ApoCanD

#	Name/ID	Cell Line/Tumor sample	Tissue of Origin	Reference ID	cDNA change	Protein change	Source	FATHMM Prediction	PolyPhen2 Prediction
1	HEC108	Cell Line	ENDOMETRIUM	NP_277038	c.410T>A	p.L137H	CCLE	NA	Probably Damaging
2	HEC151	Cell Line	ENDOMETRIUM	NP_277038	c.362_363delCC	p.P121fs	CCLE	NA	NP
3	HPBALL	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_277038	c.421G>A	p.A141T	CCLE	NA	Probably Damaging
4	HT115	Cell Line	LARGE INTESTINE	NP_277038	c.528G>T	p.E176D	CCLE	NA	Probably Damaging
5	JMSU1	Cell Line	URINARY TRACT	NP_277038	c.388G>A	p.E130K	CCLE	NA	Probably Damaging
6	NCIH2170	Cell Line	LUNG	NP_277038	c.417C>A	p.C139*	CCLE	NA	NP
7	REH	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_277038	c.307C>T	p.R103W	CCLE	NA	Probably Damaging
8	SUDHL1	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_277038	c.270G>T	p.E90D	CCLE	NA	Benign
9	585208	Tumour	LUNG	ENST00000354670	c.301G>A	p.G101S	COSMIC	NP	NP
10	587332	Tumour	LARGE INTESTINE	ENST00000354670	c.24G>T	p.E8D	COSMIC	NP	NP
11	CLL040	Tumour	HAEMATOPOIETIC AND LYMPHOID TISSUE	ENST00000354670	c.261G>A	p.G87G	COSMIC	NP	NP
12	HCT-116	Cell Line	LARGE INTESTINE	ENST00000354670	c.65C>T	p.P22L	COSMIC	NP	NP
13	LOXIMVI	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	ENST00000354670	c.3G>A	p.M1I	COSMIC	NP	NP
14	LUAD-S01341	Tumour	LUNG	ENST00000354670	c.453+2T>A	p.?	COSMIC	NP	NP
15	OCC06PT	Tumour	OVARY	ENST00000354670	c.152delC	p.P51fs*38	COSMIC	NP	NP
16	TCGA-A6-3809-01	Tumour	LARGE INTESTINE	ENST00000354670	c.386C>T	p.A129V	COSMIC	NP	NP
17	TCGA-A6-6781-01	Tumour	LARGE INTESTINE	ENST00000354670	c.144G>T	p.Q48H	COSMIC	NP	NP
18	TCGA-AA-3558-01	Tumour	LARGE INTESTINE	ENST00000354670	c.69G>T	p.V23V	COSMIC	NP	NP
19	TCGA-AA-3663-01	Tumour	LARGE INTESTINE	ENST00000354670	c.363delC	p.E122fs*51	COSMIC	NP	NP
20	TCGA-AA-A010-01	Tumour	LARGE INTESTINE	ENST00000354670	c.467A>G	p.Q156R	COSMIC	NP	NP
21	TCGA-AP-A051-01	Tumour	ENDOMETRIUM	ENST00000354670	c.216T>C	p.T72T	COSMIC	NP	NP
22	TCGA-AP-A052-01	Tumour	ENDOMETRIUM	ENST00000354670	c.73C>T	p.Q25*	COSMIC	NP	NP
23	TCGA-B5-A0K6-01	Tumour	ENDOMETRIUM	ENST00000354670	c.14_15delAG	p.Q5fs*8	COSMIC	NP	NP
24	TCGA-D1-A165-01	Tumour	ENDOMETRIUM	ENST00000354670	c.142C>T	p.Q48*	COSMIC	NP	NP
25	TCGA-DK-A1AC-01	Tumour	URINARY TRACT	ENST00000354670	c.412C>T	p.Q138*	COSMIC	NP	NP
26	TCGA-G2-A2EC-01	Tumour	URINARY TRACT	ENST00000354670	c.404G>A	p.R135Q	COSMIC	NP	NP
27	AGS	Cell Line	STOMACH	ENST00000354670	c.293-4G>T	p.?	COSMIC	NP	NP
28	AGS	Cell Line	STOMACH	ENST00000354670	c.7C>A	p.P3T	COSMIC	no weights	POSSIBLY DAMAGING
29	FARAGE	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000354670	c.503A>G	p.H168R	COSMIC	no weights	BENIGN
30	HCT116	Cell Line	LARGE_INTESTINE	ENST00000354670	c.65C>T	p.P22L	COSMIC	no weights	BENIGN
31	HT115	Cell Line	LARGE_INTESTINE	ENST00000354670	c.528G>T	p.E176D	COSMIC	no weights	PROBABLY DAMAGING
32	JSC1	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000354670	c.238C>A	p.Q80K	COSMIC	no weights	POSSIBLY DAMAGING
33	JURKAT	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000354670	c.363delC	p.E122fs*51	COSMIC	NP	NP
34	KARPAS45	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000354670	c.294C>T	p.G98G	COSMIC	NP	NP
35	KYM1	Cell Line	SOFT_TISSUE	ENST00000354670	c.177C>A	p.G59G	COSMIC	NP	NP
36	LOXIMVI	Cell Line	SKIN	ENST00000354670	c.3G>A	p.M1I	COSMIC	no weights	POSSIBLY DAMAGING
37	NCIH2170	Cell Line	LUNG	ENST00000354670	c.417C>A	p.C139*	COSMIC	NP	NP
38	SLVL	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000354670	c.349G>A	p.G117R	COSMIC	no weights	POSSIBLY DAMAGING
39	SNU1040	Cell Line	LARGE_INTESTINE	ENST00000354670	c.323C>T	p.A108V	COSMIC	no weights	BENIGN
40	SUDHL1	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000354670	c.270G>T	p.E90D	COSMIC	no weights	BENIGN
