ApoCanD

#	Name/ID	Cell Line/Tumor sample	Tissue of Origin	Reference ID	cDNA change	Protein change	Source	FATHMM Prediction	PolyPhen2 Prediction
1	769P	Cell Line	KIDNEY	NP_620635	c.1218G>A	p.P406P	CCLE	NP	NP
2	BICR18	Cell Line	UPPER AERODIGESTIVE TRACT	NP_620635	c.1230T>G	p.S410S	CCLE	NP	NP
3	BICR18	Cell Line	UPPER AERODIGESTIVE TRACT	NP_620635	c.1263G>A	p.G421G	CCLE	NP	NP
4	CHL1	Cell Line	SKIN	NP_620635	c.1225G>T	p.A409S	CCLE	CANCER	Benign
5	CW2	Cell Line	LARGE INTESTINE	NP_620635	c.236G>A	p.C79Y	CCLE	PASSENGER/OTHER	Benign
6	EN	Cell Line	ENDOMETRIUM	NP_620635	c.912A>G	p.I304M	CCLE	CANCER	Benign
7	HEC251	Cell Line	ENDOMETRIUM	NP_620635	c.563C>A	p.T188N	CCLE	CANCER	Possibly Damaging
8	HEC6	Cell Line	ENDOMETRIUM	NP_620635	c.205C>T	p.R69W	CCLE	PASSENGER/OTHER	Probably Damaging
9	HEC6	Cell Line	ENDOMETRIUM	NP_620635	c.916G>A	p.A306T	CCLE	CANCER	Benign
10	HSC3	Cell Line	UPPER AERODIGESTIVE TRACT	NP_620635	c.307G>C	p.D103H	CCLE	PASSENGER/OTHER	Probably Damaging
11	HT55	Cell Line	LARGE INTESTINE	NP_620635	c.830A>T	p.D277V	CCLE	CANCER	Probably Damaging
12	HUNS1	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_620635	c.830A>T	p.D277V	CCLE	CANCER	Probably Damaging
13	KELLY	Cell Line	AUTONOMIC GANGLIA	NP_620635	c.845C>A	p.A282D	CCLE	CANCER	Benign
14	NCIH1581	Cell Line	LUNG	NP_620635	c.469A>G	p.I157V	CCLE	CANCER	Possibly Damaging
15	NCIH2342	Cell Line	LUNG	NP_620635	c.776A>T	p.Y259F	CCLE	CANCER	Possibly Damaging
16	NCIH596	Cell Line	LUNG	NP_620635	c.335A>G	p.D112G	CCLE	CANCER	Probably Damaging
17	NUGC3	Cell Line	STOMACH	NP_620635	c.529G>T	p.G177*	CCLE	NP	NP
18	OC316	Cell Line	OVARY	NP_620635	c.599T>C	p.M200T	CCLE	PASSENGER/OTHER	Benign
19	RT4	Cell Line	URINARY TRACT	NP_620635	c.446A>G	p.H149R	CCLE	CANCER	Probably Damaging
20	SW1271	Cell Line	LUNG	NP_620635	c.830A>G	p.D277G	CCLE	CANCER	Probably Damaging
21	UACC812	Cell Line	BREAST	NP_620635	c.668T>C	p.V223A	CCLE	NP	NP
22	UT7	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_620635	c.16C>A	p.R6S	CCLE	CANCER	Benign
23	112503	Tumour	LUNG	ENST00000374182	c.431C>T	p.S144F	COSMIC	NP	NP
24	16686	Tumour	LUNG	ENST00000374182	c.358C>T	p.Q120*	COSMIC	NP	NP
25	587364	Tumour	LARGE INTESTINE	ENST00000374182	c.565C>G	p.R189G	COSMIC	NP	NP
26	CHC614T	Tumour	LIVER	ENST00000374182	c.74G>A	p.R25Q	COSMIC	NP	NP
27	CLL001	Tumour	HAEMATOPOIETIC AND LYMPHOID TISSUE	ENST00000374182	c.739G>A	p.E247K	COSMIC	NP	NP
28	ESO-1060	Tumour	OESOPHAGUS	ENST00000374182	c.205C>T	p.R69W	COSMIC	NP	NP
