ApoCanD

#	Name/ID	Cell Line/Tumor sample	Tissue of Origin	Reference ID	cDNA change	Protein change	Source	FATHMM Prediction	PolyPhen2 Prediction
1	22RV1	Cell Line	PROSTATE	NP_004315	c.114_115delGG	p.M38fs	CCLE	NP	NP
2	AN3CA	Cell Line	ENDOMETRIUM	NP_004315	c.543_544insC	p.L181fs	CCLE	NP	NP
3	CMLT1	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
4	CMLT1	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_004315	c.389C>T	p.P130L	CCLE	PASSENGER/OTHER	Probably Damaging
5	COLO684	Cell Line	ENDOMETRIUM	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
6	COLO704	Cell Line	OVARY	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
7	CW2	Cell Line	LARGE INTESTINE	NP_004315	c.369_splice	p.K123_splice	CCLE	NP	NP
8	DAUDI	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_004315	c.323G>T	p.G108V	CCLE	CANCER	Probably Damaging
9	EFO27	Cell Line	OVARY	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
10	HCC1500	Cell Line	BREAST	NP_004315	c.638C>T	p.A213V	CCLE	NP	NP
11	HCT116	Cell Line	LARGE INTESTINE	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
12	HEC265	Cell Line	ENDOMETRIUM	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
13	HEC59	Cell Line	ENDOMETRIUM	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
14	HEC6	Cell Line	ENDOMETRIUM	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
15	HPBALL	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_004315	c.199G>A	p.G67R	CCLE	PASSENGER/OTHER	Probably Damaging
16	HPBALL	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_004315	c.508C>T	p.R170C	CCLE	NP	NP
17	IM95	Cell Line	STOMACH	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
18	KM12	Cell Line	LARGE INTESTINE	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
19	KNS62	Cell Line	LUNG	NP_004315	c.199G>A	p.G67R	CCLE	PASSENGER/OTHER	Probably Damaging
20	LOVO	Cell Line	LARGE INTESTINE	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
21	LS180	Cell Line	LARGE INTESTINE	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
22	MDAPCA2B	Cell Line	PROSTATE	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
23	MFE296	Cell Line	ENDOMETRIUM	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
24	NALM6	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_004315	c.100C>T	p.R34*	CCLE	NP	NP
25	NALM6	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
26	OVK18	Cell Line	OVARY	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
27	RL952	Cell Line	ENDOMETRIUM	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
28	SNU1040	Cell Line	LARGE INTESTINE	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
29	SNU1040	Cell Line	LARGE INTESTINE	NP_004315	c.92T>C	p.I31T	CCLE	PASSENGER/OTHER	Possibly Damaging
30	SNU324	Cell Line	PANCREAS	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
31	SNU520	Cell Line	STOMACH	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
32	SNU81	Cell Line	LARGE INTESTINE	NP_004315	c.223G>A	p.E75K	CCLE	PASSENGER/OTHER	Possibly Damaging
33	SNUC4	Cell Line	LARGE INTESTINE	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
34	SNUC5	Cell Line	LARGE INTESTINE	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
35	VMCUB1	Cell Line	URINARY TRACT	NP_004315	c.247G>A	p.V83M	CCLE	PASSENGER/OTHER	Probably Damaging