41	TGBC11TKB	Cell Line	STOMACH	ENST00000354670	c.138A>G	p.R46R	COSMIC	NP	NP
42	HEC108	Cell Line	ENDOMETRIUM	NP_277038	c.410T>A	p.L137H	CCLE	NA	Probably Damaging
43	HEC151	Cell Line	ENDOMETRIUM	NP_277038	c.362_363delCC	p.P121fs	CCLE	NA	NP
44	HPBALL	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_277038	c.421G>A	p.A141T	CCLE	NA	Probably Damaging
45	HT115	Cell Line	LARGE INTESTINE	NP_277038	c.528G>T	p.E176D	CCLE	NA	Probably Damaging
46	JMSU1	Cell Line	URINARY TRACT	NP_277038	c.388G>A	p.E130K	CCLE	NA	Probably Damaging
47	NCIH2170	Cell Line	LUNG	NP_277038	c.417C>A	p.C139*	CCLE	NA	NP
48	REH	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_277038	c.307C>T	p.R103W	CCLE	NA	Probably Damaging
49	SUDHL1	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_277038	c.270G>T	p.E90D	CCLE	NA	Benign
50	585208	Tumour	LUNG	ENST00000354670	c.301G>A	p.G101S	COSMIC	NP	NP
51	587332	Tumour	LARGE INTESTINE	ENST00000354670	c.24G>T	p.E8D	COSMIC	NP	NP
52	CLL040	Tumour	HAEMATOPOIETIC AND LYMPHOID TISSUE	ENST00000354670	c.261G>A	p.G87G	COSMIC	NP	NP
53	HCT-116	Cell Line	LARGE INTESTINE	ENST00000354670	c.65C>T	p.P22L	COSMIC	NP	NP
54	LOXIMVI	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	ENST00000354670	c.3G>A	p.M1I	COSMIC	NP	NP
55	LUAD-S01341	Tumour	LUNG	ENST00000354670	c.453+2T>A	p.?	COSMIC	NP	NP
56	OCC06PT	Tumour	OVARY	ENST00000354670	c.152delC	p.P51fs*38	COSMIC	NP	NP
57	TCGA-A6-3809-01	Tumour	LARGE INTESTINE	ENST00000354670	c.386C>T	p.A129V	COSMIC	NP	NP
58	TCGA-A6-6781-01	Tumour	LARGE INTESTINE	ENST00000354670	c.144G>T	p.Q48H	COSMIC	NP	NP
59	TCGA-AA-3558-01	Tumour	LARGE INTESTINE	ENST00000354670	c.69G>T	p.V23V	COSMIC	NP	NP
60	TCGA-AA-3663-01	Tumour	LARGE INTESTINE	ENST00000354670	c.363delC	p.E122fs*51	COSMIC	NP	NP
61	TCGA-AA-A010-01	Tumour	LARGE INTESTINE	ENST00000354670	c.467A>G	p.Q156R	COSMIC	NP	NP
62	TCGA-AP-A051-01	Tumour	ENDOMETRIUM	ENST00000354670	c.216T>C	p.T72T	COSMIC	NP	NP
63	TCGA-AP-A052-01	Tumour	ENDOMETRIUM	ENST00000354670	c.73C>T	p.Q25*	COSMIC	NP	NP
64	TCGA-B5-A0K6-01	Tumour	ENDOMETRIUM	ENST00000354670	c.14_15delAG	p.Q5fs*8	COSMIC	NP	NP
65	TCGA-D1-A165-01	Tumour	ENDOMETRIUM	ENST00000354670	c.142C>T	p.Q48*	COSMIC	NP	NP
66	TCGA-DK-A1AC-01	Tumour	URINARY TRACT	ENST00000354670	c.412C>T	p.Q138*	COSMIC	NP	NP
67	TCGA-G2-A2EC-01	Tumour	URINARY TRACT	ENST00000354670	c.404G>A	p.R135Q	COSMIC	NP	NP
68	AGS	Cell Line	STOMACH	ENST00000354670	c.293-4G>T	p.?	COSMIC	NP	NP
69	AGS	Cell Line	STOMACH	ENST00000354670	c.7C>A	p.P3T	COSMIC	no weights	POSSIBLY DAMAGING
70	FARAGE	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000354670	c.503A>G	p.H168R	COSMIC	no weights	BENIGN
71	HCT116	Cell Line	LARGE_INTESTINE	ENST00000354670	c.65C>T	p.P22L	COSMIC	no weights	BENIGN
72	HT115	Cell Line	LARGE_INTESTINE	ENST00000354670	c.528G>T	p.E176D	COSMIC	no weights	PROBABLY DAMAGING
73	JSC1	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000354670	c.238C>A	p.Q80K	COSMIC	no weights	POSSIBLY DAMAGING
74	JURKAT	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000354670	c.363delC	p.E122fs*51	COSMIC	NP	NP
75	KARPAS45	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000354670	c.294C>T	p.G98G	COSMIC	NP	NP
76	KYM1	Cell Line	SOFT_TISSUE	ENST00000354670	c.177C>A	p.G59G	COSMIC	NP	NP
77	LOXIMVI	Cell Line	SKIN	ENST00000354670	c.3G>A	p.M1I	COSMIC	no weights	POSSIBLY DAMAGING
78	NCIH2170	Cell Line	LUNG	ENST00000354670	c.417C>A	p.C139*	COSMIC	NP	NP
79	SLVL	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000354670	c.349G>A	p.G117R	COSMIC	no weights	POSSIBLY DAMAGING
80	SNU1040	Cell Line	LARGE_INTESTINE	ENST00000354670	c.323C>T	p.A108V	COSMIC	no weights	BENIGN
81	SUDHL1	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000354670	c.270G>T	p.E90D	COSMIC	no weights	BENIGN
82	TGBC11TKB	Cell Line	STOMACH	ENST00000354670	c.138A>G	p.R46R	COSMIC	NP	NP