29	LUAD-CHTN-MAD06-00668	Tumour	LUNG	ENST00000374182	c.72A>G	p.K24K	COSMIC	NP	NP
30	LUAD-RT-S01831	Tumour	LUNG	ENST00000374182	c.207G>T	p.R69R	COSMIC	NP	NP
31	N87	Cell Line	STOMACH	ENST00000374182	c.739G>T	p.E247*	COSMIC	NP	NP
32	P48	Tumour	LIVER	ENST00000374182	c.247A>T	p.K83*	COSMIC	NP	NP
33	PD1487a	Tumour	CENTRAL NERVOUS SYSTEM	ENST00000374182	c.529G>A	p.G177R	COSMIC	NP	NP
34	PD1757a	Tumour	KIDNEY	ENST00000374182	c.511G>A	p.G171S	COSMIC	NP	NP
35	TCGA-02-0028-01	Tumour	CENTRAL NERVOUS SYSTEM	ENST00000374182	c.549G>A	p.T183T	COSMIC	NP	NP
36	TCGA-02-0064-01	Tumour	CENTRAL NERVOUS SYSTEM	ENST00000374182	c.582C>T	p.P194P	COSMIC	NP	NP
37	TCGA-05-4403-01	Tumour	LUNG	ENST00000374182	c.906G>T	p.L302L	COSMIC	NP	NP
38	TCGA-21-5787-01	Tumour	LUNG	ENST00000374182	c.445C>T	p.H149Y	COSMIC	NP	NP
39	TCGA-61-1998-01	Tumour	OVARY	ENST00000374182	c.592C>T	p.L198F	COSMIC	NP	NP
40	TCGA-66-2787-01	Tumour	LUNG	ENST00000374182	c.565C>T	p.R189C	COSMIC	NP	NP
41	TCGA-66-2787-01	Tumour	LUNG	ENST00000374182	c.566G>T	p.R189L	COSMIC	NP	NP
42	TCGA-A5-A0GP-01	Tumour	ENDOMETRIUM	ENST00000374182	c.303T>G	p.F101L	COSMIC	NP	NP
43	TCGA-A6-5665-01	Tumour	LARGE INTESTINE	ENST00000374182	c.548C>T	p.T183M	COSMIC	NP	NP
44	TCGA-A7-A0D9-01	Tumour	BREAST	ENST00000374182	c.73C>T	p.R25*	COSMIC	NP	NP
45	TCGA-A8-A094-01	Tumour	BREAST	ENST00000374182	c.448C>T	p.R150W	COSMIC	NP	NP
46	TCGA-AA-3877-01	Tumour	LARGE INTESTINE	ENST00000374182	c.691A>G	p.I231V	COSMIC	NP	NP
47	TCGA-AA-3950-01	Tumour	LARGE INTESTINE	ENST00000374182	c.582C>A	p.P194P	COSMIC	NP	NP
48	TCGA-AA-A01Q-01	Tumour	LARGE INTESTINE	ENST00000374182	c.302T>C	p.F101S	COSMIC	NP	NP
49	TCGA-AD-6889-01	Tumour	LARGE INTESTINE	ENST00000374182	c.1021C>T	p.Q341*	COSMIC	NP	NP
50	TCGA-AG-3892-01	Tumour	LARGE INTESTINE	ENST00000374182	c.343C>A	p.L115I	COSMIC	NP	NP
51	TCGA-AG-A002-01	Tumour	LARGE INTESTINE	ENST00000374182	c.307G>T	p.D103Y	COSMIC	NP	NP
52	TCGA-AG-A002-01	Tumour	LARGE INTESTINE	ENST00000374182	c.959A>G	p.Y320C	COSMIC	NP	NP
53	TCGA-AG-A02N-01	Tumour	LARGE INTESTINE	ENST00000374182	c.16C>T	p.R6C	COSMIC	NP	NP
54	TCGA-AP-A051-01	Tumour	ENDOMETRIUM	ENST00000374182	c.123C>T	p.C41C	COSMIC	NP	NP
55	TCGA-AP-A056-01	Tumour	ENDOMETRIUM	ENST00000374182	c.302T>C	p.F101S	COSMIC	NP	NP
56	TCGA-AP-A059-01	Tumour	ENDOMETRIUM	ENST00000374182	c.92C>T	p.P31L	COSMIC	NP	NP
57	TCGA-AP-A0LF-01	Tumour	ENDOMETRIUM	ENST00000374182	c.649G>C	p.E217Q	COSMIC	NP	NP
58	TCGA-AU-3779-01	Tumour	LARGE INTESTINE	ENST00000374182	c.112G>C	p.G38R	COSMIC	NP	NP
