LUNG	ENST00000276431	c.1113T>C	p.A371A	COSMIC	NP	NP
32	TCGA-91-6848-01	Tumour	LUNG	ENST00000276431	c.22G>T	p.A8S	COSMIC	NP	NP
33	TCGA-A5-A0VP-01	Tumour	ENDOMETRIUM	ENST00000276431	c.470G>A	p.R157H	COSMIC	NP	NP
34	TCGA-AA-3710-01	Tumour	LARGE INTESTINE	ENST00000276431	c.1131C>A	p.G377G	COSMIC	NP	NP
35	TCGA-AA-3949-01	Tumour	LARGE INTESTINE	ENST00000276431	c.344G>A	p.R115H	COSMIC	NP	NP
36	TCGA-AA-3950-01	Tumour	LARGE INTESTINE	ENST00000276431	c.825C>G	p.I275M	COSMIC	NP	NP
37	TCGA-AA-A010-01	Tumour	LARGE INTESTINE	ENST00000276431	c.791G>A	p.R264Q	COSMIC	NP	NP
38	TCGA-AG-A002-01	Tumour	LARGE INTESTINE	ENST00000276431	c.418G>A	p.E140K	COSMIC	NP	NP
39	TCGA-AG-A002-01	Tumour	LARGE INTESTINE	ENST00000276431	c.529G>A	p.E177K	COSMIC	NP	NP
40	TCGA-AG-A002-01	Tumour	LARGE INTESTINE	ENST00000276431	c.820G>T	p.E274*	COSMIC	NP	NP
41	TCGA-AG-A036-01	Tumour	LARGE INTESTINE	ENST00000276431	c.463A>G	p.K155E	COSMIC	NP	NP
42	TCGA-AP-A0LM-01	Tumour	ENDOMETRIUM	ENST00000276431	c.649G>T	p.G217*	COSMIC	NP	NP
43	TCGA-AZ-4315-01	Tumour	LARGE INTESTINE	ENST00000276431	c.544G>T	p.E182*	COSMIC	NP	NP
44	TCGA-B5-A0JY-01	Tumour	ENDOMETRIUM	ENST00000276431	c.544G>T	p.E182*	COSMIC	NP	NP
45	TCGA-B5-A0JZ-01	Tumour	ENDOMETRIUM	ENST00000276431	c.1180G>A	p.G394R	COSMIC	NP	NP
46	TCGA-B5-A11E-01	Tumour	ENDOMETRIUM	ENST00000276431	c.528C>T	p.I176I	COSMIC	NP	NP
47	TCGA-B5-A11E-01	Tumour	ENDOMETRIUM	ENST00000276431	c.591G>A	p.T197T	COSMIC	NP	NP
48	TCGA-BG-A0LX-01	Tumour	ENDOMETRIUM	ENST00000276431	c.144+2T>C	p.?	COSMIC	NP	NP
49	YUCHIME	Tumour	SKIN	ENST00000276431	c.746C>T	p.S249L	COSMIC	NP	NP
50	YUPAT	Tumour	SKIN	ENST00000276431	c.982C>T	p.P328S	COSMIC	NP	NP
51	YUPROST	Tumour	SKIN	ENST00000276431	c.205C>T	p.P69S	COSMIC	NP	NP
52	ccRCC-98	Tumour	KIDNEY	ENST00000276431	c.985G>T	p.A329S	COSMIC	NP	NP
53	pfg016T	Tumour	STOMACH	ENST00000276431	c.923C>T	p.S308L	COSMIC	NP	NP
54	A204	Cell Line	SOFT_TISSUE	ENST00000276431	c.1164G>C	p.K388N	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
55	A2780	Cell Line	OVARY	ENST00000276431	c.1252A>G	p.I418V	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
56	CAL851	Cell Line	BREAST	ENST00000276431	c.592G>T	p.V198L	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
57	CMLT1	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000276431	c.343C>T	p.R115C	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
58	DEL	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000276431	c.1022G>C	p.C341S	COSMIC	PASSENGER/OTHER	BENIGN
59	DJM1	Cell Line	SKIN	ENST00000276431	c.544G>C	p.E182Q	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
60	ETK1	Cell Line	BILIARY_TRACT	ENST00000276431	c.662C>T	p.A221V	COSMIC	PASSENGER/OTHER	BENIGN
61	GOTO	Cell Line	AUTONOMIC_GANGLIA	ENST00000276431	c.662C>T	p.A221V	COSMIC	PASSENGER/OTHER	BENIGN
62	HEC1	Cell Line	ENDOMETRIUM	ENST00000276431	c.459C>A	p.C153*	COSMIC	NP	NP
63	JSC1	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000276431	c.1120G>A	p.E374K	COSMIC	PASSENGER/OTHER	BENIGN
64	KCL22	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000276431	c.691G>A	p.V231I	COSMIC	PASSENGER/OTHER	BENIGN
65	MC1010	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000276431	c.314C>T	p.T105I	COSMIC	PASSENGER/OTHER	BENIGN
