ApoCanD

#	Name/ID	Cell Line/Tumor sample	Tissue of Origin	Reference ID	cDNA change	Protein change	Source	FATHMM Prediction	PolyPhen2 Prediction
1	AU565	Cell Line	BREAST	NP_006862	c.81C>T	p.V27V	CCLE	NP	NP
2	COV644	Cell Line	OVARY	NP_006862	c.713A>G	p.N238S	CCLE	PASSENGER/OTHER	Benign
3	HCT116	Cell Line	LARGE INTESTINE	NP_006862	c.308C>T	p.S103L	CCLE	PASSENGER/OTHER	Benign
4	HEC251	Cell Line	ENDOMETRIUM	NP_006862	c.288C>A	p.F96L	CCLE	CANCER	Probably Damaging
5	HEC59	Cell Line	ENDOMETRIUM	NP_006862	c.518G>A	p.G173E	CCLE	PASSENGER/OTHER	Possibly Damaging
6	KYSE150	Cell Line	OESOPHAGUS	NP_006862	c.142G>A	p.A48T	CCLE	CANCER	Probably Damaging
7	KYSE180	Cell Line	OESOPHAGUS	NP_006862	c.1099A>T	p.S367C	CCLE	CANCER	Probably Damaging
8	LOVO	Cell Line	LARGE INTESTINE	NP_006862	c.1475_1475delC	p.P492fs	CCLE	NP	NP
9	LOVO	Cell Line	LARGE INTESTINE	NP_006862	c.466G>A	p.V156I	CCLE	CANCER	Benign
10	MELHO	Cell Line	SKIN	NP_006862	c.1284G>C	p.E428D	CCLE	PASSENGER/OTHER	Benign
11	NCCSTCK140	Cell Line	STOMACH	NP_006862	c.725_725delT	p.L242fs	CCLE	NP	NP
12	NCIH1755	Cell Line	LUNG	NP_006862	c.1549G>A	p.G517R	CCLE	CANCER	Benign
13	NCIH929	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_006862	c.1518G>A	p.W506*	CCLE	NP	NP
14	OC316	Cell Line	OVARY	NP_006862	c.163A>T	p.K55*	CCLE	NP	NP
15	RCHACV	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_006862	c.1429T>C	p.W477R	CCLE	PASSENGER/OTHER	Benign
16	RCHACV	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_006862	c.345G>A	p.P115P	CCLE	NP	NP
17	SBC5	Cell Line	LUNG	NP_006862	c.466G>T	p.V156F	CCLE	CANCER	Possibly Damaging
18	SKBR3	Cell Line	BREAST	NP_006862	c.81C>T	p.V27V	CCLE	NP	NP
19	SNU1040	Cell Line	LARGE INTESTINE	NP_006862	c.124A>G	p.K42E	CCLE	PASSENGER/OTHER	Possibly Damaging
20	SNUC5	Cell Line	LARGE INTESTINE	NP_006862	c.652A>G	p.R218G	CCLE	PASSENGER/OTHER	Probably Damaging
21	SUPHD1	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_006862	c.1475_1476insC	p.P492fs	CCLE	NP	NP
22	TEN	Cell Line	ENDOMETRIUM	NP_006862	c.303C>T	p.S101S	CCLE	NP	NP
23	TGBC11TKB	Cell Line	STOMACH	NP_006862	c.760G>A	p.G254S	CCLE	CANCER	Probably Damaging
24	16660	Tumour	LUNG	ENST00000216274	c.38C>T	p.A13V	COSMIC	NP	NP
25	587278	Tumour	LARGE INTESTINE	ENST00000216274	c.565G>T	p.E189*	COSMIC	NP	NP
26	587376	Tumour	LARGE INTESTINE	ENST00000216274	c.1255C>T	p.P419S	COSMIC	NP	NP
27	ESO-1488	Tumour	OESOPHAGUS	ENST00000216274	c.298G>A	p.G100S	COSMIC	NP	NP
28	HCC98T	Tumour	LIVER	ENST00000216274	c.323C>A	p.S108Y	COSMIC	NP	NP
29	HN	Tumour	62854 UPPER AERODIGESTIVE TRACT	ENST00000216274	c.1173G>A	p.S391S	COSMIC	NP	NP
30	ME018T	Tumour	NS	ENST00000216274	c.1492G>A	p.E498K	COSMIC	NP	NP
31	NB-0121	Tumour	AUTONOMIC GANGLIA	ENST00000216274	c.581T>A	p.V194E	COSMIC	NP	NP