59	TCGA-AU-3779-01	Tumour	LARGE INTESTINE	ENST00000374182	c.360G>T	p.Q120H	COSMIC	NP	NP
60	TCGA-AY-6386-01	Tumour	LARGE INTESTINE	ENST00000374182	c.513T>C	p.G171G	COSMIC	NP	NP
61	TCGA-AZ-4315-01	Tumour	LARGE INTESTINE	ENST00000374182	c.138C>T	p.A46A	COSMIC	NP	NP
62	TCGA-AZ-4323-01	Tumour	LARGE INTESTINE	ENST00000374182	c.359A>G	p.Q120R	COSMIC	NP	NP
63	TCGA-AZ-6598-01	Tumour	LARGE INTESTINE	ENST00000374182	c.513T>C	p.G171G	COSMIC	NP	NP
64	TCGA-AZ-6601-01	Tumour	LARGE INTESTINE	ENST00000374182	c.778G>A	p.V260I	COSMIC	NP	NP
65	TCGA-B5-A0JR-01	Tumour	ENDOMETRIUM	ENST00000374182	c.548C>T	p.T183M	COSMIC	NP	NP
66	TCGA-B5-A0JY-01	Tumour	ENDOMETRIUM	ENST00000374182	c.343C>A	p.L115I	COSMIC	NP	NP
67	TCGA-BK-A0C9-01	Tumour	ENDOMETRIUM	ENST00000374182	c.997-1G>A	p.?	COSMIC	NP	NP
68	TCGA-BS-A0UV-01	Tumour	ENDOMETRIUM	ENST00000374182	c.1061-1G>T	p.?	COSMIC	NP	NP
69	TCGA-BT-A20U-01	Tumour	URINARY TRACT	ENST00000374182	c.739G>C	p.E247Q	COSMIC	NP	NP
70	TCGA-BT-A20U-01	Tumour	URINARY TRACT	ENST00000374182	c.847G>C	p.D283H	COSMIC	NP	NP
71	TCGA-CL-5918-01	Tumour	LARGE INTESTINE	ENST00000374182	c.547A>G	p.T183A	COSMIC	NP	NP
72	TCGA-CM-4743-01	Tumour	LARGE INTESTINE	ENST00000374182	c.124G>A	p.A42T	COSMIC	NP	NP
73	TCGA-CM-4743-01	Tumour	LARGE INTESTINE	ENST00000374182	c.531A>G	p.G177G	COSMIC	NP	NP
74	TCGA-CM-5349-01	Tumour	LARGE INTESTINE	ENST00000374182	c.530G>T	p.G177V	COSMIC	NP	NP
75	TCGA-D1-A101-01	Tumour	ENDOMETRIUM	ENST00000374182	c.566G>A	p.R189H	COSMIC	NP	NP
76	TCGA-D1-A17Q-01	Tumour	ENDOMETRIUM	ENST00000374182	c.217G>T	p.E73*	COSMIC	NP	NP
77	TCGA-D5-6540-01	Tumour	LARGE INTESTINE	ENST00000374182	c.594T>C	p.L198L	COSMIC	NP	NP
78	TCGA-D5-6930-01	Tumour	LARGE INTESTINE	ENST00000374182	c.549G>A	p.T183T	COSMIC	NP	NP
79	TCGA-DM-A1DB-01	Tumour	LARGE INTESTINE	ENST00000374182	c.582C>A	p.P194P	COSMIC	NP	NP
80	TCGA-F4-6570-01	Tumour	LARGE INTESTINE	ENST00000374182	c.231G>T	p.M77I	COSMIC	NP	NP
81	TCGA-F4-6570-01	Tumour	LARGE INTESTINE	ENST00000374182	c.360G>A	p.Q120Q	COSMIC	NP	NP
82	TCGA-H4-A2HQ-01	Tumour	URINARY TRACT	ENST00000374182	c.737C>G	p.P246R	COSMIC	NP	NP
83	YUGOE	Tumour	SKIN	ENST00000374182	c.1138+2T>C	p.?	COSMIC	NP	NP
84	YULAN	Tumour	SKIN	ENST00000374182	c.290C>T	p.S97F	COSMIC	NP	NP
85	cSCCP4	Tumour	SKIN	ENST00000374182	c.343C>T	p.L115F	COSMIC	NP	NP
86	CW2	Cell Line	LARGE_INTESTINE	ENST00000374182	c.236G>A	p.C79Y	COSMIC	PASSENGER/OTHER	BENIGN