36	GDM1	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_620116	c.500C>T	p.T167M	CCLE	PASSENGER/OTHER	Probably Damaging
37	RCHACV	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_620116	c.563G>A	p.W188*	CCLE	NP	NP
38	16792	Tumour	LUNG	ENST00000293288	c.280C>T	p.R94*	COSMIC	NP	NP
39	340TS	Tumour	ENDOMETRIUM	ENST00000293288	c.109C>T	p.R37*	COSMIC	NP	NP
40	587220	Tumour	LARGE INTESTINE	ENST00000293288	c.338T>C	p.L113P	COSMIC	NP	NP
41	587256	Tumour	LARGE INTESTINE	ENST00000293288	c.373C>A	p.L125M	COSMIC	NP	NP
42	BN24T	Tumour	LIVER	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
43	CP66-MEL	Cell Line	SKIN	ENST00000293288	c.120G>A	p.G40G	COSMIC	NP	NP
44	LAU108	Cell Line	SKIN	ENST00000293288	c.71C>T	p.A24V	COSMIC	NP	NP
45	S00501	Tumour	LUNG	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
46	TCGA-02-0055-01	Tumour	CENTRAL NERVOUS SYSTEM	ENST00000293288	c.29G>A	p.G10D	COSMIC	NP	NP
47	TCGA-44-2662-01	Tumour	LUNG	ENST00000293288	c.353G>T	p.S118I	COSMIC	NP	NP
48	TCGA-A6-5657-01	Tumour	LARGE INTESTINE	ENST00000293288	c.399C>G	p.I133M	COSMIC	NP	NP
49	TCGA-A6-5661-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
50	TCGA-A6-5665-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
51	TCGA-A6-6781-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
52	TCGA-AA-3679-01	Tumour	LARGE INTESTINE	ENST00000293288	c.417G>T	p.W139C	COSMIC	NP	NP
53	TCGA-AD-5900-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
54	TCGA-AD-5900-01	Tumour	LARGE INTESTINE	ENST00000293288	c.120G>A	p.G40G	COSMIC	NP	NP
55	TCGA-AD-6889-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
56	TCGA-AD-6889-01	Tumour	LARGE INTESTINE	ENST00000293288	c.84delG	p.G29fs*31	COSMIC	NP	NP
57	TCGA-AP-A059-01	Tumour	ENDOMETRIUM	ENST00000293288	c.545C>T	p.P182L	COSMIC	NP	NP
58	TCGA-AY-6197-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
59	TCGA-AZ-6598-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
60	TCGA-AZ-6598-01	Tumour	LARGE INTESTINE	ENST00000293288	c.282A>G	p.R94R	COSMIC	NP	NP
61	TCGA-BS-A0UV-01	Tumour	ENDOMETRIUM	ENST00000293288	c.266G>A	p.R89Q	COSMIC	NP	NP
62	TCGA-BT-A20J-01	Tumour	URINARY TRACT	ENST00000293288	c.432C>T	p.L144L	COSMIC	NP	NP
63	TCGA-BT-A20J-01	Tumour	URINARY TRACT	ENST00000293288	c.82C>T	p.Q28*	COSMIC	NP	NP
64	TCGA-CA-6715-01	Tumour	LARGE INTESTINE	ENST00000293288	c.280C>A	p.R94R	COSMIC	NP	NP
65	TCGA-CM-4743-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
66	TCGA-CM-4746-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
67	TCGA-CM-6171-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
68	TCGA-D1-A101-01	Tumour	ENDOMETRIUM	ENST00000293288	c.442C>T	p.L148L	COSMIC	NP	NP
69	TCGA-D5-6928-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
70	TCGA-DC-5337-01	Tumour	LARGE INTESTINE	ENST00000293288	c.119G>A	p.G40E	COSMIC	NP	NP
71	TCGA-E9-A1NC-01	Tumour	BREAST	ENST00000293288	c.113_114insG	p.E41fs*33	COSMIC	NP	NP
72	TCGA-E9-A1NI-01	Tumour	BREAST	ENST00000293288	c.113_114insG	p.E41fs*33	COSMIC	NP	NP
73	TCGA-EI-6507-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
74	TCGA-G4-6588-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
75	22RV1	Cell Line	PROSTATE	ENST00000293288	c.114_115delGG	p.E41fs*32	COSMIC	NP	NP
