ApoCanD

#	Name/ID	Cell Line/Tumor sample	Tissue of Origin	Reference ID	cDNA change	Protein change	Source	FATHMM Prediction	PolyPhen2 Prediction
1	AN3CA	Cell Line	ENDOMETRIUM	NP_001220	c.440G>A	p.G147E	CCLE	PASSENGER/OTHER	Benign
2	HEC108	Cell Line	ENDOMETRIUM	NP_001220	c.1222C>T	p.R408W	CCLE	PASSENGER/OTHER	Probably Damaging
3	HEC251	Cell Line	ENDOMETRIUM	NP_001220	c.1024T>G	p.F342V	CCLE	PASSENGER/OTHER	Benign
4	HEL	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_001220	c.1205G>C	p.G402A	CCLE	PASSENGER/OTHER	Probably Damaging
5	HEL9217	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_001220	c.1205G>C	p.G402A	CCLE	PASSENGER/OTHER	Probably Damaging
6	HS766T	Cell Line	PANCREAS	NP_001220	c.427_427delG	p.E143fs	CCLE	NP	NP
7	MEWO	Cell Line	SKIN	NP_001220	c.1048_splice	p.G350_splice	CCLE	NP	NP
8	MFE319	Cell Line	ENDOMETRIUM	NP_001220	c.283G>A	p.A95T	CCLE	PASSENGER/OTHER	Benign
9	NCIH1915	Cell Line	LUNG	NP_001220	c.135G>C	p.R45R	CCLE	NP	NP
10	NCIH650	Cell Line	LUNG	NP_001220	c.929G>T	p.S310I	CCLE	PASSENGER/OTHER	Benign
11	OC316	Cell Line	OVARY	NP_001220	c.260C>T	p.S87L	CCLE	PASSENGER/OTHER	Probably Damaging
12	SNU1040	Cell Line	LARGE INTESTINE	NP_001220	c.1161C>T	p.V387V	CCLE	NP	NP
13	SNU886	Cell Line	LIVER	NP_001220	c.247G>T	p.D83Y	CCLE	PASSENGER/OTHER	Benign
14	WM793	Cell Line	SKIN	NP_001220	c.988G>A	p.D330N	CCLE	PASSENGER/OTHER	Probably Damaging
15	ESO-408	Tumour	OESOPHAGUS	ENST00000333868	c.418G>A	p.G140S	COSMIC	NP	NP
16	GC8	Tumour	T STOMACH	ENST00000333868	c.408T>C	p.F136F	COSMIC	NP	NP
17	HCC2998	Cell Line	LARGE INTESTINE	ENST00000333868	c.1236C>A	p.F412L	COSMIC	NP	NP
18	LB1047-RCC	Cell Line	KIDNEY	ENST00000333868	c.884G>T	p.G295V	COSMIC	NP	NP
19	LC	Tumour	C8 LUNG	ENST00000333868	c.874A>G	p.K292E	COSMIC	NP	NP
20	LUAD-B02216	Tumour	LUNG	ENST00000333868	c.1037C>A	p.S346Y	COSMIC	NP	NP
21	MD-306	Tumour	CENTRAL NERVOUS SYSTEM	ENST00000333868	c.691G>A	p.V231M	COSMIC	NP	NP
22	P00-000450	Tumour	PROSTATE	ENST00000333868	c.260C>T	p.S87L	COSMIC	NP	NP
23	TCGA-02-0083-01	Tumour	CENTRAL NERVOUS SYSTEM	ENST00000333868	c.401G>A	p.G134E	COSMIC	NP	NP
24	TCGA-18-3406-01	Tumour	LUNG	ENST00000333868	c.135G>T	p.R45R	COSMIC	NP	NP
25	TCGA-23-1120-01	Tumour	OVARY	ENST00000333868	c.734A>C	p.Q245P	COSMIC	NP	NP
26	TCGA-33-4532-01	Tumour	LUNG	ENST00000333868	c.1009A>G	p.T337A	COSMIC	NP	NP
27	TCGA-38-4632-01	Tumour	LUNG	ENST00000333868	c.173T>G	p.L58R	COSMIC	NP	NP
28	TCGA-42-2591-01	Tumour	OVARY	ENST00000333868	c.990C>A	p.D330E	COSMIC	NP	NP
29	TCGA-49-4486-01	Tumour	LUNG	ENST00000333868	c.1179G>A	p.V393V	COSMIC	NP	NP