87	EN	Cell Line	ENDOMETRIUM	ENST00000374182	c.912A>G	p.I304M	COSMIC	CANCER	BENIGN
88	HT55	Cell Line	LARGE_INTESTINE	ENST00000374182	c.830A>T	p.D277V	COSMIC	CANCER	PROBABLY DAMAGING
89	JHH4	Cell Line	LIVER	ENST00000374182	c.1095G>A	p.E365E	COSMIC	NP	NP
90	KELLY	Cell Line	AUTONOMIC_GANGLIA	ENST00000374182	c.845C>A	p.A282D	COSMIC	CANCER	BENIGN
91	NCIH1581	Cell Line	LUNG	ENST00000374182	c.469A>G	p.I157V	COSMIC	CANCER	POSSIBLY DAMAGING
92	NCIH2135	Cell Line	LUNG	ENST00000374182	c.123-6T>C	p.?	COSMIC	NP	NP
93	NCIH2342	Cell Line	LUNG	ENST00000374182	c.776A>T	p.Y259F	COSMIC	CANCER	POSSIBLY DAMAGING
94	NCIH596	Cell Line	LUNG	ENST00000374182	c.335A>G	p.D112G	COSMIC	CANCER	PROBABLY DAMAGING
95	NCIH630	Cell Line	LARGE_INTESTINE	ENST00000374182	c.262C>A	p.L88I	COSMIC	CANCER	POSSIBLY DAMAGING
96	NUGC3	Cell Line	STOMACH	ENST00000374182	c.529G>T	p.G177*	COSMIC	NP	NP
97	OC314	Cell Line	OVARY	ENST00000374182	c.599T>C	p.M200T	COSMIC	PASSENGER/OTHER	BENIGN
98	RT4	Cell Line	URINARY_TRACT	ENST00000374182	c.446A>G	p.H149R	COSMIC	CANCER	PROBABLY DAMAGING
99	SKHEP1	Cell Line	LIVER	ENST00000374182	c.48A>G	p.G16G	COSMIC	NP	NP
100	SNU1040	Cell Line	LARGE_INTESTINE	ENST00000374182	c.240T>C	p.V80V	COSMIC	NP	NP
101	SW156	Cell Line	KIDNEY	ENST00000374182	c.122+7G>T	p.?	COSMIC	NP	NP
102	769P	Cell Line	KIDNEY	NP_620635	c.1218G>A	p.P406P	CCLE	NP	NP
103	BICR18	Cell Line	UPPER AERODIGESTIVE TRACT	NP_620635	c.1230T>G	p.S410S	CCLE	NP	NP
104	BICR18	Cell Line	UPPER AERODIGESTIVE TRACT	NP_620635	c.1263G>A	p.G421G	CCLE	NP	NP
105	CHL1	Cell Line	SKIN	NP_620635	c.1225G>T	p.A409S	CCLE	CANCER	Benign
106	CW2	Cell Line	LARGE INTESTINE	NP_620635	c.236G>A	p.C79Y	CCLE	PASSENGER/OTHER	Benign
107	EN	Cell Line	ENDOMETRIUM	NP_620635	c.912A>G	p.I304M	CCLE	CANCER	Benign
108	HEC251	Cell Line	ENDOMETRIUM	NP_620635	c.563C>A	p.T188N	CCLE	CANCER	Possibly Damaging
109	HEC6	Cell Line	ENDOMETRIUM	NP_620635	c.205C>T	p.R69W	CCLE	PASSENGER/OTHER	Probably Damaging
110	HEC6	Cell Line	ENDOMETRIUM	NP_620635	c.916G>A	p.A306T	CCLE	CANCER	Benign
111	HSC3	Cell Line	UPPER AERODIGESTIVE TRACT	NP_620635	c.307G>C	p.D103H	CCLE	PASSENGER/OTHER	Probably Damaging
112	HT55	Cell Line	LARGE INTESTINE	NP_620635	c.830A>T	p.D277V	CCLE	CANCER	Probably Damaging
113	HUNS1	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_620635	c.830A>T	p.D277V	CCLE	CANCER	Probably Damaging
114	KELLY	Cell Line	AUTONOMIC GANGLIA	NP_620635	c.845C>A	p.A282D	CCLE	CANCER	Benign
115	NCIH1581	Cell Line	LUNG	NP_620635	c.469A>G	p.I157V	CCLE	CANCER	Possibly Damaging
