ApoCanD

#	Name/ID	Cell Line/Tumor sample	Tissue of Origin	Reference ID	cDNA change	Protein change	Source	FATHMM Prediction	PolyPhen2 Prediction
1	EB2	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_000034	c.948G>A	p.K316K	CCLE	NP	NP
2	GCT	Cell Line	SOFT TISSUE	NP_000034	c.305G>A	p.R102K	CCLE	PASSENGER/OTHER	Probably Damaging
3	HEC151	Cell Line	ENDOMETRIUM	NP_000034	c.870G>A	p.A290A	CCLE	NP	NP
4	HEC59	Cell Line	ENDOMETRIUM	NP_000034	c.397_397delT	p.F133fs	CCLE	NP	NP
5	JHUEM7	Cell Line	ENDOMETRIUM	NP_000034	c.748C>T	p.R250*	CCLE	NP	NP
6	KYO1	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_000034	c.38C>T	p.T13M	CCLE	PASSENGER/OTHER	Probably Damaging
7	KYSE150	Cell Line	OESOPHAGUS	NP_000034	c.836G>A	p.R279H	CCLE	PASSENGER/OTHER	Probably Damaging
8	L1236	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_000034	c.651_splice	p.P217_splice	CCLE	NP	NP
9	LS411N	Cell Line	LARGE INTESTINE	NP_000034	c.711T>C	p.A237A	CCLE	NP	NP
10	NCIH1573	Cell Line	LUNG	NP_000034	c.495C>T	p.C165C	CCLE	NP	NP
11	NCIH1755	Cell Line	LUNG	NP_000034	c.880T>C	p.L294L	CCLE	NP	NP
12	NCIH1838	Cell Line	LUNG	NP_000034	c.799G>T	p.V267F	CCLE	PASSENGER/OTHER	Benign
13	OCILY10	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_000034	c.526T>G	p.W176G	CCLE	PASSENGER/OTHER	Probably Damaging
14	P3HR1	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_000034	c.818A>G	p.Q273R	CCLE	CANCER	Probably Damaging
15	SNU407	Cell Line	LARGE INTESTINE	NP_000034	c.176G>A	p.C59Y	CCLE	CANCER	Probably Damaging
16	SNU81	Cell Line	LARGE INTESTINE	NP_000034	c.568_splice	p.V190_splice	CCLE	NP	NP
17	SUDHL8	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_000034	c.680_684delTTGAC	p.V227fs	CCLE	NP	NP
18	06-25470	Tumour	HAEMATOPOIETIC AND LYMPHOID TISSUE	NM_000043.3	c.696T>G	p.Y232*	COSMIC	NP	NP
19	105307	Tumour	BREAST	NM_000043.3	c.381C>T	p.C127C	COSMIC	NP	NP
20	BB49-HNC	Cell Line	UPPER AERODIGESTIVE TRACT	NM_000043.3	c.805G>A	p.D269N	COSMIC	NP	NP
21	DLBCL-PatientM	Tumour	HAEMATOPOIETIC AND LYMPHOID TISSUE	NM_000043.3	c.733G>C	p.V245L	COSMIC	NP	NP
22	DLBCL-PatientM	Tumour	HAEMATOPOIETIC AND LYMPHOID TISSUE	NM_000043.3	c.794A>G	p.D265G	COSMIC	NP	NP
23	FL-PatientA	Tumour	HAEMATOPOIETIC AND LYMPHOID TISSUE	NM_000043.3	c.826C>T	p.Q276*	COSMIC	NP	NP
24	HCC137T	Tumour	LIVER	NM_000043.3	c.165T>C	p.D55D	COSMIC	NP	NP
25	HCC20T	Tumour	LIVER	NM_000043.3	c.657A>G	p.T219T	COSMIC	NP	NP
26	HCC73T	Tumour	LIVER	NM_000043.3	c.249G>C	p.V83V	COSMIC	NP	NP
27	HN	Tumour	62374 UPPER AERODIGESTIVE TRACT	NM_000043.3	c.631G>T	p.E211*	COSMIC	NP	NP