66	MCC13	Cell Line	SKIN	ENST00000276431	c.435G>A	p.R145R	COSMIC	NP	NP
67	NCCIT	Cell Line	TESTIS	ENST00000276431	c.662C>T	p.A221V	COSMIC	PASSENGER/OTHER	BENIGN
68	NCIH1092	Cell Line	LUNG	ENST00000276431	c.1108G>T	p.V370L	COSMIC	PASSENGER/OTHER	BENIGN
69	NCIH1563	Cell Line	LUNG	ENST00000276431	c.732G>A	p.L244L	COSMIC	NP	NP
70	NCIH2110	Cell Line	LUNG	ENST00000276431	c.539A>T	p.H180L	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
71	NCIH3122	Cell Line	LUNG	ENST00000276431	c.667G>A	p.V223I	COSMIC	PASSENGER/OTHER	BENIGN
72	NCIH510A	Cell Line	LUNG	ENST00000276431	c.425G>T	p.G142V	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
73	NCIH510A	Cell Line	LUNG	ENST00000276431	c.86G>A	p.R29K	COSMIC	PASSENGER/OTHER	BENIGN
74	NUGC4	Cell Line	STOMACH	ENST00000276431	c.675delG	p.I226fs*19	COSMIC	NP	NP
75	OCUM1	Cell Line	STOMACH	ENST00000276431	c.401A>G	p.N134S	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
76	PF382	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000276431	c.1309T>A	p.S437T	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
77	RMGI	Cell Line	OVARY	ENST00000276431	c.662C>T	p.A221V	COSMIC	PASSENGER/OTHER	BENIGN
78	SCABER	Cell Line	URINARY_TRACT	ENST00000276431	c.188C>G	p.P63R	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
79	SKGIIIA	Cell Line	CERVIX	ENST00000276431	c.485G>C	p.R162T	COSMIC	PASSENGER/OTHER	BENIGN
80	SLVL	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000276431	c.597C>T	p.T199T	COSMIC	NP	NP
81	SNU1040	Cell Line	LARGE_INTESTINE	ENST00000276431	c.1004C>T	p.T335I	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
82	SNU1040	Cell Line	LARGE_INTESTINE	ENST00000276431	c.1287G>A	p.M429I	COSMIC	PASSENGER/OTHER	BENIGN
83	SNU175	Cell Line	LARGE_INTESTINE	ENST00000276431	c.231A>G	p.S77S	COSMIC	NP	NP
84	TC71	Cell Line	BONE	ENST00000276431	c.174A>T	p.Q58H	COSMIC	PASSENGER/OTHER	BENIGN
85	A204	Cell Line	SOFT TISSUE	NP_003833	c.1164G>C	p.K388N	CCLE	PASSENGER/OTHER	Probably Damaging
86	A2780	Cell Line	OVARY	NP_003833	c.1252A>G	p.I418V	CCLE	PASSENGER/OTHER	Possibly Damaging
87	CMLT1	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_003833	c.343C>T	p.R115C	CCLE	PASSENGER/OTHER	Probably Damaging
88	EFE184	Cell Line	ENDOMETRIUM	NP_003833	c.349A>C	p.T117P	CCLE	PASSENGER/OTHER	Probably Damaging
89	HT1080	Cell Line	SOFT TISSUE	NP_003833	c.748_splice	p.G250_splice	CCLE	NP	NP
90	JHUEM7	Cell Line	ENDOMETRIUM	NP_003833	c.393G>A	p.T131T	CCLE	NP	NP
91	KASUMI2	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_003833	c.1277G>C	p.G426A	CCLE	PASSENGER/OTHER	Probably Damaging
92	MDAPCA2B	Cell Line	PROSTATE	NP_003833	c.598T>C	p.S200P	CCLE	PASSENGER/OTHER	Possibly Damaging
93	NCIH1092	Cell Line	LUNG	NP_003833	c.1178C>G	p.T393S	CCLE	PASSENGER/OTHER	Probably Damaging
94	NCIH209	Cell Line	LUNG	NP_003833	c.748_splice	p.G250_splice	CCLE	NP	NP
95	NCIH2110	Cell Line	LUNG	NP_003833	c.539A>T	p.H180L	CCLE	PASSENGER/OTHER	Possibly Damaging
96	NCIH510	Cell Line	LUNG	NP_003833	c.425G>T	p.G142V	CCLE	PASSENGER/OTHER	Probably Damaging
97	NUGC4	Cell Line	STOMACH	NP_003833	c.675_675delG	p.L225fs	CCLE	NP	NP
98	OCUM1	Cell Line	STOMACH	NP_003833	c.401A>G	p.N134S	CCLE	PASSENGER/OTHER	Possibly Damaging