116	NCIH2342	Cell Line	LUNG	NP_620635	c.776A>T	p.Y259F	CCLE	CANCER	Possibly Damaging
117	NCIH596	Cell Line	LUNG	NP_620635	c.335A>G	p.D112G	CCLE	CANCER	Probably Damaging
118	NUGC3	Cell Line	STOMACH	NP_620635	c.529G>T	p.G177*	CCLE	NP	NP
119	OC316	Cell Line	OVARY	NP_620635	c.599T>C	p.M200T	CCLE	PASSENGER/OTHER	Benign
120	RT4	Cell Line	URINARY TRACT	NP_620635	c.446A>G	p.H149R	CCLE	CANCER	Probably Damaging
121	SW1271	Cell Line	LUNG	NP_620635	c.830A>G	p.D277G	CCLE	CANCER	Probably Damaging
122	UACC812	Cell Line	BREAST	NP_620635	c.668T>C	p.V223A	CCLE	NP	NP
123	UT7	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_620635	c.16C>A	p.R6S	CCLE	CANCER	Benign
124	112503	Tumour	LUNG	ENST00000374182	c.431C>T	p.S144F	COSMIC	NP	NP
125	16686	Tumour	LUNG	ENST00000374182	c.358C>T	p.Q120*	COSMIC	NP	NP
126	587364	Tumour	LARGE INTESTINE	ENST00000374182	c.565C>G	p.R189G	COSMIC	NP	NP
127	CHC614T	Tumour	LIVER	ENST00000374182	c.74G>A	p.R25Q	COSMIC	NP	NP
128	CLL001	Tumour	HAEMATOPOIETIC AND LYMPHOID TISSUE	ENST00000374182	c.739G>A	p.E247K	COSMIC	NP	NP
129	ESO-1060	Tumour	OESOPHAGUS	ENST00000374182	c.205C>T	p.R69W	COSMIC	NP	NP
130	LUAD-CHTN-MAD06-00668	Tumour	LUNG	ENST00000374182	c.72A>G	p.K24K	COSMIC	NP	NP
131	LUAD-RT-S01831	Tumour	LUNG	ENST00000374182	c.207G>T	p.R69R	COSMIC	NP	NP
132	N87	Cell Line	STOMACH	ENST00000374182	c.739G>T	p.E247*	COSMIC	NP	NP
133	P48	Tumour	LIVER	ENST00000374182	c.247A>T	p.K83*	COSMIC	NP	NP
134	PD1487a	Tumour	CENTRAL NERVOUS SYSTEM	ENST00000374182	c.529G>A	p.G177R	COSMIC	NP	NP
135	PD1757a	Tumour	KIDNEY	ENST00000374182	c.511G>A	p.G171S	COSMIC	NP	NP
136	TCGA-02-0028-01	Tumour	CENTRAL NERVOUS SYSTEM	ENST00000374182	c.549G>A	p.T183T	COSMIC	NP	NP
137	TCGA-02-0064-01	Tumour	CENTRAL NERVOUS SYSTEM	ENST00000374182	c.582C>T	p.P194P	COSMIC	NP	NP
138	TCGA-05-4403-01	Tumour	LUNG	ENST00000374182	c.906G>T	p.L302L	COSMIC	NP	NP
139	TCGA-21-5787-01	Tumour	LUNG	ENST00000374182	c.445C>T	p.H149Y	COSMIC	NP	NP
140	TCGA-61-1998-01	Tumour	OVARY	ENST00000374182	c.592C>T	p.L198F	COSMIC	NP	NP
141	TCGA-66-2787-01	Tumour	LUNG	ENST00000374182	c.565C>T	p.R189C	COSMIC	NP	NP
142	TCGA-66-2787-01	Tumour	LUNG	ENST00000374182	c.566G>T	p.R189L	COSMIC	NP	NP
143	TCGA-A5-A0GP-01	Tumour	ENDOMETRIUM	ENST00000374182	c.303T>G	p.F101L	COSMIC	NP	NP
144	TCGA-A6-5665-01	Tumour	LARGE INTESTINE	ENST00000374182	c.548C>T	p.T183M	COSMIC	NP	NP
145	TCGA-A7-A0D9-01	Tumour	BREAST	ENST00000374182	c.73C>T	p.R25*	COSMIC	NP	NP