28	LUAD-5V8LT	Tumour	LUNG	NM_000043.3	c.493T>A	p.C165S	COSMIC	NP	NP
29	LUAD-NYU1021	Tumour	LUNG	NM_000043.3	c.870G>A	p.A290A	COSMIC	NP	NP
30	TCGA-18-3409-01	Tumour	LUNG	NM_000043.3	c.59C>T	p.S20F	COSMIC	NP	NP
31	TCGA-22-5472-01	Tumour	LUNG	NM_000043.3	c.474A>T	p.T158T	COSMIC	NP	NP
32	TCGA-44-6145-01	Tumour	LUNG	NM_000043.3	c.341A>T	p.E114V	COSMIC	NP	NP
33	TCGA-50-5930-01	Tumour	LUNG	NM_000043.3	c.428G>T	p.C143F	COSMIC	NP	NP
34	TCGA-95-7944-01	Tumour	LUNG	NM_000043.3	c.781G>A	p.E261K	COSMIC	NP	NP
35	TCGA-A6-6780-01	Tumour	LARGE INTESTINE	NM_000043.3	c.397delT	p.C135fs*52	COSMIC	NP	NP
36	TCGA-AD-6889-01	Tumour	LARGE INTESTINE	NM_000043.3	c.894_895insA	p.A301fs*20	COSMIC	NP	NP
37	TCGA-AG-3598-01	Tumour	LARGE INTESTINE	NM_000043.3	c.536T>A	p.L179H	COSMIC	NP	NP
38	TCGA-AG-3892-01	Tumour	LARGE INTESTINE	NM_000043.3	c.312T>C	p.C104C	COSMIC	NP	NP
39	TCGA-AG-3892-01	Tumour	LARGE INTESTINE	NM_000043.3	c.925A>C	p.K309Q	COSMIC	NP	NP
40	TCGA-AP-A051-01	Tumour	ENDOMETRIUM	NM_000043.3	c.653A>G	p.E218G	COSMIC	NP	NP
41	TCGA-AP-A051-01	Tumour	ENDOMETRIUM	NM_000043.3	c.869C>T	p.A290V	COSMIC	NP	NP
42	TCGA-AP-A056-01	Tumour	ENDOMETRIUM	NM_000043.3	c.444-1G>T	p.?	COSMIC	NP	NP
43	TCGA-AP-A059-01	Tumour	ENDOMETRIUM	NM_000043.3	c.286C>T	p.H96Y	COSMIC	NP	NP
44	TCGA-AP-A0LM-01	Tumour	ENDOMETRIUM	NM_000043.3	c.608G>T	p.R203I	COSMIC	NP	NP
45	TCGA-AX-A05Z-01	Tumour	ENDOMETRIUM	NM_000043.3	c.189T>C	p.C63C	COSMIC	NP	NP
46	TCGA-AX-A0J1-01	Tumour	ENDOMETRIUM	NM_000043.3	c.870G>A	p.A290A	COSMIC	NP	NP
47	TCGA-AZ-4315-01	Tumour	LARGE INTESTINE	NM_000043.3	c.362G>A	p.R121Q	COSMIC	NP	NP
48	TCGA-B0-5713-01	Tumour	KIDNEY	NM_000043.3	c.835C>A	p.R279S	COSMIC	NP	NP
49	TCGA-B5-A0JY-01	Tumour	ENDOMETRIUM	NM_000043.3	c.801C>A	p.V267V	COSMIC	NP	NP
50	TCGA-B5-A11E-01	Tumour	ENDOMETRIUM	NM_000043.3	c.370A>C	p.N124H	COSMIC	NP	NP
51	TCGA-B8-4154-01	Tumour	KIDNEY	NM_000043.3	c.434C>A	p.P145H	COSMIC	NP	NP
52	TCGA-BS-A0TC-01	Tumour	ENDOMETRIUM	NM_000043.3	c.559A>C	p.I187L	COSMIC	NP	NP
53	TCGA-C8-A12T-01	Tumour	BREAST	NM_000043.3	c.682G>A	p.D228N	COSMIC	NP	NP
54	TCGA-CA-6717-01	Tumour	LARGE INTESTINE	NM_000043.3	c.340G>A	p.E114K	COSMIC	NP	NP
55	TCGA-CK-4947-01	Tumour	LARGE INTESTINE	NM_000043.3	c.542T>C	p.L181P	COSMIC	NP	NP
56	TCGA-CM-5862-01	Tumour	LARGE INTESTINE	NM_000043.3	c.806A>G	p.D269G	COSMIC	NP	NP
57	TCGA-CW-5581-01	Tumour	KIDNEY	NM_000043.3	c.119C>T	p.T40I	COSMIC	NP	NP
58	TCGA-D1-A103-01	Tumour	ENDOMETRIUM	NM_000043.3	c.20T>C	p.L7P	COSMIC	NP	NP
59	TCGA-D1-A16J-01	Tumour	ENDOMETRIUM	NM_000043.3	c.503delA	p.G169fs*18	COSMIC	NP	NP