30	TCGA-50-5068-01	Tumour	LUNG	ENST00000333868	c.447A>T	p.A149A	COSMIC	NP	NP
31	TCGA-63-6202-01	Tumour	LUNG	ENST00000333868	c.492C>T	p.L164L	COSMIC	NP	NP
32	TCGA-66-2754-01	Tumour	LUNG	ENST00000333868	c.194G>T	p.R65L	COSMIC	NP	NP
33	TCGA-66-2785-01	Tumour	LUNG	ENST00000333868	c.194G>C	p.R65P	COSMIC	NP	NP
34	TCGA-95-7043-01	Tumour	LUNG	ENST00000333868	c.401G>T	p.G134V	COSMIC	NP	NP
35	TCGA-A6-6781-01	Tumour	LARGE INTESTINE	ENST00000333868	c.532C>T	p.R178C	COSMIC	NP	NP
36	TCGA-AA-3496-01	Tumour	LARGE INTESTINE	ENST00000333868	c.323C>A	p.P108Q	COSMIC	NP	NP
37	TCGA-AA-3542-01	Tumour	LARGE INTESTINE	ENST00000333868	c.1120T>A	p.W374R	COSMIC	NP	NP
38	TCGA-AA-3877-01	Tumour	LARGE INTESTINE	ENST00000333868	c.578G>A	p.R193H	COSMIC	NP	NP
39	TCGA-AP-A051-01	Tumour	ENDOMETRIUM	ENST00000333868	c.539G>A	p.R180H	COSMIC	NP	NP
40	TCGA-AP-A054-01	Tumour	ENDOMETRIUM	ENST00000333868	c.804T>C	p.N268N	COSMIC	NP	NP
41	TCGA-AP-A059-01	Tumour	ENDOMETRIUM	ENST00000333868	c.1027G>A	p.V343M	COSMIC	NP	NP
42	TCGA-AP-A059-01	Tumour	ENDOMETRIUM	ENST00000333868	c.1209C>T	p.C403C	COSMIC	NP	NP
43	TCGA-AZ-6601-01	Tumour	LARGE INTESTINE	ENST00000333868	c.402A>G	p.G134G	COSMIC	NP	NP
44	TCGA-B5-A0JY-01	Tumour	ENDOMETRIUM	ENST00000333868	c.242G>A	p.G81D	COSMIC	NP	NP
45	TCGA-CI-6620-01	Tumour	LARGE INTESTINE	ENST00000333868	c.400G>A	p.G134R	COSMIC	NP	NP
46	TCGA-CM-6161-01	Tumour	LARGE INTESTINE	ENST00000333868	c.402A>G	p.G134G	COSMIC	NP	NP
47	TCGA-CM-6170-01	Tumour	LARGE INTESTINE	ENST00000333868	c.337C>T	p.P113S	COSMIC	NP	NP
48	TCGA-D8-A1Y1-01	Tumour	BREAST	ENST00000333868	c.777G>A	p.S259S	COSMIC	NP	NP
49	TCGA-DI-A0WH-01	Tumour	ENDOMETRIUM	ENST00000333868	c.465G>T	p.L155L	COSMIC	NP	NP
50	TCGA-G2-A2EF-01	Tumour	URINARY TRACT	ENST00000333868	c.869-1G>C	p.?	COSMIC	NP	NP
51	YUAKER	Tumour	SKIN	ENST00000333868	c.373A>C	p.T125P	COSMIC	NP	NP
52	YURTHE	Tumour	SKIN	ENST00000333868	c.670C>T	p.H224Y	COSMIC	NP	NP
53	YUTEPA	Tumour	SKIN	ENST00000333868	c.1027G>A	p.V343M	COSMIC	NP	NP
54	YUWHIM	Tumour	SKIN	ENST00000333868	c.548C>T	p.S183F	COSMIC	NP	NP
55	AN3CA	Cell Line	ENDOMETRIUM	ENST00000333868	c.440G>A	p.G147E	COSMIC	PASSENGER/OTHER	BENIGN
56	EN	Cell Line	ENDOMETRIUM	ENST00000333868	c.251T>C	p.M84T	COSMIC	PASSENGER/OTHER	BENIGN
57	GOTO	Cell Line	AUTONOMIC_GANGLIA	ENST00000333868	c.1197G>T	p.Q399H	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
58	HCC1937	Cell Line	BREAST	ENST00000333868	c.916G>A	p.E306K	COSMIC	PASSENGER/OTHER	BENIGN
59	HCC2998	Cell Line	LARGE_INTESTINE	ENST00000333868	c.1236C>A	p.F412L	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
