ApoCanD

#	Name/ID	Cell Line/Tumor sample	Tissue of Origin	Reference ID	cDNA change	Protein change	Source	FATHMM Prediction	PolyPhen2 Prediction
1	BT483	Cell Line	BREAST	NP_061820	c.186G>C	p.E62D	CCLE	PASSENGER/OTHER	Benign
2	HCC1569	Cell Line	BREAST	NP_061820	c.277G>A	p.A93T	CCLE	PASSENGER/OTHER	Benign
3	NCIH2106	Cell Line	LUNG	NP_061820	c.161A>T	p.K54M	CCLE	PASSENGER/OTHER	Benign
4	SNUC2A	Cell Line	LARGE INTESTINE	NP_061820	c.11T>C	p.V4A	CCLE	PASSENGER/OTHER	Benign
5	VMRCLCP	Cell Line	LUNG	NP_061820	c.267G>T	p.K89N	CCLE	PASSENGER/OTHER	Benign
6	ESO-143	Tumour	OESOPHAGUS	ENST00000305786	c.176T>C	p.I59T	COSMIC	NP	NP
7	H322T	Cell Line	LUNG	ENST00000305786	c.226A>G	p.I76V	COSMIC	NP	NP
8	HN	Tumour	62854 UPPER AERODIGESTIVE TRACT	ENST00000305786	c.244A>G	p.I82V	COSMIC	NP	NP
9	NCI-H1770	Cell Line	LUNG	ENST00000305786	c.161A>T	p.K54M	COSMIC	NP	NP
10	TCGA-24-1422-01	Tumour	OVARY	ENST00000305786	c.261G>A	p.K87K	COSMIC	NP	NP
11	TCGA-78-7145-01	Tumour	LUNG	ENST00000305786	c.4G>C	p.G2R	COSMIC	NP	NP
12	TCGA-BG-A0M8-01	Tumour	ENDOMETRIUM	ENST00000305786	c.95A>G	p.N32S	COSMIC	NP	NP
13	TCGA-BS-A0TC-01	Tumour	ENDOMETRIUM	ENST00000305786	c.281A>C	p.D94A	COSMIC	NP	NP
14	TCGA-BS-A0UF-01	Tumour	ENDOMETRIUM	ENST00000305786	c.29T>G	p.I10S	COSMIC	NP	NP
15	TCGA-DM-A1D6-01	Tumour	LARGE INTESTINE	ENST00000305786	c.161A>G	p.K54R	COSMIC	NP	NP
16	BT483	Cell Line	BREAST	ENST00000305786	c.186G>C	p.E62D	COSMIC	PASSENGER/OTHER	BENIGN
17	CAS1	Cell Line	CENTRAL_NERVOUS_SYSTEM	ENST00000305786	c.169+2_169+3insT	p.?	COSMIC	NP	NP
18	NCIH1770	Cell Line	LUNG	ENST00000305786	c.161A>T	p.K54M	COSMIC	PASSENGER/OTHER	BENIGN
19	NCIH322M	Cell Line	LUNG	ENST00000305786	c.226A>G	p.I76V	COSMIC	PASSENGER/OTHER	BENIGN
20	NCIH322M	Cell Line	LUNG	ENST00000305786	c.313G>T	p.E105*	COSMIC	NP	NP
21	SKMEL3	Cell Line	SKIN	ENST00000305786	c.147C>T	p.Y49Y	COSMIC	NP	NP
22	SNUC2B	Cell Line	LARGE_INTESTINE	ENST00000305786	c.11T>C	p.V4A	COSMIC	PASSENGER/OTHER	BENIGN
23	SW1417	Cell Line	LARGE_INTESTINE	ENST00000305786	c.147C>T	p.Y49Y	COSMIC	NP	NP
24	BT483	Cell Line	BREAST	NP_061820	c.186G>C	p.E62D	CCLE	PASSENGER/OTHER	Benign
25	HCC1569	Cell Line	BREAST	NP_061820	c.277G>A	p.A93T	CCLE	PASSENGER/OTHER	Benign
26	NCIH2106	Cell Line	LUNG	NP_061820	c.161A>T	p.K54M	CCLE	PASSENGER/OTHER	Benign
