ApoCanD

#	Name/ID	Cell Line/Tumor sample	Tissue of Origin	Reference ID	cDNA change	Protein change	Source	FATHMM Prediction	PolyPhen2 Prediction
1	587286	Tumour	LARGE INTESTINE	ENST00000308721	c.781G>A	p.G261R	COSMIC	NP	NP
2	ME009T	Tumour	SKIN	ENST00000308721	c.530C>T	p.S177F	COSMIC	NP	NP
3	ME029T	Tumour	SKIN	ENST00000308721	c.924G>A	p.W308*	COSMIC	NP	NP
4	MZ7-mel	Cell Line	SKIN	ENST00000308721	c.162C>T	p.S54S	COSMIC	NP	NP
5	TCGA-18-4721-01	Tumour	LUNG	ENST00000308721	c.375G>T	p.S125S	COSMIC	NP	NP
6	TCGA-22-0944-01	Tumour	LUNG	ENST00000308721	c.940G>A	p.G314R	COSMIC	NP	NP
7	TCGA-36-2530-01	Tumour	OVARY	ENST00000308721	c.614A>T	p.E205V	COSMIC	NP	NP
8	TCGA-A6-6649-01	Tumour	LARGE INTESTINE	ENST00000308721	c.579C>T	p.H193H	COSMIC	NP	NP
9	TCGA-AA-3663-01	Tumour	LARGE INTESTINE	ENST00000308721	c.161C>A	p.S54Y	COSMIC	NP	NP
10	TCGA-AG-A002-01	Tumour	LARGE INTESTINE	ENST00000308721	c.13A>G	p.S5G	COSMIC	NP	NP
11	TCGA-AP-A051-01	Tumour	ENDOMETRIUM	ENST00000308721	c.850G>T	p.A284S	COSMIC	NP	NP
12	TCGA-AU-6004-01	Tumour	LARGE INTESTINE	ENST00000308721	c.324G>A	p.T108T	COSMIC	NP	NP
13	TCGA-BH-A28Q-01	Tumour	BREAST	ENST00000308721	c.316C>G	p.Q106E	COSMIC	NP	NP
14	TCGA-BS-A0UF-01	Tumour	ENDOMETRIUM	ENST00000308721	c.647T>G	p.L216R	COSMIC	NP	NP
15	TCGA-CA-6717-01	Tumour	LARGE INTESTINE	ENST00000308721	c.314C>T	p.S105L	COSMIC	NP	NP
16	TCGA-CA-6717-01	Tumour	LARGE INTESTINE	ENST00000308721	c.689A>C	p.D230A	COSMIC	NP	NP
17	TCGA-G2-A2EO-01	Tumour	URINARY TRACT	ENST00000308721	c.846C>G	p.L282L	COSMIC	NP	NP
18	TCGA-G4-6293-01	Tumour	LARGE INTESTINE	ENST00000308721	c.765G>A	p.M255I	COSMIC	NP	NP
19	TCGA-GV-A3JW-01	Tumour	URINARY TRACT	ENST00000308721	c.82G>A	p.A28T	COSMIC	NP	NP
20	YUWAND	Tumour	SKIN	ENST00000308721	c.670G>A	p.E224K	COSMIC	NP	NP
21	pfg029T	Tumour	STOMACH	ENST00000308721	c.514G>A	p.A172T	COSMIC	NP	NP
22	A204	Cell Line	SOFT_TISSUE	ENST00000308721	c.757G>A	p.V253I	COSMIC	PASSENGER/OTHER	BENIGN
23	CW2	Cell Line	LARGE_INTESTINE	ENST00000308721	c.3G>A	p.M1I	COSMIC	no weights	PROBABLY DAMAGING
24	DBTRG05MG	Cell Line	CENTRAL_NERVOUS_SYSTEM	ENST00000308721	c.420C>T	p.C140C	COSMIC	NP	NP
25	DJM1	Cell Line	SKIN	ENST00000308721	c.433G>A	p.A145T	COSMIC	no weights	POSSIBLY DAMAGING
26	EMCBAC1	Cell Line	LUNG	ENST00000308721	c.624A>G	p.I208M	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
27	MZ7MEL	Cell Line	SKIN	ENST00000308721	c.162C>T	p.S54S	COSMIC	NP	NP
28	NCIH2110	Cell Line	LUNG	ENST00000308721	c.81C>G	p.L27L	COSMIC	NP	NP
29	NCIH226	Cell Line	LUNG	ENST00000308721	c.457A>G	p.I153V	COSMIC	no weights	PROBABLY DAMAGING
30	OSC20	Cell Line	UPPER_AERODIGESTIVE_TRACT	ENST00000308721	c.893C>G	p.T298S	COSMIC	PASSENGER/OTHER	BENIGN
31	SW48	Cell Line	LARGE_INTESTINE	ENST00000308721	c.432A>T	p.E144D	COSMIC	no weights	BENIGN