60	HEL	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000333868	c.1205G>C	p.G402A	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
61	HEMCSS	Cell Line	BONE	ENST00000333868	c.193C>G	p.R65G	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
62	HS766T	Cell Line	PANCREAS	ENST00000333868	c.427delG	p.E143fs*3	COSMIC	NP	NP
63	MFE319	Cell Line	ENDOMETRIUM	ENST00000333868	c.283G>A	p.A95T	COSMIC	PASSENGER/OTHER	BENIGN
64	MHHPREB1	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000333868	c.269G>A	p.R90Q	COSMIC	PASSENGER/OTHER	BENIGN
65	NCIH1915	Cell Line	LUNG	ENST00000333868	c.135G>C	p.R45R	COSMIC	NP	NP
66	OC314	Cell Line	OVARY	ENST00000333868	c.260C>T	p.S87L	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
67	SARC9371	Cell Line	BONE	ENST00000333868	c.365G>A	p.R122K	COSMIC	PASSENGER/OTHER	BENIGN
68	SNU1040	Cell Line	LARGE_INTESTINE	ENST00000333868	c.1161C>T	p.V387V	COSMIC	NP	NP
69	SNU1040	Cell Line	LARGE_INTESTINE	ENST00000333868	c.835C>A	p.P279T	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
70	SW684	Cell Line	SOFT_TISSUE	ENST00000333868	c.1247C>T	p.S416L	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
71	VMRCMELG	Cell Line	SKIN	ENST00000333868	c.1159-3C>A	p.?	COSMIC	NP	NP
72	WM793B	Cell Line	SKIN	ENST00000333868	c.988G>A	p.D330N	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
73	AN3CA	Cell Line	ENDOMETRIUM	NP_001220	c.440G>A	p.G147E	CCLE	PASSENGER/OTHER	Benign
74	HEC108	Cell Line	ENDOMETRIUM	NP_001220	c.1222C>T	p.R408W	CCLE	PASSENGER/OTHER	Probably Damaging
75	HEC251	Cell Line	ENDOMETRIUM	NP_001220	c.1024T>G	p.F342V	CCLE	PASSENGER/OTHER	Benign
76	HEL	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_001220	c.1205G>C	p.G402A	CCLE	PASSENGER/OTHER	Probably Damaging
77	HEL9217	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_001220	c.1205G>C	p.G402A	CCLE	PASSENGER/OTHER	Probably Damaging
78	HS766T	Cell Line	PANCREAS	NP_001220	c.427_427delG	p.E143fs	CCLE	NP	NP
79	MEWO	Cell Line	SKIN	NP_001220	c.1048_splice	p.G350_splice	CCLE	NP	NP
80	MFE319	Cell Line	ENDOMETRIUM	NP_001220	c.283G>A	p.A95T	CCLE	PASSENGER/OTHER	Benign
81	NCIH1915	Cell Line	LUNG	NP_001220	c.135G>C	p.R45R	CCLE	NP	NP
82	NCIH650	Cell Line	LUNG	NP_001220	c.929G>T	p.S310I	CCLE	PASSENGER/OTHER	Benign
83	OC316	Cell Line	OVARY	NP_001220	c.260C>T	p.S87L	CCLE	PASSENGER/OTHER	Probably Damaging
84	SNU1040	Cell Line	LARGE INTESTINE	NP_001220	c.1161C>T	p.V387V	CCLE	NP	NP
85	SNU886	Cell Line	LIVER	NP_001220	c.247G>T	p.D83Y	CCLE	PASSENGER/OTHER	Benign
86	WM793	Cell Line	SKIN	NP_001220	c.988G>A	p.D330N	CCLE	PASSENGER/OTHER	Probably Damaging