60	TCGA-D5-6927-01	Tumour	LARGE INTESTINE	NM_000043.3	c.396_397insT	p.C135fs*2	COSMIC	NP	NP
61	YUAVEY	Tumour	SKIN	NM_000043.3	c.739G>A	p.G247S	COSMIC	NP	NP
62	tumor	Tumour	4163639 HAEMATOPOIETIC AND LYMPHOID TISSUE	NM_000043.3	c.656_658CAG>C	p.V220fs*6	COSMIC	NP	NP
63	tumor	Tumour	4163639 HAEMATOPOIETIC AND LYMPHOID TISSUE	NM_000043.3	c.802C>G	p.Q268E	COSMIC	NP	NP
64	BB49HNC	Cell Line	UPPER_AERODIGESTIVE_TRACT	NM_000043.3	c.805G>A	p.D269N	COSMIC	CANCER	POSSIBLY DAMAGING
65	EB2	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	NM_000043.3	c.948G>A	p.K316K	COSMIC	NP	NP
66	GCT	Cell Line	SOFT_TISSUE	NM_000043.3	c.305G>A	p.R102K	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
67	H290	Cell Line	PLEURA	NM_000043.3	c.360C>T	p.T120T	COSMIC	NP	NP
68	JIYOYEP2003	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	NM_000043.3	c.818A>G	p.Q273R	COSMIC	CANCER	PROBABLY DAMAGING
69	KARPAS422	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	NM_000043.3	c.526T>G	p.W176G	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
70	KARPAS45	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	NM_000043.3	c.401T>C	p.F134S	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
71	KYSE150	Cell Line	OESOPHAGUS	NM_000043.3	c.836G>A	p.R279H	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
72	L1236	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	NM_000043.3	c.651+2T>C	p.?	COSMIC	NP	NP
73	LS411N	Cell Line	LARGE_INTESTINE	NM_000043.3	c.711T>C	p.A237A	COSMIC	NP	NP
74	MCC13	Cell Line	SKIN	NM_000043.3	c.293C>T	p.S98F	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
75	MRKNU1	Cell Line	BREAST	NM_000043.3	c.506-3C>T	p.?	COSMIC	NP	NP
76	NCIH1573	Cell Line	LUNG	NM_000043.3	c.495C>T	p.C165C	COSMIC	NP	NP
77	NCIH1755	Cell Line	LUNG	NM_000043.3	c.366C>T	p.T122T	COSMIC	NP	NP
78	NCIH1755	Cell Line	LUNG	NM_000043.3	c.880T>C	p.L294L	COSMIC	NP	NP
79	NCIH1770	Cell Line	LUNG	NM_000043.3	c.197-10C>T	p.?	COSMIC	NP	NP
80	NCIH1838	Cell Line	LUNG	NM_000043.3	c.799G>T	p.V267F	COSMIC	PASSENGER/OTHER	BENIGN
81	PL18	Cell Line	PANCREAS	NM_000043.3	c.937A>G	p.I313V	COSMIC	PASSENGER/OTHER	BENIGN
82	RAJI	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	NM_000043.3	c.575G>T	p.R192I	COSMIC	PASSENGER/OTHER	BENIGN
83	SNU407	Cell Line	LARGE_INTESTINE	NM_000043.3	c.176G>A	p.C59Y	COSMIC	CANCER	PROBABLY DAMAGING
84	SUDHL8	Cell Line	NS	NM_000043.3	c.57G>A	p.S19S	COSMIC	NP	NP
85	SUDHL8	Cell Line	NS	NM_000043.3	c.680_684delTTGAC	p.D228fs*2	COSMIC	NP	NP
86	SW48	Cell Line	LARGE_INTESTINE	NM_000043.3	c.315A>T	p.R105S	COSMIC	PASSENGER/OTHER	BENIGN