146	TCGA-A8-A094-01	Tumour	BREAST	ENST00000374182	c.448C>T	p.R150W	COSMIC	NP	NP
147	TCGA-AA-3877-01	Tumour	LARGE INTESTINE	ENST00000374182	c.691A>G	p.I231V	COSMIC	NP	NP
148	TCGA-AA-3950-01	Tumour	LARGE INTESTINE	ENST00000374182	c.582C>A	p.P194P	COSMIC	NP	NP
149	TCGA-AA-A01Q-01	Tumour	LARGE INTESTINE	ENST00000374182	c.302T>C	p.F101S	COSMIC	NP	NP
150	TCGA-AD-6889-01	Tumour	LARGE INTESTINE	ENST00000374182	c.1021C>T	p.Q341*	COSMIC	NP	NP
151	TCGA-AG-3892-01	Tumour	LARGE INTESTINE	ENST00000374182	c.343C>A	p.L115I	COSMIC	NP	NP
152	TCGA-AG-A002-01	Tumour	LARGE INTESTINE	ENST00000374182	c.307G>T	p.D103Y	COSMIC	NP	NP
153	TCGA-AG-A002-01	Tumour	LARGE INTESTINE	ENST00000374182	c.959A>G	p.Y320C	COSMIC	NP	NP
154	TCGA-AG-A02N-01	Tumour	LARGE INTESTINE	ENST00000374182	c.16C>T	p.R6C	COSMIC	NP	NP
155	TCGA-AP-A051-01	Tumour	ENDOMETRIUM	ENST00000374182	c.123C>T	p.C41C	COSMIC	NP	NP
156	TCGA-AP-A056-01	Tumour	ENDOMETRIUM	ENST00000374182	c.302T>C	p.F101S	COSMIC	NP	NP
157	TCGA-AP-A059-01	Tumour	ENDOMETRIUM	ENST00000374182	c.92C>T	p.P31L	COSMIC	NP	NP
158	TCGA-AP-A0LF-01	Tumour	ENDOMETRIUM	ENST00000374182	c.649G>C	p.E217Q	COSMIC	NP	NP
159	TCGA-AU-3779-01	Tumour	LARGE INTESTINE	ENST00000374182	c.112G>C	p.G38R	COSMIC	NP	NP
160	TCGA-AU-3779-01	Tumour	LARGE INTESTINE	ENST00000374182	c.360G>T	p.Q120H	COSMIC	NP	NP
161	TCGA-AY-6386-01	Tumour	LARGE INTESTINE	ENST00000374182	c.513T>C	p.G171G	COSMIC	NP	NP
162	TCGA-AZ-4315-01	Tumour	LARGE INTESTINE	ENST00000374182	c.138C>T	p.A46A	COSMIC	NP	NP
163	TCGA-AZ-4323-01	Tumour	LARGE INTESTINE	ENST00000374182	c.359A>G	p.Q120R	COSMIC	NP	NP
164	TCGA-AZ-6598-01	Tumour	LARGE INTESTINE	ENST00000374182	c.513T>C	p.G171G	COSMIC	NP	NP
165	TCGA-AZ-6601-01	Tumour	LARGE INTESTINE	ENST00000374182	c.778G>A	p.V260I	COSMIC	NP	NP
166	TCGA-B5-A0JR-01	Tumour	ENDOMETRIUM	ENST00000374182	c.548C>T	p.T183M	COSMIC	NP	NP
167	TCGA-B5-A0JY-01	Tumour	ENDOMETRIUM	ENST00000374182	c.343C>A	p.L115I	COSMIC	NP	NP
168	TCGA-BK-A0C9-01	Tumour	ENDOMETRIUM	ENST00000374182	c.997-1G>A	p.?	COSMIC	NP	NP
169	TCGA-BS-A0UV-01	Tumour	ENDOMETRIUM	ENST00000374182	c.1061-1G>T	p.?	COSMIC	NP	NP
170	TCGA-BT-A20U-01	Tumour	URINARY TRACT	ENST00000374182	c.739G>C	p.E247Q	COSMIC	NP	NP
171	TCGA-BT-A20U-01	Tumour	URINARY TRACT	ENST00000374182	c.847G>C	p.D283H	COSMIC	NP	NP
172	TCGA-CL-5918-01	Tumour	LARGE INTESTINE	ENST00000374182	c.547A>G	p.T183A	COSMIC	NP	NP
173	TCGA-CM-4743-01	Tumour	LARGE INTESTINE	ENST00000374182	c.124G>A	p.A42T	COSMIC	NP	NP