32	PD1487a	Tumour	CENTRAL NERVOUS SYSTEM	ENST00000216274	c.111G>A	p.R37R	COSMIC	NP	NP
33	PR-0099	Tumour	PROSTATE	ENST00000216274	c.271G>T	p.A91S	COSMIC	NP	NP
34	TCGA-02-0043-01	Tumour	CENTRAL NERVOUS SYSTEM	ENST00000216274	c.1515C>T	p.A505A	COSMIC	NP	NP
35	TCGA-04-1338-01	Tumour	OVARY	ENST00000216274	c.633G>A	p.M211I	COSMIC	NP	NP
36	TCGA-05-5420-01	Tumour	LUNG	ENST00000216274	c.398A>T	p.D133V	COSMIC	NP	NP
37	TCGA-10-0938-01	Tumour	OVARY	ENST00000216274	c.901-2A>T	p.?	COSMIC	NP	NP
38	TCGA-39-5036-01	Tumour	LUNG	ENST00000216274	c.1445C>T	p.S482L	COSMIC	NP	NP
39	TCGA-A8-A07R-01	Tumour	BREAST	ENST00000216274	c.30T>A	p.G10G	COSMIC	NP	NP
40	TCGA-A8-A08L-01	Tumour	BREAST	ENST00000216274	c.70C>T	p.Q24*	COSMIC	NP	NP
41	TCGA-AA-3542-01	Tumour	LARGE INTESTINE	ENST00000216274	c.215T>C	p.V72A	COSMIC	NP	NP
42	TCGA-AA-3833-01	Tumour	LARGE INTESTINE	ENST00000216274	c.421C>G	p.R141G	COSMIC	NP	NP
43	TCGA-AA-3864-01	Tumour	LARGE INTESTINE	ENST00000216274	c.1317G>A	p.P439P	COSMIC	NP	NP
44	TCGA-AA-3977-01	Tumour	LARGE INTESTINE	ENST00000216274	c.297C>T	p.N99N	COSMIC	NP	NP
45	TCGA-AA-3980-01	Tumour	LARGE INTESTINE	ENST00000216274	c.1372delG	p.V458fs*9	COSMIC	NP	NP
46	TCGA-AA-A00N-01	Tumour	LARGE INTESTINE	ENST00000216274	c.1172C>T	p.S391L	COSMIC	NP	NP
47	TCGA-AG-A002-01	Tumour	LARGE INTESTINE	ENST00000216274	c.621C>T	p.F207F	COSMIC	NP	NP
48	TCGA-AP-A051-01	Tumour	ENDOMETRIUM	ENST00000216274	c.1230C>T	p.S410S	COSMIC	NP	NP
49	TCGA-AP-A056-01	Tumour	ENDOMETRIUM	ENST00000216274	c.184A>G	p.K62E	COSMIC	NP	NP
50	TCGA-AP-A0LM-01	Tumour	ENDOMETRIUM	ENST00000216274	c.1339C>T	p.R447*	COSMIC	NP	NP
51	TCGA-AP-A0LM-01	Tumour	ENDOMETRIUM	ENST00000216274	c.167C>T	p.A56V	COSMIC	NP	NP
52	TCGA-AX-A0J1-01	Tumour	ENDOMETRIUM	ENST00000216274	c.1339C>T	p.R447*	COSMIC	NP	NP
53	TCGA-BP-4985-01	Tumour	KIDNEY	ENST00000216274	c.240G>A	p.E80E	COSMIC	NP	NP
54	TCGA-C8-A278-01	Tumour	BREAST	ENST00000216274	c.136G>A	p.D46N	COSMIC	NP	NP
55	TCGA-CJ-4882-01	Tumour	KIDNEY	ENST00000216274	c.244G>A	p.V82M	COSMIC	NP	NP
56	TCGA-D1-A0ZO-01	Tumour	ENDOMETRIUM	ENST00000216274	c.324C>T	p.S108S	COSMIC	NP	NP
57	TCGA-D1-A17Q-01	Tumour	ENDOMETRIUM	ENST00000216274	c.1348G>A	p.V450I	COSMIC	NP	NP
58	TCGA-D1-A17U-01	Tumour	ENDOMETRIUM	ENST00000216274	c.733C>T	p.L245L	COSMIC	NP	NP
59	TCGA-DY-A1H8-01	Tumour	LARGE INTESTINE	ENST00000216274	c.1132C>T	p.Q378*	COSMIC	NP	NP
60	TCGA-G4-6588-01	Tumour	LARGE INTESTINE	ENST00000216274	c.309G>A	p.S103S	COSMIC	NP	NP
61	TCGA-G4-6626-01	Tumour	LARGE INTESTINE	ENST00000216274	c.110G>T	p.R37L	COSMIC	NP	NP
62	TCGA-G9-6356-01	Tumour	PROSTATE	ENST00000216274	c.304T>C	p.L102L	COSMIC	NP	NP
63	cSCCP6	Tumour	SKIN	ENST00000216274	c.967G>A	p.G323R	COSMIC	NP	NP