87	EB2	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_000034	c.948G>A	p.K316K	CCLE	NP	NP
88	GCT	Cell Line	SOFT TISSUE	NP_000034	c.305G>A	p.R102K	CCLE	PASSENGER/OTHER	Probably Damaging
89	HEC151	Cell Line	ENDOMETRIUM	NP_000034	c.870G>A	p.A290A	CCLE	NP	NP
90	HEC59	Cell Line	ENDOMETRIUM	NP_000034	c.397_397delT	p.F133fs	CCLE	NP	NP
91	JHUEM7	Cell Line	ENDOMETRIUM	NP_000034	c.748C>T	p.R250*	CCLE	NP	NP
92	KYO1	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_000034	c.38C>T	p.T13M	CCLE	PASSENGER/OTHER	Probably Damaging
93	KYSE150	Cell Line	OESOPHAGUS	NP_000034	c.836G>A	p.R279H	CCLE	PASSENGER/OTHER	Probably Damaging
94	L1236	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_000034	c.651_splice	p.P217_splice	CCLE	NP	NP
95	LS411N	Cell Line	LARGE INTESTINE	NP_000034	c.711T>C	p.A237A	CCLE	NP	NP
96	NCIH1573	Cell Line	LUNG	NP_000034	c.495C>T	p.C165C	CCLE	NP	NP
97	NCIH1755	Cell Line	LUNG	NP_000034	c.880T>C	p.L294L	CCLE	NP	NP
98	NCIH1838	Cell Line	LUNG	NP_000034	c.799G>T	p.V267F	CCLE	PASSENGER/OTHER	Benign
99	OCILY10	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_000034	c.526T>G	p.W176G	CCLE	PASSENGER/OTHER	Probably Damaging
100	P3HR1	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_000034	c.818A>G	p.Q273R	CCLE	CANCER	Probably Damaging
101	SNU407	Cell Line	LARGE INTESTINE	NP_000034	c.176G>A	p.C59Y	CCLE	CANCER	Probably Damaging
102	SNU81	Cell Line	LARGE INTESTINE	NP_000034	c.568_splice	p.V190_splice	CCLE	NP	NP
103	SUDHL8	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_000034	c.680_684delTTGAC	p.V227fs	CCLE	NP	NP
104	06-25470	Tumour	HAEMATOPOIETIC AND LYMPHOID TISSUE	NM_000043.3	c.696T>G	p.Y232*	COSMIC	NP	NP
105	105307	Tumour	BREAST	NM_000043.3	c.381C>T	p.C127C	COSMIC	NP	NP
106	BB49-HNC	Cell Line	UPPER AERODIGESTIVE TRACT	NM_000043.3	c.805G>A	p.D269N	COSMIC	NP	NP
107	DLBCL-PatientM	Tumour	HAEMATOPOIETIC AND LYMPHOID TISSUE	NM_000043.3	c.733G>C	p.V245L	COSMIC	NP	NP
108	DLBCL-PatientM	Tumour	HAEMATOPOIETIC AND LYMPHOID TISSUE	NM_000043.3	c.794A>G	p.D265G	COSMIC	NP	NP
109	FL-PatientA	Tumour	HAEMATOPOIETIC AND LYMPHOID TISSUE	NM_000043.3	c.826C>T	p.Q276*	COSMIC	NP	NP
110	HCC137T	Tumour	LIVER	NM_000043.3	c.165T>C	p.D55D	COSMIC	NP	NP
111	HCC20T	Tumour	LIVER	NM_000043.3	c.657A>G	p.T219T	COSMIC	NP	NP
112	HCC73T	Tumour	LIVER	NM_000043.3	c.249G>C	p.V83V	COSMIC	NP	NP
113	HN	Tumour	62374 UPPER AERODIGESTIVE TRACT	NM_000043.3	c.631G>T	p.E211*	COSMIC	NP	NP
114	LUAD-5V8LT	Tumour	LUNG	NM_000043.3	c.493T>A	p.C165S	COSMIC	NP	NP