32	TE12	Cell Line	OESOPHAGUS	ENST00000308721	c.640G>A	p.E214K	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
33	587286	Tumour	LARGE INTESTINE	ENST00000308721	c.781G>A	p.G261R	COSMIC	NP	NP
34	ME009T	Tumour	SKIN	ENST00000308721	c.530C>T	p.S177F	COSMIC	NP	NP
35	ME029T	Tumour	SKIN	ENST00000308721	c.924G>A	p.W308*	COSMIC	NP	NP
36	MZ7-mel	Cell Line	SKIN	ENST00000308721	c.162C>T	p.S54S	COSMIC	NP	NP
37	TCGA-18-4721-01	Tumour	LUNG	ENST00000308721	c.375G>T	p.S125S	COSMIC	NP	NP
38	TCGA-22-0944-01	Tumour	LUNG	ENST00000308721	c.940G>A	p.G314R	COSMIC	NP	NP
39	TCGA-36-2530-01	Tumour	OVARY	ENST00000308721	c.614A>T	p.E205V	COSMIC	NP	NP
40	TCGA-A6-6649-01	Tumour	LARGE INTESTINE	ENST00000308721	c.579C>T	p.H193H	COSMIC	NP	NP
41	TCGA-AA-3663-01	Tumour	LARGE INTESTINE	ENST00000308721	c.161C>A	p.S54Y	COSMIC	NP	NP
42	TCGA-AG-A002-01	Tumour	LARGE INTESTINE	ENST00000308721	c.13A>G	p.S5G	COSMIC	NP	NP
43	TCGA-AP-A051-01	Tumour	ENDOMETRIUM	ENST00000308721	c.850G>T	p.A284S	COSMIC	NP	NP
44	TCGA-AU-6004-01	Tumour	LARGE INTESTINE	ENST00000308721	c.324G>A	p.T108T	COSMIC	NP	NP
45	TCGA-BH-A28Q-01	Tumour	BREAST	ENST00000308721	c.316C>G	p.Q106E	COSMIC	NP	NP
46	TCGA-BS-A0UF-01	Tumour	ENDOMETRIUM	ENST00000308721	c.647T>G	p.L216R	COSMIC	NP	NP
47	TCGA-CA-6717-01	Tumour	LARGE INTESTINE	ENST00000308721	c.314C>T	p.S105L	COSMIC	NP	NP
48	TCGA-CA-6717-01	Tumour	LARGE INTESTINE	ENST00000308721	c.689A>C	p.D230A	COSMIC	NP	NP
49	TCGA-G2-A2EO-01	Tumour	URINARY TRACT	ENST00000308721	c.846C>G	p.L282L	COSMIC	NP	NP
50	TCGA-G4-6293-01	Tumour	LARGE INTESTINE	ENST00000308721	c.765G>A	p.M255I	COSMIC	NP	NP
51	TCGA-GV-A3JW-01	Tumour	URINARY TRACT	ENST00000308721	c.82G>A	p.A28T	COSMIC	NP	NP
52	YUWAND	Tumour	SKIN	ENST00000308721	c.670G>A	p.E224K	COSMIC	NP	NP
53	pfg029T	Tumour	STOMACH	ENST00000308721	c.514G>A	p.A172T	COSMIC	NP	NP
54	A204	Cell Line	SOFT_TISSUE	ENST00000308721	c.757G>A	p.V253I	COSMIC	PASSENGER/OTHER	BENIGN
55	CW2	Cell Line	LARGE_INTESTINE	ENST00000308721	c.3G>A	p.M1I	COSMIC	no weights	PROBABLY DAMAGING
56	DBTRG05MG	Cell Line	CENTRAL_NERVOUS_SYSTEM	ENST00000308721	c.420C>T	p.C140C	COSMIC	NP	NP
57	DJM1	Cell Line	SKIN	ENST00000308721	c.433G>A	p.A145T	COSMIC	no weights	POSSIBLY DAMAGING
58	EMCBAC1	Cell Line	LUNG	ENST00000308721	c.624A>G	p.I208M	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
59	MZ7MEL	Cell Line	SKIN	ENST00000308721	c.162C>T	p.S54S	COSMIC	NP	NP
60	NCIH2110	Cell Line	LUNG	ENST00000308721	c.81C>G	p.L27L	COSMIC	NP	NP
61	NCIH226	Cell Line	LUNG	ENST00000308721	c.457A>G	p.I153V	COSMIC	no weights	PROBABLY DAMAGING
62	OSC20	Cell Line	UPPER_AERODIGESTIVE_TRACT	ENST00000308721	c.893C>G	p.T298S	COSMIC	PASSENGER/OTHER	BENIGN
63	SW48	Cell Line	LARGE_INTESTINE	ENST00000308721	c.432A>T	p.E144D	COSMIC	no weights	BENIGN
64	TE12	Cell Line	OESOPHAGUS	ENST00000308721	c.640G>A	p.E214K	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING

*NP: Not Predicted

Tissue Type	Mean Expression Value	Median Expression Value	Mean CNV	Median CNV

AUTONOMIC GANGLIA	4.6964	4.7087	0.0584	-0.01934
BILIARY TRACT	6.6671	5.181	0.5649	0.0709
BONE	4.7298	4.6879	0.0938	0.0133
BREAST	4.9986	4.79165	0.0218	0.00015
CENTRAL NERVOUS SYSTEM	4.6904	4.7034	-0.0941	-0.0606
ENDOMETRIUM	4.8061	4.7614	-0.0165	-0.01213
HAEMATOPOIETIC AND LYMPHOID TISSUE	4.9314	4.8715	-0.1022	0.0063
KIDNEY	4.7410	4.6623	0.1889	0.1015
LARGE INTESTINE	6.9315	7.16625	0.1228	0.05225
LIVER	4.9021	4.7589	0.0182	0.1368
LUNG	4.8085	4.77495	0.0694	0.05305
OESOPHAGUS	5.0488	4.9328	0.2239	0.3063
OVARY	4.9511	4.7692	-0.0253	0.0302
PANCREAS	5.6188	5.1686	0.1129	0.1762
PLEURA	4.6968	4.6104	0.0796	0.0271
PROSTATE	4.8714	4.83285	-0.1368	-0.14475
SALIVARY GLAND	4.5399	4.5399	-0.3905	-0.3905
SKIN	4.6439	4.6332	0.0441	0.0083
SMALL INTESTINE	4.7886	4.7886	0.0026	0.0026
SOFT TISSUE	4.7470	4.6892	-0.0574	-0.0141
STOMACH	5.8933	5.06635	0.0042	0.004325
THYROID	4.6793	4.66355	-0.0499	-0.0565
UPPER AERODIGESTIVE TRACT	5.1714	4.94365	0.1560	0.15435
URINARY TRACT	4.9367	4.7556	0.1544	0.1997

Proteomics DB	COSMIC	Gene Atlas	STRING	PIR
BCL2L14	BCL2L14	BCL2L14	ENSP00000266434	Q9BZR8
QuickGO	HGNC	Ensembl Genome Browser	TreeFam	UniProt
Q9BZR8	BCL2L14	ENSP00000266434	BCL2L14	Q9BZR8
Expression Atlas	Protein Atlas	OMIM	IntAct	PharmGKB
BCL2L14	ENSP00000266434	606126	Q9BZR8	PA134870762

Protein: BCL2L14

Mutation Data (+)

Copy number variation and expression profile (+)

Gene Essentiality Data (+)

Tertiary structure (+)

Structure Domains (+)

Sequence Alignment (+)

Sequence Profiles (+)

Post Translational Modifications (+)

Other Databases Link (+)

Modelled Structure	Structures available in PDB
	Structure is not available in PDB