Mutation Data (+)
| # | Name/ID | Cell Line/Tumor sample | Tissue of Origin | Reference ID | cDNA change | Protein change | Source | FATHMM Prediction | PolyPhen2 Prediction |
|---|---|---|---|---|---|---|---|---|---|
| 1 | LUAD-5V8LT | Tumour | LUNG | ENST00000257572 | c.173G>A | p.R58K | COSMIC | NP | NP |
| 2 | LUAD-5V8LT | Tumour | LUNG | ENST00000257572 | c.173G>A | p.R58K | COSMIC | NP | NP |
*NP: Not Predicted
Copy number variation and expression profile (+)
Gene Essentiality Data (+)
Note: Lower the GARP score (more negative), higher the essentiality of the gene. P-value tells about the significane of GARP score.
Tertiary structure (+)
Structure Domains (+)
Sequence Alignment (+)
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1. Variants are not present in 1000 Genomes!!
2. Mutants are not present in CCLE!!
3. Sequence alignment with COSMIC mutants:
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4. Sequence alignment with homologus proteins:
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Sequence Profiles (+)
Post Translational Modifications (+)
Post translational modifications are not found!!
Other Databases Link (+)
| Proteomics DB | COSMIC | Gene Atlas | STRING | PIR |
| HRK | HRK | HRK | ENSP00000257572 | O00198 |
| QuickGO | HGNC | Ensembl Genome Browser | TreeFam | UniProt |
| O00198 | HRK | ENSP00000257572 | HRK | O00198 |
| Expression Atlas | Protein Atlas | OMIM | IntAct | PharmGKB |
| HRK | ENSP00000257572 | 603447 | O00198 | PA29459 |