115	LUAD-NYU1021	Tumour	LUNG	NM_000043.3	c.870G>A	p.A290A	COSMIC	NP	NP
116	TCGA-18-3409-01	Tumour	LUNG	NM_000043.3	c.59C>T	p.S20F	COSMIC	NP	NP
117	TCGA-22-5472-01	Tumour	LUNG	NM_000043.3	c.474A>T	p.T158T	COSMIC	NP	NP
118	TCGA-44-6145-01	Tumour	LUNG	NM_000043.3	c.341A>T	p.E114V	COSMIC	NP	NP
119	TCGA-50-5930-01	Tumour	LUNG	NM_000043.3	c.428G>T	p.C143F	COSMIC	NP	NP
120	TCGA-95-7944-01	Tumour	LUNG	NM_000043.3	c.781G>A	p.E261K	COSMIC	NP	NP
121	TCGA-A6-6780-01	Tumour	LARGE INTESTINE	NM_000043.3	c.397delT	p.C135fs*52	COSMIC	NP	NP
122	TCGA-AD-6889-01	Tumour	LARGE INTESTINE	NM_000043.3	c.894_895insA	p.A301fs*20	COSMIC	NP	NP
123	TCGA-AG-3598-01	Tumour	LARGE INTESTINE	NM_000043.3	c.536T>A	p.L179H	COSMIC	NP	NP
124	TCGA-AG-3892-01	Tumour	LARGE INTESTINE	NM_000043.3	c.312T>C	p.C104C	COSMIC	NP	NP
125	TCGA-AG-3892-01	Tumour	LARGE INTESTINE	NM_000043.3	c.925A>C	p.K309Q	COSMIC	NP	NP
126	TCGA-AP-A051-01	Tumour	ENDOMETRIUM	NM_000043.3	c.653A>G	p.E218G	COSMIC	NP	NP
127	TCGA-AP-A051-01	Tumour	ENDOMETRIUM	NM_000043.3	c.869C>T	p.A290V	COSMIC	NP	NP
128	TCGA-AP-A056-01	Tumour	ENDOMETRIUM	NM_000043.3	c.444-1G>T	p.?	COSMIC	NP	NP
129	TCGA-AP-A059-01	Tumour	ENDOMETRIUM	NM_000043.3	c.286C>T	p.H96Y	COSMIC	NP	NP
130	TCGA-AP-A0LM-01	Tumour	ENDOMETRIUM	NM_000043.3	c.608G>T	p.R203I	COSMIC	NP	NP
131	TCGA-AX-A05Z-01	Tumour	ENDOMETRIUM	NM_000043.3	c.189T>C	p.C63C	COSMIC	NP	NP
132	TCGA-AX-A0J1-01	Tumour	ENDOMETRIUM	NM_000043.3	c.870G>A	p.A290A	COSMIC	NP	NP
133	TCGA-AZ-4315-01	Tumour	LARGE INTESTINE	NM_000043.3	c.362G>A	p.R121Q	COSMIC	NP	NP
134	TCGA-B0-5713-01	Tumour	KIDNEY	NM_000043.3	c.835C>A	p.R279S	COSMIC	NP	NP
135	TCGA-B5-A0JY-01	Tumour	ENDOMETRIUM	NM_000043.3	c.801C>A	p.V267V	COSMIC	NP	NP
136	TCGA-B5-A11E-01	Tumour	ENDOMETRIUM	NM_000043.3	c.370A>C	p.N124H	COSMIC	NP	NP
137	TCGA-B8-4154-01	Tumour	KIDNEY	NM_000043.3	c.434C>A	p.P145H	COSMIC	NP	NP
138	TCGA-BS-A0TC-01	Tumour	ENDOMETRIUM	NM_000043.3	c.559A>C	p.I187L	COSMIC	NP	NP
139	TCGA-C8-A12T-01	Tumour	BREAST	NM_000043.3	c.682G>A	p.D228N	COSMIC	NP	NP
140	TCGA-CA-6717-01	Tumour	LARGE INTESTINE	NM_000043.3	c.340G>A	p.E114K	COSMIC	NP	NP
141	TCGA-CK-4947-01	Tumour	LARGE INTESTINE	NM_000043.3	c.542T>C	p.L181P	COSMIC	NP	NP
142	TCGA-CM-5862-01	Tumour	LARGE INTESTINE	NM_000043.3	c.806A>G	p.D269G	COSMIC	NP	NP
143	TCGA-CW-5581-01	Tumour	KIDNEY	NM_000043.3	c.119C>T	p.T40I	COSMIC	NP	NP
144	TCGA-D1-A103-01	Tumour	ENDOMETRIUM	NM_000043.3	c.20T>C	p.L7P	COSMIC	NP	NP
145	TCGA-D1-A16J-01	Tumour	ENDOMETRIUM	NM_000043.3	c.503delA	p.G169fs*18	COSMIC	NP	NP
146	TCGA-D5-6927-01	Tumour	LARGE INTESTINE	NM_000043.3	c.396_397insT	p.C135fs*2	COSMIC	NP	NP