87	ESO-408	Tumour	OESOPHAGUS	ENST00000333868	c.418G>A	p.G140S	COSMIC	NP	NP
88	GC8	Tumour	T STOMACH	ENST00000333868	c.408T>C	p.F136F	COSMIC	NP	NP
89	HCC2998	Cell Line	LARGE INTESTINE	ENST00000333868	c.1236C>A	p.F412L	COSMIC	NP	NP
90	LB1047-RCC	Cell Line	KIDNEY	ENST00000333868	c.884G>T	p.G295V	COSMIC	NP	NP
91	LC	Tumour	C8 LUNG	ENST00000333868	c.874A>G	p.K292E	COSMIC	NP	NP
92	LUAD-B02216	Tumour	LUNG	ENST00000333868	c.1037C>A	p.S346Y	COSMIC	NP	NP
93	MD-306	Tumour	CENTRAL NERVOUS SYSTEM	ENST00000333868	c.691G>A	p.V231M	COSMIC	NP	NP
94	P00-000450	Tumour	PROSTATE	ENST00000333868	c.260C>T	p.S87L	COSMIC	NP	NP
95	TCGA-02-0083-01	Tumour	CENTRAL NERVOUS SYSTEM	ENST00000333868	c.401G>A	p.G134E	COSMIC	NP	NP
96	TCGA-18-3406-01	Tumour	LUNG	ENST00000333868	c.135G>T	p.R45R	COSMIC	NP	NP
97	TCGA-23-1120-01	Tumour	OVARY	ENST00000333868	c.734A>C	p.Q245P	COSMIC	NP	NP
98	TCGA-33-4532-01	Tumour	LUNG	ENST00000333868	c.1009A>G	p.T337A	COSMIC	NP	NP
99	TCGA-38-4632-01	Tumour	LUNG	ENST00000333868	c.173T>G	p.L58R	COSMIC	NP	NP
100	TCGA-42-2591-01	Tumour	OVARY	ENST00000333868	c.990C>A	p.D330E	COSMIC	NP	NP
101	TCGA-49-4486-01	Tumour	LUNG	ENST00000333868	c.1179G>A	p.V393V	COSMIC	NP	NP
102	TCGA-50-5068-01	Tumour	LUNG	ENST00000333868	c.447A>T	p.A149A	COSMIC	NP	NP
103	TCGA-63-6202-01	Tumour	LUNG	ENST00000333868	c.492C>T	p.L164L	COSMIC	NP	NP
104	TCGA-66-2754-01	Tumour	LUNG	ENST00000333868	c.194G>T	p.R65L	COSMIC	NP	NP
105	TCGA-66-2785-01	Tumour	LUNG	ENST00000333868	c.194G>C	p.R65P	COSMIC	NP	NP
106	TCGA-95-7043-01	Tumour	LUNG	ENST00000333868	c.401G>T	p.G134V	COSMIC	NP	NP
107	TCGA-A6-6781-01	Tumour	LARGE INTESTINE	ENST00000333868	c.532C>T	p.R178C	COSMIC	NP	NP
108	TCGA-AA-3496-01	Tumour	LARGE INTESTINE	ENST00000333868	c.323C>A	p.P108Q	COSMIC	NP	NP
109	TCGA-AA-3542-01	Tumour	LARGE INTESTINE	ENST00000333868	c.1120T>A	p.W374R	COSMIC	NP	NP
110	TCGA-AA-3877-01	Tumour	LARGE INTESTINE	ENST00000333868	c.578G>A	p.R193H	COSMIC	NP	NP
111	TCGA-AP-A051-01	Tumour	ENDOMETRIUM	ENST00000333868	c.539G>A	p.R180H	COSMIC	NP	NP
112	TCGA-AP-A054-01	Tumour	ENDOMETRIUM	ENST00000333868	c.804T>C	p.N268N	COSMIC	NP	NP
113	TCGA-AP-A059-01	Tumour	ENDOMETRIUM	ENST00000333868	c.1027G>A	p.V343M	COSMIC	NP	NP
114	TCGA-AP-A059-01	Tumour	ENDOMETRIUM	ENST00000333868	c.1209C>T	p.C403C	COSMIC	NP	NP
115	TCGA-AZ-6601-01	Tumour	LARGE INTESTINE	ENST00000333868	c.402A>G	p.G134G	COSMIC	NP	NP
116	TCGA-B5-A0JY-01	Tumour	ENDOMETRIUM	ENST00000333868	c.242G>A	p.G81D	COSMIC	NP	NP
117	TCGA-CI-6620-01	Tumour	LARGE INTESTINE	ENST00000333868	c.400G>A	p.G134R	COSMIC	NP	NP