76	AN3CA	Cell Line	ENDOMETRIUM	ENST00000293288	c.543_544insC	p.A184fs*29	COSMIC	NP	NP
77	ASH3	Cell Line	THYROID	ENST00000293288	c.233G>T	p.R78M	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
78	CAL78	Cell Line	BONE	ENST00000293288	c.252C>T	p.D84D	COSMIC	NP	NP
79	CMLT1	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000293288	c.389C>T	p.P130L	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
80	COLO684	Cell Line	ENDOMETRIUM	ENST00000293288	c.121_122insG	p.E41fs*33	COSMIC	NP	NP
81	CP66MEL	Cell Line	SKIN	ENST00000293288	c.120G>A	p.G40G	COSMIC	NP	NP
82	CTB1	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000293288	c.121_122insG	p.E41fs*33	COSMIC	NP	NP
83	CW2	Cell Line	LARGE_INTESTINE	ENST00000293288	c.369+1G>A	p.?	COSMIC	NP	NP
84	DAUDI	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000293288	c.323G>T	p.G108V	COSMIC	CANCER	PROBABLY DAMAGING
85	DU145	Cell Line	PROSTATE	ENST00000293288	c.121_122insG	p.E41fs*33	COSMIC	NP	NP
86	GP5D	Cell Line	LARGE_INTESTINE	ENST00000293288	c.121_122insG	p.E41fs*33	COSMIC	NP	NP
87	GRST	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000293288	c.260delC	p.R89fs*44	COSMIC	NP	NP
88	H2373	Cell Line	PLEURA	ENST00000293288	c.624T>A	p.D208E	COSMIC	NP	NP
89	H2461	Cell Line	PLEURA	ENST00000293288	c.584G>C	p.R195T	COSMIC	NP	NP
90	HCC1500	Cell Line	BREAST	ENST00000293288	c.638C>T	p.A213V	COSMIC	NP	NP
91	HCC56	Cell Line	LARGE_INTESTINE	ENST00000293288	c.585G>A	p.R195R	COSMIC	NP	NP
92	HCT15	Cell Line	LARGE_INTESTINE	ENST00000293288	c.430C>A	p.L144I	COSMIC	PASSENGER/OTHER	BENIGN
93	HT55	Cell Line	LARGE_INTESTINE	ENST00000293288	c.406A>C	p.I136L	COSMIC	PASSENGER/OTHER	BENIGN
94	JIYOYEP2003	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000293288	c.640T>C	p.F214L	COSMIC	NP	NP
95	KARPAS45	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000293288	c.457C>T	p.Q153*	COSMIC	NP	NP
96	KM12	Cell Line	LARGE_INTESTINE	ENST00000293288	c.121_122insG	p.E41fs*33	COSMIC	NP	NP
97	KMS11	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000293288	c.116G>C	p.G39A	COSMIC	PASSENGER/OTHER	BENIGN
98	KNS62	Cell Line	LUNG	ENST00000293288	c.199G>A	p.G67R	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
99	KYAE1	Cell Line	OESOPHAGUS	ENST00000293288	c.420A>G	p.T140T	COSMIC	NP	NP
100	LOVO	Cell Line	LARGE_INTESTINE	ENST00000293288	c.121_122insG	p.E41fs*33	COSMIC	NP	NP
101	MCIXC	Cell Line	AUTONOMIC_GANGLIA	ENST00000293288	c.121_122insG	p.E41fs*33	COSMIC	NP	NP
102	MN60	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000293288	c.199G>A	p.G67R	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
103	MSTO211H	Cell Line	PLEURA	ENST00000293288	c.639G>A	p.A213A	COSMIC	NP	NP
104	NCIH250	Cell Line	LUNG	ENST00000293288	c.390G>A	p.P130P	COSMIC	NP	NP
105	OCIAML3	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000293288	c.121_122insG	p.E41fs*33	COSMIC	NP	NP
106	P12ICHIKAWA	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000293288	c.642T>C	p.F214F	COSMIC	NP	NP
107	P31FUJ	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000293288	c.121_122insG	p.E41fs*33	COSMIC	NP	NP
108	SKUT1	Cell Line	SOFT_TISSUE	ENST00000293288	c.121_122insG	p.E41fs*33	COSMIC	NP	NP