99	OV56	Cell Line	OVARY	NP_003833	c.649G>A	p.G217R	CCLE	PASSENGER/OTHER	Probably Damaging
100	PECAPJ49	Cell Line	UPPER AERODIGESTIVE TRACT	NP_003833	c.598_598delT	p.S200fs	CCLE	NP	NP
101	PK59	Cell Line	PANCREAS	NP_003833	c.343C>T	p.R115C	CCLE	PASSENGER/OTHER	Probably Damaging
102	RT4	Cell Line	URINARY TRACT	NP_003833	c.748_splice	p.G250_splice	CCLE	NP	NP
103	SNU175	Cell Line	LARGE INTESTINE	NP_003833	c.231A>G	p.S77S	CCLE	NP	NP
104	SW1271	Cell Line	LUNG	NP_003833	c.700T>G	p.S234A	CCLE	PASSENGER/OTHER	Benign
105	CHC1061T	Tumour	LIVER	ENST00000276431	c.1181G>T	p.G394V	COSMIC	NP	NP
106	ESO-721	Tumour	OESOPHAGUS	ENST00000276431	c.23C>A	p.A8D	COSMIC	NP	NP
107	HCC105T	Tumour	LIVER	ENST00000276431	c.298G>T	p.G100*	COSMIC	NP	NP
108	HCC109T	Tumour	LIVER	ENST00000276431	c.766G>A	p.E256K	COSMIC	NP	NP
109	LUAD-B00416	Tumour	LUNG	ENST00000276431	c.1047G>T	p.V349V	COSMIC	NP	NP
110	LUAD-NYU627	Tumour	LUNG	ENST00000276431	c.921G>C	p.E307D	COSMIC	NP	NP
111	LUAD-YINHD	Tumour	LUNG	ENST00000276431	c.1269G>C	p.L423F	COSMIC	NP	NP
112	ME043T	Tumour	SKIN	ENST00000276431	c.226C>T	p.P76S	COSMIC	NP	NP
113	PD4200a	Tumour	NS	ENST00000276431	c.290G>A	p.C97Y	COSMIC	NP	NP
114	TCGA-18-3408-01	Tumour	LUNG	ENST00000276431	c.476+1G>T	p.?	COSMIC	NP	NP
115	TCGA-73-4677-01	Tumour	LUNG	ENST00000276431	c.1113T>C	p.A371A	COSMIC	NP	NP
116	TCGA-91-6848-01	Tumour	LUNG	ENST00000276431	c.22G>T	p.A8S	COSMIC	NP	NP
117	TCGA-A5-A0VP-01	Tumour	ENDOMETRIUM	ENST00000276431	c.470G>A	p.R157H	COSMIC	NP	NP
118	TCGA-AA-3710-01	Tumour	LARGE INTESTINE	ENST00000276431	c.1131C>A	p.G377G	COSMIC	NP	NP
119	TCGA-AA-3949-01	Tumour	LARGE INTESTINE	ENST00000276431	c.344G>A	p.R115H	COSMIC	NP	NP
120	TCGA-AA-3950-01	Tumour	LARGE INTESTINE	ENST00000276431	c.825C>G	p.I275M	COSMIC	NP	NP
121	TCGA-AA-A010-01	Tumour	LARGE INTESTINE	ENST00000276431	c.791G>A	p.R264Q	COSMIC	NP	NP
122	TCGA-AG-A002-01	Tumour	LARGE INTESTINE	ENST00000276431	c.418G>A	p.E140K	COSMIC	NP	NP
123	TCGA-AG-A002-01	Tumour	LARGE INTESTINE	ENST00000276431	c.529G>A	p.E177K	COSMIC	NP	NP
124	TCGA-AG-A002-01	Tumour	LARGE INTESTINE	ENST00000276431	c.820G>T	p.E274*	COSMIC	NP	NP
125	TCGA-AG-A036-01	Tumour	LARGE INTESTINE	ENST00000276431	c.463A>G	p.K155E	COSMIC	NP	NP
126	TCGA-AP-A0LM-01	Tumour	ENDOMETRIUM	ENST00000276431	c.649G>T	p.G217*	COSMIC	NP	NP
127	TCGA-AZ-4315-01	Tumour	LARGE INTESTINE	ENST00000276431	c.544G>T	p.E182*	COSMIC	NP	NP
128	TCGA-B5-A0JY-01	Tumour	ENDOMETRIUM	ENST00000276431	c.544G>T	p.E182*	COSMIC	NP	NP
129	TCGA-B5-A0JZ-01	Tumour	ENDOMETRIUM	ENST00000276431	c.1180G>A	p.G394R	COSMIC	NP	NP
130	TCGA-B5-A11E-01	Tumour	ENDOMETRIUM	ENST00000276431	c.528C>T	p.I176I	COSMIC	NP	NP
131	TCGA-B5-A11E-01	Tumour	ENDOMETRIUM	ENST00000276431	c.591G>A	p.T197T	COSMIC	NP	NP
132	TCGA-BG-A0LX-01	Tumour	ENDOMETRIUM	ENST00000276431	c.144+2T>C	p.?	COSMIC	NP	NP
133	YUCHIME	Tumour	SKIN	ENST00000276431	c.746C>T	p.S249L	COSMIC	NP	NP
134	YUPAT	Tumour	SKIN	ENST00000276431	c.982C>T	p.P328S	COSMIC	NP	NP
135	YUPROST	Tumour	SKIN	ENST00000276431	c.205C>T	p.P69S	COSMIC	NP	NP
136	ccRCC-98	Tumour	KIDNEY	ENST00000276431	c.985G>T	p.A329S	COSMIC	NP	NP
137	pfg016T	Tumour	STOMACH	ENST00000276431	c.923C>T	p.S308L	COSMIC	NP	NP