64	tumor	Tumour	4163639 HAEMATOPOIETIC AND LYMPHOID TISSUE	ENST00000216274	c.448C>T	p.L150L	COSMIC	NP	NP
65	AN3CA	Cell Line	ENDOMETRIUM	ENST00000216274	c.1315C>T	p.P439S	COSMIC	PASSENGER/OTHER	BENIGN
66	BFTC909	Cell Line	KIDNEY	ENST00000216274	c.1173G>A	p.S391S	COSMIC	NP	NP
67	DG75	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000216274	c.1469_1470insC	p.P493fs*9	COSMIC	NP	NP
68	HCT116	Cell Line	LARGE_INTESTINE	ENST00000216274	c.308C>T	p.S103L	COSMIC	PASSENGER/OTHER	BENIGN
69	JHU022	Cell Line	UPPER_AERODIGESTIVE_TRACT	ENST00000216274	c.621C>T	p.F207F	COSMIC	NP	NP
70	JHU022	Cell Line	UPPER_AERODIGESTIVE_TRACT	ENST00000216274	c.832G>T	p.E278*	COSMIC	NP	NP
71	KYSE150	Cell Line	OESOPHAGUS	ENST00000216274	c.142G>A	p.A48T	COSMIC	CANCER	PROBABLY DAMAGING
72	KYSE180	Cell Line	OESOPHAGUS	ENST00000216274	c.1099A>T	p.S367C	COSMIC	CANCER	PROBABLY DAMAGING
73	LOVO	Cell Line	LARGE_INTESTINE	ENST00000216274	c.1475delC	p.P492fs*3	COSMIC	NP	NP
74	LOVO	Cell Line	LARGE_INTESTINE	ENST00000216274	c.466G>A	p.V156I	COSMIC	CANCER	BENIGN
75	LS180	Cell Line	LARGE_INTESTINE	ENST00000216274	c.1301G>C	p.W434S	COSMIC	PASSENGER/OTHER	BENIGN
76	MELHO	Cell Line	SKIN	ENST00000216274	c.1284G>C	p.E428D	COSMIC	PASSENGER/OTHER	BENIGN
77	MFE319	Cell Line	ENDOMETRIUM	ENST00000216274	c.1497C>T	p.G499G	COSMIC	NP	NP
78	MOLT4	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000216274	c.1339C>T	p.R447*	COSMIC	NP	NP
79	NCCIT	Cell Line	TESTIS	ENST00000216274	c.1074C>T	p.P358P	COSMIC	NP	NP
80	NCIH1755	Cell Line	LUNG	ENST00000216274	c.1549G>A	p.G517R	COSMIC	CANCER	BENIGN
81	NCIH2085	Cell Line	LUNG	ENST00000216274	c.958T>C	p.S320P	COSMIC	CANCER	BENIGN
82	NCIH929	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000216274	c.1518G>A	p.W506*	COSMIC	NP	NP
83	OC314	Cell Line	OVARY	ENST00000216274	c.163A>T	p.K55*	COSMIC	NP	NP
84	RCHACV	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000216274	c.1429T>C	p.W477R	COSMIC	PASSENGER/OTHER	BENIGN
85	RCHACV	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000216274	c.345G>A	p.P115P	COSMIC	NP	NP
86	RCK8	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000216274	c.1261C>T	p.P421S	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
87	RCK8	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000216274	c.396C>T	p.H132H	COSMIC	NP	NP
88	RPMI8402	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000216274	c.1054C>T	p.L352L	COSMIC	NP	NP
89	SKMG1	Cell Line	CENTRAL_NERVOUS_SYSTEM	ENST00000216274	c.1411A>G	p.T471A	COSMIC	PASSENGER/OTHER	BENIGN
90	SNUC1	Cell Line	LARGE_INTESTINE	ENST00000216274	c.1348G>A	p.V450I	COSMIC	PASSENGER/OTHER	BENIGN
91	TGBC11TKB	Cell Line	STOMACH	ENST00000216274	c.760G>A	p.G254S	COSMIC	CANCER	PROBABLY DAMAGING
92	VMRCMELG	Cell Line	SKIN	ENST00000216274	c.1054C>T	p.L352L	COSMIC	NP	NP