109	SNU81	Cell Line	LARGE_INTESTINE	ENST00000293288	c.223G>A	p.E75K	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
110	STS0421	Cell Line	SOFT_TISSUE	ENST00000293288	c.125C>T	p.A42V	COSMIC	PASSENGER/OTHER	BENIGN
111	TE15	Cell Line	OESOPHAGUS	ENST00000293288	c.262C>T	p.P88S	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
112	UDSCC2	Cell Line	UPPER_AERODIGESTIVE_TRACT	ENST00000293288	c.486C>T	p.L162L	COSMIC	NP	NP
113	UDSCC2	Cell Line	UPPER_AERODIGESTIVE_TRACT	ENST00000293288	c.601C>T	p.L201F	COSMIC	NP	NP
114	VMCUB1	Cell Line	URINARY_TRACT	ENST00000293288	c.247G>A	p.V83M	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
115	22RV1	Cell Line	PROSTATE	NP_004315	c.114_115delGG	p.M38fs	CCLE	NP	NP
116	AN3CA	Cell Line	ENDOMETRIUM	NP_004315	c.543_544insC	p.L181fs	CCLE	NP	NP
117	CMLT1	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
118	CMLT1	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_004315	c.389C>T	p.P130L	CCLE	PASSENGER/OTHER	Probably Damaging
119	COLO684	Cell Line	ENDOMETRIUM	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
120	COLO704	Cell Line	OVARY	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
121	CW2	Cell Line	LARGE INTESTINE	NP_004315	c.369_splice	p.K123_splice	CCLE	NP	NP
122	DAUDI	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_004315	c.323G>T	p.G108V	CCLE	CANCER	Probably Damaging
123	EFO27	Cell Line	OVARY	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
124	HCC1500	Cell Line	BREAST	NP_004315	c.638C>T	p.A213V	CCLE	NP	NP
125	HCT116	Cell Line	LARGE INTESTINE	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
126	HEC265	Cell Line	ENDOMETRIUM	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
127	HEC59	Cell Line	ENDOMETRIUM	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
128	HEC6	Cell Line	ENDOMETRIUM	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
129	HPBALL	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_004315	c.199G>A	p.G67R	CCLE	PASSENGER/OTHER	Probably Damaging
130	HPBALL	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_004315	c.508C>T	p.R170C	CCLE	NP	NP
131	IM95	Cell Line	STOMACH	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
132	KM12	Cell Line	LARGE INTESTINE	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
133	KNS62	Cell Line	LUNG	NP_004315	c.199G>A	p.G67R	CCLE	PASSENGER/OTHER	Probably Damaging
134	LOVO	Cell Line	LARGE INTESTINE	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
135	LS180	Cell Line	LARGE INTESTINE	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
136	MDAPCA2B	Cell Line	PROSTATE	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
137	MFE296	Cell Line	ENDOMETRIUM	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
138	NALM6	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_004315	c.100C>T	p.R34*	CCLE	NP	NP
139	NALM6	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
140	OVK18	Cell Line	OVARY	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
141	RL952	Cell Line	ENDOMETRIUM	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
142	SNU1040	Cell Line	LARGE INTESTINE	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
143	SNU1040	Cell Line	LARGE INTESTINE	NP_004315	c.92T>C	p.I31T	CCLE	PASSENGER/OTHER	Possibly Damaging