174	TCGA-CM-4743-01	Tumour	LARGE INTESTINE	ENST00000374182	c.531A>G	p.G177G	COSMIC	NP	NP
175	TCGA-CM-5349-01	Tumour	LARGE INTESTINE	ENST00000374182	c.530G>T	p.G177V	COSMIC	NP	NP
176	TCGA-D1-A101-01	Tumour	ENDOMETRIUM	ENST00000374182	c.566G>A	p.R189H	COSMIC	NP	NP
177	TCGA-D1-A17Q-01	Tumour	ENDOMETRIUM	ENST00000374182	c.217G>T	p.E73*	COSMIC	NP	NP
178	TCGA-D5-6540-01	Tumour	LARGE INTESTINE	ENST00000374182	c.594T>C	p.L198L	COSMIC	NP	NP
179	TCGA-D5-6930-01	Tumour	LARGE INTESTINE	ENST00000374182	c.549G>A	p.T183T	COSMIC	NP	NP
180	TCGA-DM-A1DB-01	Tumour	LARGE INTESTINE	ENST00000374182	c.582C>A	p.P194P	COSMIC	NP	NP
181	TCGA-F4-6570-01	Tumour	LARGE INTESTINE	ENST00000374182	c.231G>T	p.M77I	COSMIC	NP	NP
182	TCGA-F4-6570-01	Tumour	LARGE INTESTINE	ENST00000374182	c.360G>A	p.Q120Q	COSMIC	NP	NP
183	TCGA-H4-A2HQ-01	Tumour	URINARY TRACT	ENST00000374182	c.737C>G	p.P246R	COSMIC	NP	NP
184	YUGOE	Tumour	SKIN	ENST00000374182	c.1138+2T>C	p.?	COSMIC	NP	NP
185	YULAN	Tumour	SKIN	ENST00000374182	c.290C>T	p.S97F	COSMIC	NP	NP
186	cSCCP4	Tumour	SKIN	ENST00000374182	c.343C>T	p.L115F	COSMIC	NP	NP
187	CW2	Cell Line	LARGE_INTESTINE	ENST00000374182	c.236G>A	p.C79Y	COSMIC	PASSENGER/OTHER	BENIGN
188	EN	Cell Line	ENDOMETRIUM	ENST00000374182	c.912A>G	p.I304M	COSMIC	CANCER	BENIGN
189	HT55	Cell Line	LARGE_INTESTINE	ENST00000374182	c.830A>T	p.D277V	COSMIC	CANCER	PROBABLY DAMAGING
190	JHH4	Cell Line	LIVER	ENST00000374182	c.1095G>A	p.E365E	COSMIC	NP	NP
191	KELLY	Cell Line	AUTONOMIC_GANGLIA	ENST00000374182	c.845C>A	p.A282D	COSMIC	CANCER	BENIGN
192	NCIH1581	Cell Line	LUNG	ENST00000374182	c.469A>G	p.I157V	COSMIC	CANCER	POSSIBLY DAMAGING
193	NCIH2135	Cell Line	LUNG	ENST00000374182	c.123-6T>C	p.?	COSMIC	NP	NP
194	NCIH2342	Cell Line	LUNG	ENST00000374182	c.776A>T	p.Y259F	COSMIC	CANCER	POSSIBLY DAMAGING
195	NCIH596	Cell Line	LUNG	ENST00000374182	c.335A>G	p.D112G	COSMIC	CANCER	PROBABLY DAMAGING
196	NCIH630	Cell Line	LARGE_INTESTINE	ENST00000374182	c.262C>A	p.L88I	COSMIC	CANCER	POSSIBLY DAMAGING
197	NUGC3	Cell Line	STOMACH	ENST00000374182	c.529G>T	p.G177*	COSMIC	NP	NP
198	OC314	Cell Line	OVARY	ENST00000374182	c.599T>C	p.M200T	COSMIC	PASSENGER/OTHER	BENIGN
199	RT4	Cell Line	URINARY_TRACT	ENST00000374182	c.446A>G	p.H149R	COSMIC	CANCER	PROBABLY DAMAGING
200	SKHEP1	Cell Line	LIVER	ENST00000374182	c.48A>G	p.G16G	COSMIC	NP	NP
201	SNU1040	Cell Line	LARGE_INTESTINE	ENST00000374182	c.240T>C	p.V80V	COSMIC	NP	NP
202	SW156	Cell Line	KIDNEY	ENST00000374182	c.122+7G>T	p.?	COSMIC	NP	NP