93	AU565	Cell Line	BREAST	NP_006862	c.81C>T	p.V27V	CCLE	NP	NP
94	COV644	Cell Line	OVARY	NP_006862	c.713A>G	p.N238S	CCLE	PASSENGER/OTHER	Benign
95	HCT116	Cell Line	LARGE INTESTINE	NP_006862	c.308C>T	p.S103L	CCLE	PASSENGER/OTHER	Benign
96	HEC251	Cell Line	ENDOMETRIUM	NP_006862	c.288C>A	p.F96L	CCLE	CANCER	Probably Damaging
97	HEC59	Cell Line	ENDOMETRIUM	NP_006862	c.518G>A	p.G173E	CCLE	PASSENGER/OTHER	Possibly Damaging
98	KYSE150	Cell Line	OESOPHAGUS	NP_006862	c.142G>A	p.A48T	CCLE	CANCER	Probably Damaging
99	KYSE180	Cell Line	OESOPHAGUS	NP_006862	c.1099A>T	p.S367C	CCLE	CANCER	Probably Damaging
100	LOVO	Cell Line	LARGE INTESTINE	NP_006862	c.1475_1475delC	p.P492fs	CCLE	NP	NP
101	LOVO	Cell Line	LARGE INTESTINE	NP_006862	c.466G>A	p.V156I	CCLE	CANCER	Benign
102	MELHO	Cell Line	SKIN	NP_006862	c.1284G>C	p.E428D	CCLE	PASSENGER/OTHER	Benign
103	NCCSTCK140	Cell Line	STOMACH	NP_006862	c.725_725delT	p.L242fs	CCLE	NP	NP
104	NCIH1755	Cell Line	LUNG	NP_006862	c.1549G>A	p.G517R	CCLE	CANCER	Benign
105	NCIH929	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_006862	c.1518G>A	p.W506*	CCLE	NP	NP
106	OC316	Cell Line	OVARY	NP_006862	c.163A>T	p.K55*	CCLE	NP	NP
107	RCHACV	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_006862	c.1429T>C	p.W477R	CCLE	PASSENGER/OTHER	Benign
108	RCHACV	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_006862	c.345G>A	p.P115P	CCLE	NP	NP
109	SBC5	Cell Line	LUNG	NP_006862	c.466G>T	p.V156F	CCLE	CANCER	Possibly Damaging
110	SKBR3	Cell Line	BREAST	NP_006862	c.81C>T	p.V27V	CCLE	NP	NP
111	SNU1040	Cell Line	LARGE INTESTINE	NP_006862	c.124A>G	p.K42E	CCLE	PASSENGER/OTHER	Possibly Damaging
112	SNUC5	Cell Line	LARGE INTESTINE	NP_006862	c.652A>G	p.R218G	CCLE	PASSENGER/OTHER	Probably Damaging
113	SUPHD1	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_006862	c.1475_1476insC	p.P492fs	CCLE	NP	NP
114	TEN	Cell Line	ENDOMETRIUM	NP_006862	c.303C>T	p.S101S	CCLE	NP	NP
115	TGBC11TKB	Cell Line	STOMACH	NP_006862	c.760G>A	p.G254S	CCLE	CANCER	Probably Damaging
116	16660	Tumour	LUNG	ENST00000216274	c.38C>T	p.A13V	COSMIC	NP	NP
117	587278	Tumour	LARGE INTESTINE	ENST00000216274	c.565G>T	p.E189*	COSMIC	NP	NP
118	587376	Tumour	LARGE INTESTINE	ENST00000216274	c.1255C>T	p.P419S	COSMIC	NP	NP
119	ESO-1488	Tumour	OESOPHAGUS	ENST00000216274	c.298G>A	p.G100S	COSMIC	NP	NP
120	HCC98T	Tumour	LIVER	ENST00000216274	c.323C>A	p.S108Y	COSMIC	NP	NP
121	HN	Tumour	62854 UPPER AERODIGESTIVE TRACT	ENST00000216274	c.1173G>A	p.S391S	COSMIC	NP	NP
122	ME018T	Tumour	NS	ENST00000216274	c.1492G>A	p.E498K	COSMIC	NP	NP
123	NB-0121	Tumour	AUTONOMIC GANGLIA	ENST00000216274	c.581T>A	p.V194E	COSMIC	NP	NP
124	PD1487a	Tumour	CENTRAL NERVOUS SYSTEM	ENST00000216274	c.111G>A	p.R37R	COSMIC	NP	NP