118	TCGA-CM-6161-01	Tumour	LARGE INTESTINE	ENST00000333868	c.402A>G	p.G134G	COSMIC	NP	NP
119	TCGA-CM-6170-01	Tumour	LARGE INTESTINE	ENST00000333868	c.337C>T	p.P113S	COSMIC	NP	NP
120	TCGA-D8-A1Y1-01	Tumour	BREAST	ENST00000333868	c.777G>A	p.S259S	COSMIC	NP	NP
121	TCGA-DI-A0WH-01	Tumour	ENDOMETRIUM	ENST00000333868	c.465G>T	p.L155L	COSMIC	NP	NP
122	TCGA-G2-A2EF-01	Tumour	URINARY TRACT	ENST00000333868	c.869-1G>C	p.?	COSMIC	NP	NP
123	YUAKER	Tumour	SKIN	ENST00000333868	c.373A>C	p.T125P	COSMIC	NP	NP
124	YURTHE	Tumour	SKIN	ENST00000333868	c.670C>T	p.H224Y	COSMIC	NP	NP
125	YUTEPA	Tumour	SKIN	ENST00000333868	c.1027G>A	p.V343M	COSMIC	NP	NP
126	YUWHIM	Tumour	SKIN	ENST00000333868	c.548C>T	p.S183F	COSMIC	NP	NP
127	AN3CA	Cell Line	ENDOMETRIUM	ENST00000333868	c.440G>A	p.G147E	COSMIC	PASSENGER/OTHER	BENIGN
128	EN	Cell Line	ENDOMETRIUM	ENST00000333868	c.251T>C	p.M84T	COSMIC	PASSENGER/OTHER	BENIGN
129	GOTO	Cell Line	AUTONOMIC_GANGLIA	ENST00000333868	c.1197G>T	p.Q399H	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
130	HCC1937	Cell Line	BREAST	ENST00000333868	c.916G>A	p.E306K	COSMIC	PASSENGER/OTHER	BENIGN
131	HCC2998	Cell Line	LARGE_INTESTINE	ENST00000333868	c.1236C>A	p.F412L	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
132	HEL	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000333868	c.1205G>C	p.G402A	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
133	HEMCSS	Cell Line	BONE	ENST00000333868	c.193C>G	p.R65G	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
134	HS766T	Cell Line	PANCREAS	ENST00000333868	c.427delG	p.E143fs*3	COSMIC	NP	NP
135	MFE319	Cell Line	ENDOMETRIUM	ENST00000333868	c.283G>A	p.A95T	COSMIC	PASSENGER/OTHER	BENIGN
136	MHHPREB1	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000333868	c.269G>A	p.R90Q	COSMIC	PASSENGER/OTHER	BENIGN
137	NCIH1915	Cell Line	LUNG	ENST00000333868	c.135G>C	p.R45R	COSMIC	NP	NP
138	OC314	Cell Line	OVARY	ENST00000333868	c.260C>T	p.S87L	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
139	SARC9371	Cell Line	BONE	ENST00000333868	c.365G>A	p.R122K	COSMIC	PASSENGER/OTHER	BENIGN
140	SNU1040	Cell Line	LARGE_INTESTINE	ENST00000333868	c.1161C>T	p.V387V	COSMIC	NP	NP
141	SNU1040	Cell Line	LARGE_INTESTINE	ENST00000333868	c.835C>A	p.P279T	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
142	SW684	Cell Line	SOFT_TISSUE	ENST00000333868	c.1247C>T	p.S416L	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
143	VMRCMELG	Cell Line	SKIN	ENST00000333868	c.1159-3C>A	p.?	COSMIC	NP	NP
144	WM793B	Cell Line	SKIN	ENST00000333868	c.988G>A	p.D330N	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING

*NP: Not Predicted

Tissue Type	Mean Expression Value	Median Expression Value	Mean CNV	Median CNV

AUTONOMIC GANGLIA	6.6098	6.482	-0.6844	-0.8843
BILIARY TRACT	7.1429	7.2049	-0.3502	-0.355
BONE	6.9960	7.0507	0.0743	7e-04
BREAST	6.8485	6.7906	-0.1709	-0.1338
CENTRAL NERVOUS SYSTEM	7.2437	7.2673	-0.0501	-0.015
ENDOMETRIUM	7.4006	7.4016	-0.0093	-0.0111
HAEMATOPOIETIC AND LYMPHOID TISSUE	7.6142	7.5511	0.0037	0.0004714
KIDNEY	6.9636	6.9475	-0.3312	-0.2033
LARGE INTESTINE	7.2007	7.1325	-0.1418	-0.05445
LIVER	7.3314	7.1729	-0.0599	-0.07982
LUNG	7.4350	7.35355	-0.0814	-0.07346
OESOPHAGUS	7.0892	7.08695	-0.1594	-0.0561
OVARY	7.4212	7.3351	-0.0243	0.0114
PANCREAS	7.2680	7.2981	-0.1635	-0.1972
PLEURA	6.7719	6.9239	-0.2104	-0.1519
PROSTATE	7.1493	7.10835	-0.1542	-0.0268
SALIVARY GLAND	5.7270	5.727	-0.3822	-0.3822
SKIN	7.1446	7.1456	0.0540	0.0195
SMALL INTESTINE	8.6677	8.6677	0.0328	0.03281
SOFT TISSUE	7.5286	7.4768	0.0592	0.0193
STOMACH	7.4368	7.53325	-0.0702	-0.07935
THYROID	7.1539	7.2215	0.1605	0.20585
UPPER AERODIGESTIVE TRACT	6.9516	7.0243	-0.1224	-0.0066736
URINARY TRACT	7.0367	7.01465	-0.1055	-0.043995

Domain ID	Domain Name	Start Site	End Site	E-value
PF00619	CARD	7	90	1.2e-18
PF00656	Peptidase_C14	162	413	2.2e-45
PF01642	MM_CoA_mutase	356	375	0.37
PF00619	CARD	7	90	1.2e-18
PF00656	Peptidase_C14	162	413	2.2e-45
PF01642	MM_CoA_mutase	356	375	0.37

Domain ID	Start Site	End Site	E-value
0039807	144	414	4.64e-91
0045580	1	92	1.51e-25
0039807	144	414	4.64e-91
0045580	1	92	1.51e-25