144	SNU324	Cell Line	PANCREAS	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
145	SNU520	Cell Line	STOMACH	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
146	SNU81	Cell Line	LARGE INTESTINE	NP_004315	c.223G>A	p.E75K	CCLE	PASSENGER/OTHER	Possibly Damaging
147	SNUC4	Cell Line	LARGE INTESTINE	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
148	SNUC5	Cell Line	LARGE INTESTINE	NP_004315	c.114_114delG	p.M38fs	CCLE	NP	NP
149	VMCUB1	Cell Line	URINARY TRACT	NP_004315	c.247G>A	p.V83M	CCLE	PASSENGER/OTHER	Probably Damaging
150	GDM1	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_620116	c.500C>T	p.T167M	CCLE	PASSENGER/OTHER	Probably Damaging
151	RCHACV	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_620116	c.563G>A	p.W188*	CCLE	NP	NP
152	16792	Tumour	LUNG	ENST00000293288	c.280C>T	p.R94*	COSMIC	NP	NP
153	340TS	Tumour	ENDOMETRIUM	ENST00000293288	c.109C>T	p.R37*	COSMIC	NP	NP
154	587220	Tumour	LARGE INTESTINE	ENST00000293288	c.338T>C	p.L113P	COSMIC	NP	NP
155	587256	Tumour	LARGE INTESTINE	ENST00000293288	c.373C>A	p.L125M	COSMIC	NP	NP
156	BN24T	Tumour	LIVER	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
157	CP66-MEL	Cell Line	SKIN	ENST00000293288	c.120G>A	p.G40G	COSMIC	NP	NP
158	LAU108	Cell Line	SKIN	ENST00000293288	c.71C>T	p.A24V	COSMIC	NP	NP
159	S00501	Tumour	LUNG	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
160	TCGA-02-0055-01	Tumour	CENTRAL NERVOUS SYSTEM	ENST00000293288	c.29G>A	p.G10D	COSMIC	NP	NP
161	TCGA-44-2662-01	Tumour	LUNG	ENST00000293288	c.353G>T	p.S118I	COSMIC	NP	NP
162	TCGA-A6-5657-01	Tumour	LARGE INTESTINE	ENST00000293288	c.399C>G	p.I133M	COSMIC	NP	NP
163	TCGA-A6-5661-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
164	TCGA-A6-5665-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
165	TCGA-A6-6781-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
166	TCGA-AA-3679-01	Tumour	LARGE INTESTINE	ENST00000293288	c.417G>T	p.W139C	COSMIC	NP	NP
167	TCGA-AD-5900-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
168	TCGA-AD-5900-01	Tumour	LARGE INTESTINE	ENST00000293288	c.120G>A	p.G40G	COSMIC	NP	NP
169	TCGA-AD-6889-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
170	TCGA-AD-6889-01	Tumour	LARGE INTESTINE	ENST00000293288	c.84delG	p.G29fs*31	COSMIC	NP	NP
171	TCGA-AP-A059-01	Tumour	ENDOMETRIUM	ENST00000293288	c.545C>T	p.P182L	COSMIC	NP	NP
172	TCGA-AY-6197-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
173	TCGA-AZ-6598-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
174	TCGA-AZ-6598-01	Tumour	LARGE INTESTINE	ENST00000293288	c.282A>G	p.R94R	COSMIC	NP	NP
175	TCGA-BS-A0UV-01	Tumour	ENDOMETRIUM	ENST00000293288	c.266G>A	p.R89Q	COSMIC	NP	NP
176	TCGA-BT-A20J-01	Tumour	URINARY TRACT	ENST00000293288	c.432C>T	p.L144L	COSMIC	NP	NP
177	TCGA-BT-A20J-01	Tumour	URINARY TRACT	ENST00000293288	c.82C>T	p.Q28*	COSMIC	NP	NP
178	TCGA-CA-6715-01	Tumour	LARGE INTESTINE	ENST00000293288	c.280C>A	p.R94R	COSMIC	NP	NP
179	TCGA-CM-4743-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
180	TCGA-CM-4746-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
181	TCGA-CM-6171-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
182	TCGA-D1-A101-01	Tumour	ENDOMETRIUM	ENST00000293288	c.442C>T	p.L148L	COSMIC	NP	NP