125	PR-0099	Tumour	PROSTATE	ENST00000216274	c.271G>T	p.A91S	COSMIC	NP	NP
126	TCGA-02-0043-01	Tumour	CENTRAL NERVOUS SYSTEM	ENST00000216274	c.1515C>T	p.A505A	COSMIC	NP	NP
127	TCGA-04-1338-01	Tumour	OVARY	ENST00000216274	c.633G>A	p.M211I	COSMIC	NP	NP
128	TCGA-05-5420-01	Tumour	LUNG	ENST00000216274	c.398A>T	p.D133V	COSMIC	NP	NP
129	TCGA-10-0938-01	Tumour	OVARY	ENST00000216274	c.901-2A>T	p.?	COSMIC	NP	NP
130	TCGA-39-5036-01	Tumour	LUNG	ENST00000216274	c.1445C>T	p.S482L	COSMIC	NP	NP
131	TCGA-A8-A07R-01	Tumour	BREAST	ENST00000216274	c.30T>A	p.G10G	COSMIC	NP	NP
132	TCGA-A8-A08L-01	Tumour	BREAST	ENST00000216274	c.70C>T	p.Q24*	COSMIC	NP	NP
133	TCGA-AA-3542-01	Tumour	LARGE INTESTINE	ENST00000216274	c.215T>C	p.V72A	COSMIC	NP	NP
134	TCGA-AA-3833-01	Tumour	LARGE INTESTINE	ENST00000216274	c.421C>G	p.R141G	COSMIC	NP	NP
135	TCGA-AA-3864-01	Tumour	LARGE INTESTINE	ENST00000216274	c.1317G>A	p.P439P	COSMIC	NP	NP
136	TCGA-AA-3977-01	Tumour	LARGE INTESTINE	ENST00000216274	c.297C>T	p.N99N	COSMIC	NP	NP
137	TCGA-AA-3980-01	Tumour	LARGE INTESTINE	ENST00000216274	c.1372delG	p.V458fs*9	COSMIC	NP	NP
138	TCGA-AA-A00N-01	Tumour	LARGE INTESTINE	ENST00000216274	c.1172C>T	p.S391L	COSMIC	NP	NP
139	TCGA-AG-A002-01	Tumour	LARGE INTESTINE	ENST00000216274	c.621C>T	p.F207F	COSMIC	NP	NP
140	TCGA-AP-A051-01	Tumour	ENDOMETRIUM	ENST00000216274	c.1230C>T	p.S410S	COSMIC	NP	NP
141	TCGA-AP-A056-01	Tumour	ENDOMETRIUM	ENST00000216274	c.184A>G	p.K62E	COSMIC	NP	NP
142	TCGA-AP-A0LM-01	Tumour	ENDOMETRIUM	ENST00000216274	c.1339C>T	p.R447*	COSMIC	NP	NP
143	TCGA-AP-A0LM-01	Tumour	ENDOMETRIUM	ENST00000216274	c.167C>T	p.A56V	COSMIC	NP	NP
144	TCGA-AX-A0J1-01	Tumour	ENDOMETRIUM	ENST00000216274	c.1339C>T	p.R447*	COSMIC	NP	NP
145	TCGA-BP-4985-01	Tumour	KIDNEY	ENST00000216274	c.240G>A	p.E80E	COSMIC	NP	NP
146	TCGA-C8-A278-01	Tumour	BREAST	ENST00000216274	c.136G>A	p.D46N	COSMIC	NP	NP
147	TCGA-CJ-4882-01	Tumour	KIDNEY	ENST00000216274	c.244G>A	p.V82M	COSMIC	NP	NP
148	TCGA-D1-A0ZO-01	Tumour	ENDOMETRIUM	ENST00000216274	c.324C>T	p.S108S	COSMIC	NP	NP
149	TCGA-D1-A17Q-01	Tumour	ENDOMETRIUM	ENST00000216274	c.1348G>A	p.V450I	COSMIC	NP	NP
150	TCGA-D1-A17U-01	Tumour	ENDOMETRIUM	ENST00000216274	c.733C>T	p.L245L	COSMIC	NP	NP
151	TCGA-DY-A1H8-01	Tumour	LARGE INTESTINE	ENST00000216274	c.1132C>T	p.Q378*	COSMIC	NP	NP
152	TCGA-G4-6588-01	Tumour	LARGE INTESTINE	ENST00000216274	c.309G>A	p.S103S	COSMIC	NP	NP
153	TCGA-G4-6626-01	Tumour	LARGE INTESTINE	ENST00000216274	c.110G>T	p.R37L	COSMIC	NP	NP
154	TCGA-G9-6356-01	Tumour	PROSTATE	ENST00000216274	c.304T>C	p.L102L	COSMIC	NP	NP
155	cSCCP6	Tumour	SKIN	ENST00000216274	c.967G>A	p.G323R	COSMIC	NP	NP
156	tumor	Tumour	4163639 HAEMATOPOIETIC AND LYMPHOID TISSUE	ENST00000216274	c.448C>T	p.L150L	COSMIC	NP	NP