147	YUAVEY	Tumour	SKIN	NM_000043.3	c.739G>A	p.G247S	COSMIC	NP	NP
148	tumor	Tumour	4163639 HAEMATOPOIETIC AND LYMPHOID TISSUE	NM_000043.3	c.656_658CAG>C	p.V220fs*6	COSMIC	NP	NP
149	tumor	Tumour	4163639 HAEMATOPOIETIC AND LYMPHOID TISSUE	NM_000043.3	c.802C>G	p.Q268E	COSMIC	NP	NP
150	BB49HNC	Cell Line	UPPER_AERODIGESTIVE_TRACT	NM_000043.3	c.805G>A	p.D269N	COSMIC	CANCER	POSSIBLY DAMAGING
151	EB2	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	NM_000043.3	c.948G>A	p.K316K	COSMIC	NP	NP
152	GCT	Cell Line	SOFT_TISSUE	NM_000043.3	c.305G>A	p.R102K	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
153	H290	Cell Line	PLEURA	NM_000043.3	c.360C>T	p.T120T	COSMIC	NP	NP
154	JIYOYEP2003	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	NM_000043.3	c.818A>G	p.Q273R	COSMIC	CANCER	PROBABLY DAMAGING
155	KARPAS422	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	NM_000043.3	c.526T>G	p.W176G	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
156	KARPAS45	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	NM_000043.3	c.401T>C	p.F134S	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
157	KYSE150	Cell Line	OESOPHAGUS	NM_000043.3	c.836G>A	p.R279H	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
158	L1236	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	NM_000043.3	c.651+2T>C	p.?	COSMIC	NP	NP
159	LS411N	Cell Line	LARGE_INTESTINE	NM_000043.3	c.711T>C	p.A237A	COSMIC	NP	NP
160	MCC13	Cell Line	SKIN	NM_000043.3	c.293C>T	p.S98F	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
161	MRKNU1	Cell Line	BREAST	NM_000043.3	c.506-3C>T	p.?	COSMIC	NP	NP
162	NCIH1573	Cell Line	LUNG	NM_000043.3	c.495C>T	p.C165C	COSMIC	NP	NP
163	NCIH1755	Cell Line	LUNG	NM_000043.3	c.366C>T	p.T122T	COSMIC	NP	NP
164	NCIH1755	Cell Line	LUNG	NM_000043.3	c.880T>C	p.L294L	COSMIC	NP	NP
165	NCIH1770	Cell Line	LUNG	NM_000043.3	c.197-10C>T	p.?	COSMIC	NP	NP
166	NCIH1838	Cell Line	LUNG	NM_000043.3	c.799G>T	p.V267F	COSMIC	PASSENGER/OTHER	BENIGN
167	PL18	Cell Line	PANCREAS	NM_000043.3	c.937A>G	p.I313V	COSMIC	PASSENGER/OTHER	BENIGN
168	RAJI	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	NM_000043.3	c.575G>T	p.R192I	COSMIC	PASSENGER/OTHER	BENIGN
169	SNU407	Cell Line	LARGE_INTESTINE	NM_000043.3	c.176G>A	p.C59Y	COSMIC	CANCER	PROBABLY DAMAGING
170	SUDHL8	Cell Line	NS	NM_000043.3	c.57G>A	p.S19S	COSMIC	NP	NP
171	SUDHL8	Cell Line	NS	NM_000043.3	c.680_684delTTGAC	p.D228fs*2	COSMIC	NP	NP
172	SW48	Cell Line	LARGE_INTESTINE	NM_000043.3	c.315A>T	p.R105S	COSMIC	PASSENGER/OTHER	BENIGN