27	SNUC2A	Cell Line	LARGE INTESTINE	NP_061820	c.11T>C	p.V4A	CCLE	PASSENGER/OTHER	Benign
28	VMRCLCP	Cell Line	LUNG	NP_061820	c.267G>T	p.K89N	CCLE	PASSENGER/OTHER	Benign
29	ESO-143	Tumour	OESOPHAGUS	ENST00000305786	c.176T>C	p.I59T	COSMIC	NP	NP
30	H322T	Cell Line	LUNG	ENST00000305786	c.226A>G	p.I76V	COSMIC	NP	NP
31	HN	Tumour	62854 UPPER AERODIGESTIVE TRACT	ENST00000305786	c.244A>G	p.I82V	COSMIC	NP	NP
32	NCI-H1770	Cell Line	LUNG	ENST00000305786	c.161A>T	p.K54M	COSMIC	NP	NP
33	TCGA-24-1422-01	Tumour	OVARY	ENST00000305786	c.261G>A	p.K87K	COSMIC	NP	NP
34	TCGA-78-7145-01	Tumour	LUNG	ENST00000305786	c.4G>C	p.G2R	COSMIC	NP	NP
35	TCGA-BG-A0M8-01	Tumour	ENDOMETRIUM	ENST00000305786	c.95A>G	p.N32S	COSMIC	NP	NP
36	TCGA-BS-A0TC-01	Tumour	ENDOMETRIUM	ENST00000305786	c.281A>C	p.D94A	COSMIC	NP	NP
37	TCGA-BS-A0UF-01	Tumour	ENDOMETRIUM	ENST00000305786	c.29T>G	p.I10S	COSMIC	NP	NP
38	TCGA-DM-A1D6-01	Tumour	LARGE INTESTINE	ENST00000305786	c.161A>G	p.K54R	COSMIC	NP	NP
39	BT483	Cell Line	BREAST	ENST00000305786	c.186G>C	p.E62D	COSMIC	PASSENGER/OTHER	BENIGN
40	CAS1	Cell Line	CENTRAL_NERVOUS_SYSTEM	ENST00000305786	c.169+2_169+3insT	p.?	COSMIC	NP	NP
41	NCIH1770	Cell Line	LUNG	ENST00000305786	c.161A>T	p.K54M	COSMIC	PASSENGER/OTHER	BENIGN
42	NCIH322M	Cell Line	LUNG	ENST00000305786	c.226A>G	p.I76V	COSMIC	PASSENGER/OTHER	BENIGN
43	NCIH322M	Cell Line	LUNG	ENST00000305786	c.313G>T	p.E105*	COSMIC	NP	NP
44	SKMEL3	Cell Line	SKIN	ENST00000305786	c.147C>T	p.Y49Y	COSMIC	NP	NP
45	SNUC2B	Cell Line	LARGE_INTESTINE	ENST00000305786	c.11T>C	p.V4A	COSMIC	PASSENGER/OTHER	BENIGN
46	SW1417	Cell Line	LARGE_INTESTINE	ENST00000305786	c.147C>T	p.Y49Y	COSMIC	NP	NP

*NP: Not Predicted

Proteomics DB	COSMIC	Gene Atlas	STRING	PIR
CYCS	CYCS	CYCS	ENSP00000307786	P99999
QuickGO	HGNC	Ensembl Genome Browser	TreeFam	UniProt
P99999	CYCS	ENSP00000307786	CYCS	P99999
Expression Atlas	Protein Atlas	OMIM	IntAct	PharmGKB
CYCS	ENSP00000307786	123970	P99999	PA134981636

Protein: CYCS

Mutation Data (+)

Copy number variation and expression profile (+)

Gene Essentiality Data (+)

Tertiary structure (+)

Structure Domains (+)

Sequence Alignment (+)

Sequence Profiles (+)

Post Translational Modifications (+)

Other Databases Link (+)

Modelled Structure	Structures available in PDB
	1J3S, 3NWV, 3ZCF, 3ZOO