157	AN3CA	Cell Line	ENDOMETRIUM	ENST00000216274	c.1315C>T	p.P439S	COSMIC	PASSENGER/OTHER	BENIGN
158	BFTC909	Cell Line	KIDNEY	ENST00000216274	c.1173G>A	p.S391S	COSMIC	NP	NP
159	DG75	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000216274	c.1469_1470insC	p.P493fs*9	COSMIC	NP	NP
160	HCT116	Cell Line	LARGE_INTESTINE	ENST00000216274	c.308C>T	p.S103L	COSMIC	PASSENGER/OTHER	BENIGN
161	JHU022	Cell Line	UPPER_AERODIGESTIVE_TRACT	ENST00000216274	c.621C>T	p.F207F	COSMIC	NP	NP
162	JHU022	Cell Line	UPPER_AERODIGESTIVE_TRACT	ENST00000216274	c.832G>T	p.E278*	COSMIC	NP	NP
163	KYSE150	Cell Line	OESOPHAGUS	ENST00000216274	c.142G>A	p.A48T	COSMIC	CANCER	PROBABLY DAMAGING
164	KYSE180	Cell Line	OESOPHAGUS	ENST00000216274	c.1099A>T	p.S367C	COSMIC	CANCER	PROBABLY DAMAGING
165	LOVO	Cell Line	LARGE_INTESTINE	ENST00000216274	c.1475delC	p.P492fs*3	COSMIC	NP	NP
166	LOVO	Cell Line	LARGE_INTESTINE	ENST00000216274	c.466G>A	p.V156I	COSMIC	CANCER	BENIGN
167	LS180	Cell Line	LARGE_INTESTINE	ENST00000216274	c.1301G>C	p.W434S	COSMIC	PASSENGER/OTHER	BENIGN
168	MELHO	Cell Line	SKIN	ENST00000216274	c.1284G>C	p.E428D	COSMIC	PASSENGER/OTHER	BENIGN
169	MFE319	Cell Line	ENDOMETRIUM	ENST00000216274	c.1497C>T	p.G499G	COSMIC	NP	NP
170	MOLT4	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000216274	c.1339C>T	p.R447*	COSMIC	NP	NP
171	NCCIT	Cell Line	TESTIS	ENST00000216274	c.1074C>T	p.P358P	COSMIC	NP	NP
172	NCIH1755	Cell Line	LUNG	ENST00000216274	c.1549G>A	p.G517R	COSMIC	CANCER	BENIGN
173	NCIH2085	Cell Line	LUNG	ENST00000216274	c.958T>C	p.S320P	COSMIC	CANCER	BENIGN
174	NCIH929	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000216274	c.1518G>A	p.W506*	COSMIC	NP	NP
175	OC314	Cell Line	OVARY	ENST00000216274	c.163A>T	p.K55*	COSMIC	NP	NP
176	RCHACV	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000216274	c.1429T>C	p.W477R	COSMIC	PASSENGER/OTHER	BENIGN
177	RCHACV	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000216274	c.345G>A	p.P115P	COSMIC	NP	NP
178	RCK8	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000216274	c.1261C>T	p.P421S	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
179	RCK8	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000216274	c.396C>T	p.H132H	COSMIC	NP	NP
180	RPMI8402	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000216274	c.1054C>T	p.L352L	COSMIC	NP	NP
181	SKMG1	Cell Line	CENTRAL_NERVOUS_SYSTEM	ENST00000216274	c.1411A>G	p.T471A	COSMIC	PASSENGER/OTHER	BENIGN
182	SNUC1	Cell Line	LARGE_INTESTINE	ENST00000216274	c.1348G>A	p.V450I	COSMIC	PASSENGER/OTHER	BENIGN
183	TGBC11TKB	Cell Line	STOMACH	ENST00000216274	c.760G>A	p.G254S	COSMIC	CANCER	PROBABLY DAMAGING
184	VMRCMELG	Cell Line	SKIN	ENST00000216274	c.1054C>T	p.L352L	COSMIC	NP	NP