*NP: Not Predicted

Domain ID	Domain Name	Start Site	End Site	E-value
PF00020	TNFR_c6	85	127	1.6e-09
PF00020	TNFR_c6	129	165	9.5e-06
PF00531	Death	238	313	1.9e-17
PF12389	Peptidase_M73	256	312	0.11
PF00020	TNFR_c6	85	127	1.6e-09
PF00020	TNFR_c6	129	165	9.5e-06
PF00531	Death	238	313	1.9e-17
PF12389	Peptidase_M73	256	312	0.11

Domain ID	Start Site	End Site	E-value
0036368	218	334	2.45e-37
0043591	48	101	1.06e-09
0039629	106	150	9.03e-10
0036368	218	334	2.45e-37
0043591	48	101	1.06e-09
0039629	106	150	9.03e-10

Proteomics DB	COSMIC	Gene Atlas	STRING	PIR
FAS	FAS	FAS	ENSP00000347426	P25445
QuickGO	HGNC	Ensembl Genome Browser	TreeFam	UniProt
P25445	FAS	ENSP00000347426	FAS	P25445
Expression Atlas	Protein Atlas	OMIM	IntAct	PharmGKB
FAS	ENSP00000347426	134637	P25445	PA165548681

Protein: FAS

Mutation Data (+)

Copy number variation and expression profile (+)

Gene Essentiality Data (+)

Tertiary structure (+)

Structure Domains (+)

Sequence Alignment (+)

Sequence Profiles (+)

Post Translational Modifications (+)

Other Databases Link (+)

Modelled Structure	Structures available in PDB
	1BZI, 1DDF, 3EWT, 3EZQ, 3THM, 3TJE