*NP: Not Predicted

Tissue Type	Mean Expression Value	Median Expression Value	Mean CNV	Median CNV

AUTONOMIC GANGLIA	6.1326	5.9661	0.0548	0.0446
BILIARY TRACT	6.1873	5.8784	-0.1225	-0.0495
BONE	6.0226	5.591	0.0071	0.0002166
BREAST	5.9717	5.8662	-0.1679	-0.1583
CENTRAL NERVOUS SYSTEM	5.8072	5.6419	0.0043	0.03354
ENDOMETRIUM	5.9687	5.7886	-0.1250	-0.07341
HAEMATOPOIETIC AND LYMPHOID TISSUE	6.5875	6.3577	-0.0024	0.0031
KIDNEY	5.7145	5.6137	-0.0849	-0.0169
LARGE INTESTINE	5.6331	5.57555	-0.0070	-0.0023255
LIVER	6.8868	6.7149	-0.1054	-0.2027
LUNG	6.0406	5.85425	-0.1238	-0.10835
OESOPHAGUS	5.8330	5.59435	-0.1122	-0.0932
OVARY	5.9580	5.7909	-0.1597	-0.06027
PANCREAS	5.8187	5.7458	-0.0554	0.02688
PLEURA	5.4768	5.3772	-0.0913	-0.02034
PROSTATE	5.8606	5.7477	-0.0635	0.04036
SALIVARY GLAND	6.0156	6.0156	-0.2482	-0.2482
SKIN	5.7180	5.7585	-0.0388	0.0066
SMALL INTESTINE	5.5805	5.5805	0.0315	0.03148
SOFT TISSUE	5.9234	5.75765	0.0437	0.00985
STOMACH	5.7602	5.4563	-0.0768	-0.1092
THYROID	5.7035	5.60875	0.0561	0.05744
UPPER AERODIGESTIVE TRACT	6.0322	5.862	0.0192	0.02948
URINARY TRACT	5.8215	5.73545	-0.0434	-0.02445

Domain ID	Domain Name	Start Site	End Site	E-value
PF15185	BMF	6	184	2.7e-71
PF15185	BMF	6	184	2.7e-71

S. No.	Position	Amino acid	Type	Description
1	74	S	Phosphorylation	Phosphoserine
2	74	S	Phosphorylation (MAPK8)	Phosphoserine
3	77	S	Phosphorylation	Phosphoserine
4	77	S	Phosphorylation (MAPK8)	Phosphoserine
5	74	S	Phosphorylation	Phosphoserine
6	74	S	Phosphorylation (MAPK8)	Phosphoserine
7	77	S	Phosphorylation	Phosphoserine
8	77	S	Phosphorylation (MAPK8)	Phosphoserine

Proteomics DB	COSMIC	Gene Atlas	STRING	PIR
BMF	BMF	BMF	ENSP00000346697	Q96LC9
QuickGO	HGNC	Ensembl Genome Browser	TreeFam	UniProt
Q96LC9	BMF	ENSP00000346697	BMF	Q96LC9
Expression Atlas	Protein Atlas	OMIM	IntAct	PharmGKB
BMF	ENSP00000346697	606266	Q96LC9	PA134893658

Protein: BMF

Mutation Data (+)

Copy number variation and expression profile (+)

Gene Essentiality Data (+)

Tertiary structure (+)

Structure Domains (+)

Sequence Alignment (+)

Sequence Profiles (+)

Post Translational Modifications (+)

Other Databases Link (+)

Modelled Structure	Structures available in PDB
	Structure is not available in PDB