*NP: Not Predicted

Tissue Type	Mean Expression Value	Median Expression Value	Mean CNV	Median CNV

AUTONOMIC GANGLIA	4.7252	4.7453	-0.0418	-0.0559
BILIARY TRACT	5.7156	5.8715	0.2328	0.3755
BONE	5.1270	4.9206	-0.0887	-0.0098
BREAST	5.2433	5.028	0.0005	0.0013015
CENTRAL NERVOUS SYSTEM	4.8639	4.8801	-0.2915	-0.2048
ENDOMETRIUM	5.0417	4.8992	0.0211	0.0057
HAEMATOPOIETIC AND LYMPHOID TISSUE	5.7518	5.6785	-0.0738	-0.00799
KIDNEY	4.7036	4.791	-0.5674	-0.6919
LARGE INTESTINE	6.3022	6.38075	-0.0079	-0.0107105
LIVER	4.8838	4.8647	0.1172	0.06334
LUNG	5.1117	4.9328	0.1321	0.15165
OESOPHAGUS	5.3617	5.06905	0.0564	-0.09825
OVARY	5.1916	4.9584	-0.0045	0.02578
PANCREAS	5.8724	5.8276	-0.0208	0.1002
PLEURA	4.9427	4.8306	-0.1265	2e-04
PROSTATE	4.7940	4.8067	0.0095	0.021165
SALIVARY GLAND	5.7495	5.7495	-0.0549	-0.0549
SKIN	4.9911	4.9244	-0.1269	-0.04398
SMALL INTESTINE	5.0559	5.0559	0.0197	0.0197
SOFT TISSUE	4.8580	4.88805	0.1499	0.029445
STOMACH	5.6255	5.2959	0.0436	-0.0222
THYROID	4.7723	4.77395	0.2179	0.1116
UPPER AERODIGESTIVE TRACT	5.2086	5.14885	0.0957	0.08638
URINARY TRACT	5.4505	5.2266	0.0844	0.040345

Domain ID	Domain Name	Start Site	End Site	E-value
PF00069	Pkinase	22	280	1.5e-46
PF12721	RHIM	417	469	4.3e-14
PF00069	Pkinase	22	280	1.5e-46
PF12721	RHIM	417	469	4.3e-14

Domain ID	Start Site	End Site	E-value
0040727	16	294	2.83e-63
0040727	16	294	2.83e-63

S. No.	Position	Amino acid	Type	Description
1	199	S	Phosphorylation	Phosphoserine; by autocatalysis.
2	227	S	Phosphorylation	Phosphoserine
3	199	S	Phosphorylation	Phosphoserine; by autocatalysis.
4	227	S	Phosphorylation	Phosphoserine

Proteomics DB	COSMIC	Gene Atlas	STRING	PIR
RIPK3	RIPK3	RIPK3	ENSP00000216274	Q9Y572
QuickGO	HGNC	Ensembl Genome Browser	TreeFam	UniProt
Q9Y572	RIPK3	ENSP00000216274	RIPK3	Q9Y572
Expression Atlas	Protein Atlas	OMIM	IntAct	PharmGKB
RIPK3	ENSP00000216274	605817	Q9Y572	PA34396

Protein: RIPK3

Mutation Data (+)

Copy number variation and expression profile (+)

Gene Essentiality Data (+)

Tertiary structure (+)

Structure Domains (+)

Sequence Alignment (+)

Sequence Profiles (+)

Post Translational Modifications (+)

Other Databases Link (+)

Modelled Structure	Structures available in PDB
	Structure is not available in PDB