*NP: Not Predicted

Tissue Type	Mean Expression Value	Median Expression Value	Mean CNV	Median CNV

AUTONOMIC GANGLIA	5.5244	5.4613	-0.0006	0.01342
BILIARY TRACT	4.9939	5.0224	-0.0666	0.006931
BONE	4.8761	4.8442	-0.0892	-0.03568
BREAST	5.0921	5.0002	0.0503	0.03725
CENTRAL NERVOUS SYSTEM	4.8907	4.7262	-0.2890	-0.2487
ENDOMETRIUM	5.1398	5.0848	-0.0907	-0.0348
HAEMATOPOIETIC AND LYMPHOID TISSUE	5.2442	5.2082	-0.0769	-0.0261
KIDNEY	5.2028	5.1703	0.1257	0.083
LARGE INTESTINE	5.1388	5.10775	0.0031	-0.021915
LIVER	4.9438	4.8902	0.0709	0.1171
LUNG	5.1530	5.0943	-0.1898	-0.13845
OESOPHAGUS	4.9736	5.04025	-0.2249	-0.2852
OVARY	5.1120	5.0659	-0.0185	0.01625
PANCREAS	5.0807	5.0755	-0.0581	0.0658
PLEURA	4.7922	4.8015	-0.1179	0.0483
PROSTATE	5.4734	5.5083	-0.0535	0.02558
SALIVARY GLAND	4.6488	4.6488	-0.4460	-0.446
SKIN	4.7438	4.6727	-0.3622	-0.3405
SMALL INTESTINE	4.7113	4.7113	0.0015	0.0015
SOFT TISSUE	4.8971	4.8109	-0.0537	-0.026475
STOMACH	4.9473	4.85805	-0.0798	-0.0978
THYROID	5.4514	5.3604	-0.0154	0.0124
UPPER AERODIGESTIVE TRACT	4.9315	4.8366	-0.1284	-0.03785
URINARY TRACT	5.3100	5.2949	-0.0968	-0.028

Domain ID	Domain Name	Start Site	End Site	E-value
PF00069	Pkinase	26	321	6.3e-66
PF00069	Pkinase	26	321	6.3e-66

Domain ID	Start Site	End Site	E-value
0051877	12	357	7.59e-94
0051877	12	357	7.59e-94

Proteomics DB	COSMIC	Gene Atlas	STRING	PIR
MAPK8	MAPK8	MAPK8	ENSP00000353483	P45983
QuickGO	HGNC	Ensembl Genome Browser	TreeFam	UniProt
P45983	MAPK8	ENSP00000353483	MAPK8	P45983
Expression Atlas	Protein Atlas	OMIM	IntAct	PharmGKB
MAPK8	ENSP00000353483	601158	P45983	PA283

Protein: MAPK8

Mutation Data (+)

Copy number variation and expression profile (+)

Gene Essentiality Data (+)

Tertiary structure (+)

Structure Domains (+)

Sequence Alignment (+)

Sequence Profiles (+)

Post Translational Modifications (+)

Other Databases Link (+)

Modelled Structure	Structures available in PDB
	1UKH, 1UKI, 2G01, 2GMX, 2H96, 2NO3, 2XRW, 2XS0, 3ELJ, 3O17, 3O2M, 3PZE, 3V3V, 3VUD, 3VUG, 3VUH, 3VUI, 3VUK, 3VUL, 3VUM, 4AWI, 4E73, 4G1W, 4HYS, 4HYU, 4IZY, 4L7F