S. No.	Position	Amino acid	Type	Description
1	115	I	Proteolytic Cleavage	none
2	125	T	Phosphorylation	Phosphothreonine
3	125	T	Phosphorylation	Phosphothreonine (CDK1;MAPK3;MAPK1)
4	125	T	Phosphorylation	Phosphothreonine; by MAPK1.
5	125	T	Phosphorylation (MAP2K1)	Phosphothreonine
6	125	T	Phosphorylation (MAP2K2)	Phosphothreonine
7	125	T	Phosphorylation (MAPK1)	Phosphothreonine
8	125	T	Phosphorylation (MAPK3)	Phosphothreonine
9	144	S	Phosphorylation	Phosphoserine
10	144	S	Phosphorylation	Phosphoserine (PKC_zeta)
11	144	S	Phosphorylation (PRKCZ)	Phosphoserine
12	153	Y	Phosphorylation	Phosphotyrosine
13	153	Y	Phosphorylation	Phosphotyrosine (Abl)
14	153	Y	Phosphorylation (ABL1)	Phosphotyrosine
15	183	S	Phosphorylation	Phosphoserine
16	183	S	Phosphorylation (AKT1)	Phosphoserine
17	195	S	Phosphorylation	Phosphoserine
18	196	S	Phosphorylation	Phosphoserine
19	196	S	Phosphorylation	Phosphoserine (PKB_group)
20	196	S	Phosphorylation (AKT1)	Phosphoserine
21	302	S	Phosphorylation	Phosphoserine
22	302	S	Phosphorylation	Phosphoserine.
23	307	S	Phosphorylation	Phosphoserine
24	307	S	Phosphorylation	Phosphoserine.
25	310	S	Phosphorylation	Phosphoserine
26	310	S	Phosphorylation	Phosphoserine.
27	315	D	Proteolytic Cleavage	none
28	330	D	Proteolytic Cleavage	none
29	99	S	Phosphorylation	Phosphoserine
30	115	I	Proteolytic Cleavage	none
31	125	T	Phosphorylation	Phosphothreonine
32	125	T	Phosphorylation	Phosphothreonine (CDK1;MAPK3;MAPK1)
33	125	T	Phosphorylation	Phosphothreonine; by MAPK1.
34	125	T	Phosphorylation (MAP2K1)	Phosphothreonine
35	125	T	Phosphorylation (MAP2K2)	Phosphothreonine
36	125	T	Phosphorylation (MAPK1)	Phosphothreonine
37	125	T	Phosphorylation (MAPK3)	Phosphothreonine
38	144	S	Phosphorylation	Phosphoserine
39	144	S	Phosphorylation	Phosphoserine (PKC_zeta)
40	144	S	Phosphorylation (PRKCZ)	Phosphoserine
41	153	Y	Phosphorylation	Phosphotyrosine
42	153	Y	Phosphorylation	Phosphotyrosine (Abl)
43	153	Y	Phosphorylation (ABL1)	Phosphotyrosine
44	183	S	Phosphorylation	Phosphoserine
45	183	S	Phosphorylation (AKT1)	Phosphoserine
46	195	S	Phosphorylation	Phosphoserine
47	196	S	Phosphorylation	Phosphoserine
48	196	S	Phosphorylation	Phosphoserine (PKB_group)
49	196	S	Phosphorylation (AKT1)	Phosphoserine
50	302	S	Phosphorylation	Phosphoserine
51	302	S	Phosphorylation	Phosphoserine.
52	307	S	Phosphorylation	Phosphoserine
53	307	S	Phosphorylation	Phosphoserine.
54	310	S	Phosphorylation	Phosphoserine
55	310	S	Phosphorylation	Phosphoserine.
56	315	D	Proteolytic Cleavage	none
57	330	D	Proteolytic Cleavage	none
58	99	S	Phosphorylation	Phosphoserine

Proteomics DB	COSMIC	Gene Atlas	STRING	PIR
CASP9	CASP9	CASP9	ENSP00000330237	P55211
QuickGO	HGNC	Ensembl Genome Browser	TreeFam	UniProt
P55211	CASP9	ENSP00000330237	CASP9	P55211
Expression Atlas	Protein Atlas	OMIM	IntAct	PharmGKB
CASP9	ENSP00000330237	602234	P55211	PA26094

Protein: CASP9

Mutation Data (+)

Copy number variation and expression profile (+)

Gene Essentiality Data (+)

Tertiary structure (+)

Structure Domains (+)

Sequence Alignment (+)

Sequence Profiles (+)

Post Translational Modifications (+)

Other Databases Link (+)

Modelled Structure	Structures available in PDB
	1JXQ, 1NW9, 2AR9, 3D9T, 3V3K, 3YGS