138	A204	Cell Line	SOFT_TISSUE	ENST00000276431	c.1164G>C	p.K388N	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
139	A2780	Cell Line	OVARY	ENST00000276431	c.1252A>G	p.I418V	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
140	CAL851	Cell Line	BREAST	ENST00000276431	c.592G>T	p.V198L	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
141	CMLT1	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000276431	c.343C>T	p.R115C	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
142	DEL	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000276431	c.1022G>C	p.C341S	COSMIC	PASSENGER/OTHER	BENIGN
143	DJM1	Cell Line	SKIN	ENST00000276431	c.544G>C	p.E182Q	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
144	ETK1	Cell Line	BILIARY_TRACT	ENST00000276431	c.662C>T	p.A221V	COSMIC	PASSENGER/OTHER	BENIGN
145	GOTO	Cell Line	AUTONOMIC_GANGLIA	ENST00000276431	c.662C>T	p.A221V	COSMIC	PASSENGER/OTHER	BENIGN
146	HEC1	Cell Line	ENDOMETRIUM	ENST00000276431	c.459C>A	p.C153*	COSMIC	NP	NP
147	JSC1	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000276431	c.1120G>A	p.E374K	COSMIC	PASSENGER/OTHER	BENIGN
148	KCL22	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000276431	c.691G>A	p.V231I	COSMIC	PASSENGER/OTHER	BENIGN
149	MC1010	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000276431	c.314C>T	p.T105I	COSMIC	PASSENGER/OTHER	BENIGN
150	MCC13	Cell Line	SKIN	ENST00000276431	c.435G>A	p.R145R	COSMIC	NP	NP
151	NCCIT	Cell Line	TESTIS	ENST00000276431	c.662C>T	p.A221V	COSMIC	PASSENGER/OTHER	BENIGN
152	NCIH1092	Cell Line	LUNG	ENST00000276431	c.1108G>T	p.V370L	COSMIC	PASSENGER/OTHER	BENIGN
153	NCIH1563	Cell Line	LUNG	ENST00000276431	c.732G>A	p.L244L	COSMIC	NP	NP
154	NCIH2110	Cell Line	LUNG	ENST00000276431	c.539A>T	p.H180L	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
155	NCIH3122	Cell Line	LUNG	ENST00000276431	c.667G>A	p.V223I	COSMIC	PASSENGER/OTHER	BENIGN
156	NCIH510A	Cell Line	LUNG	ENST00000276431	c.425G>T	p.G142V	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
157	NCIH510A	Cell Line	LUNG	ENST00000276431	c.86G>A	p.R29K	COSMIC	PASSENGER/OTHER	BENIGN
158	NUGC4	Cell Line	STOMACH	ENST00000276431	c.675delG	p.I226fs*19	COSMIC	NP	NP
159	OCUM1	Cell Line	STOMACH	ENST00000276431	c.401A>G	p.N134S	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
160	PF382	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000276431	c.1309T>A	p.S437T	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
161	RMGI	Cell Line	OVARY	ENST00000276431	c.662C>T	p.A221V	COSMIC	PASSENGER/OTHER	BENIGN
162	SCABER	Cell Line	URINARY_TRACT	ENST00000276431	c.188C>G	p.P63R	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
163	SKGIIIA	Cell Line	CERVIX	ENST00000276431	c.485G>C	p.R162T	COSMIC	PASSENGER/OTHER	BENIGN
164	SLVL	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000276431	c.597C>T	p.T199T	COSMIC	NP	NP
165	SNU1040	Cell Line	LARGE_INTESTINE	ENST00000276431	c.1004C>T	p.T335I	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
166	SNU1040	Cell Line	LARGE_INTESTINE	ENST00000276431	c.1287G>A	p.M429I	COSMIC	PASSENGER/OTHER	BENIGN
167	SNU175	Cell Line	LARGE_INTESTINE	ENST00000276431	c.231A>G	p.S77S	COSMIC	NP	NP
168	TC71	Cell Line	BONE	ENST00000276431	c.174A>T	p.Q58H	COSMIC	PASSENGER/OTHER	BENIGN

*NP: Not Predicted

Tissue Type	Mean Expression Value	Median Expression Value	Mean CNV	Median CNV

AUTONOMIC GANGLIA	7.2940	7.4542	0.0821	0.07934
BILIARY TRACT	7.3439	7.6504	-0.3660	-0.3367
BONE	7.8065	7.6062	0.0938	0.0328
BREAST	6.6778	6.69565	-0.6514	-0.5984
CENTRAL NERVOUS SYSTEM	7.8804	7.8691	-0.0482	0.0273
ENDOMETRIUM	8.2583	8.3394	0.0026	0.0214
HAEMATOPOIETIC AND LYMPHOID TISSUE	6.8192	6.9566	0.0556	0.0511
KIDNEY	8.3824	8.3024	-0.2463	-0.0994
LARGE INTESTINE	7.6886	7.7778	-0.3056	-0.056065
LIVER	7.3900	7.121	-0.3497	-0.331
LUNG	6.7445	7.17085	-0.3247	-0.34085
OESOPHAGUS	7.6009	7.78955	-0.1775	-0.10215
OVARY	7.4886	7.3975	-0.2618	-0.2519
PANCREAS	7.6803	7.7135	-0.5878	-0.5382
PLEURA	7.9895	7.8459	-0.2241	-0.1332
PROSTATE	7.5911	7.94785	-0.1334	-0.1648
SALIVARY GLAND	6.7766	6.7766	0.4381	0.4381
SKIN	8.0650	8.1032	-0.0515	0.037
SMALL INTESTINE	7.6102	7.6102	0.0403	0.0403
SOFT TISSUE	8.0106	7.825	-0.0076	0.0203
STOMACH	7.6342	7.8088	-0.1793	-0.12495
THYROID	7.8766	7.7725	-0.2775	-0.28845
UPPER AERODIGESTIVE TRACT	7.5603	7.45535	-0.4724	-0.4713
URINARY TRACT	7.6833	7.6304	-0.3087	-0.3238

Domain ID	Domain Name	Start Site	End Site	E-value
PF12662	cEGF	81	95	0.61
PF00020	TNFR_c6	97	137	7.3e-10
PF00020	TNFR_c6	139	178	0.00057
PF00531	Death	341	421	2.2e-16
PF12662	cEGF	81	95	0.61
PF00020	TNFR_c6	97	137	7.3e-10
PF00020	TNFR_c6	139	178	0.00057
PF00531	Death	341	421	2.2e-16

Proteomics DB	COSMIC	Gene Atlas	STRING	PIR
TNFRSF10B	TNFRSF10B	TNFRSF10B	ENSP00000276431	O14763
QuickGO	HGNC	Ensembl Genome Browser	TreeFam	UniProt
O14763	TNFRSF10B	ENSP00000276431	TNFRSF10B	O14763
Expression Atlas	Protein Atlas	OMIM	IntAct	PharmGKB
TNFRSF10B	ENSP00000276431	603612	O14763	PA36598

Protein: TNFRSF10B

Mutation Data (+)

Copy number variation and expression profile (+)

Gene Essentiality Data (+)

Tertiary structure (+)

Structure Domains (+)

Sequence Alignment (+)

Sequence Profiles (+)

Post Translational Modifications (+)

Other Databases Link (+)

Modelled Structure	Structures available in PDB
	1D0G, 1D4V, 1DU3, 1ZA3, 2H9G, 4I9X