183	TCGA-D5-6928-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
184	TCGA-DC-5337-01	Tumour	LARGE INTESTINE	ENST00000293288	c.119G>A	p.G40E	COSMIC	NP	NP
185	TCGA-E9-A1NC-01	Tumour	BREAST	ENST00000293288	c.113_114insG	p.E41fs*33	COSMIC	NP	NP
186	TCGA-E9-A1NI-01	Tumour	BREAST	ENST00000293288	c.113_114insG	p.E41fs*33	COSMIC	NP	NP
187	TCGA-EI-6507-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
188	TCGA-G4-6588-01	Tumour	LARGE INTESTINE	ENST00000293288	c.114delG	p.E41fs*19	COSMIC	NP	NP
189	22RV1	Cell Line	PROSTATE	ENST00000293288	c.114_115delGG	p.E41fs*32	COSMIC	NP	NP
190	AN3CA	Cell Line	ENDOMETRIUM	ENST00000293288	c.543_544insC	p.A184fs*29	COSMIC	NP	NP
191	ASH3	Cell Line	THYROID	ENST00000293288	c.233G>T	p.R78M	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
192	CAL78	Cell Line	BONE	ENST00000293288	c.252C>T	p.D84D	COSMIC	NP	NP
193	CMLT1	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000293288	c.389C>T	p.P130L	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
194	COLO684	Cell Line	ENDOMETRIUM	ENST00000293288	c.121_122insG	p.E41fs*33	COSMIC	NP	NP
195	CP66MEL	Cell Line	SKIN	ENST00000293288	c.120G>A	p.G40G	COSMIC	NP	NP
196	CTB1	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000293288	c.121_122insG	p.E41fs*33	COSMIC	NP	NP
197	CW2	Cell Line	LARGE_INTESTINE	ENST00000293288	c.369+1G>A	p.?	COSMIC	NP	NP
198	DAUDI	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000293288	c.323G>T	p.G108V	COSMIC	CANCER	PROBABLY DAMAGING
199	DU145	Cell Line	PROSTATE	ENST00000293288	c.121_122insG	p.E41fs*33	COSMIC	NP	NP
200	GP5D	Cell Line	LARGE_INTESTINE	ENST00000293288	c.121_122insG	p.E41fs*33	COSMIC	NP	NP
201	GRST	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000293288	c.260delC	p.R89fs*44	COSMIC	NP	NP
202	H2373	Cell Line	PLEURA	ENST00000293288	c.624T>A	p.D208E	COSMIC	NP	NP
203	H2461	Cell Line	PLEURA	ENST00000293288	c.584G>C	p.R195T	COSMIC	NP	NP
204	HCC1500	Cell Line	BREAST	ENST00000293288	c.638C>T	p.A213V	COSMIC	NP	NP
205	HCC56	Cell Line	LARGE_INTESTINE	ENST00000293288	c.585G>A	p.R195R	COSMIC	NP	NP
206	HCT15	Cell Line	LARGE_INTESTINE	ENST00000293288	c.430C>A	p.L144I	COSMIC	PASSENGER/OTHER	BENIGN
207	HT55	Cell Line	LARGE_INTESTINE	ENST00000293288	c.406A>C	p.I136L	COSMIC	PASSENGER/OTHER	BENIGN
208	JIYOYEP2003	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000293288	c.640T>C	p.F214L	COSMIC	NP	NP
209	KARPAS45	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000293288	c.457C>T	p.Q153*	COSMIC	NP	NP
210	KM12	Cell Line	LARGE_INTESTINE	ENST00000293288	c.121_122insG	p.E41fs*33	COSMIC	NP	NP
211	KMS11	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000293288	c.116G>C	p.G39A	COSMIC	PASSENGER/OTHER	BENIGN
212	KNS62	Cell Line	LUNG	ENST00000293288	c.199G>A	p.G67R	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
213	KYAE1	Cell Line	OESOPHAGUS	ENST00000293288	c.420A>G	p.T140T	COSMIC	NP	NP
214	LOVO	Cell Line	LARGE_INTESTINE	ENST00000293288	c.121_122insG	p.E41fs*33	COSMIC	NP	NP
215	MCIXC	Cell Line	AUTONOMIC_GANGLIA	ENST00000293288	c.121_122insG	p.E41fs*33	COSMIC	NP	NP
216	MN60	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000293288	c.199G>A	p.G67R	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
217	MSTO211H	Cell Line	PLEURA	ENST00000293288	c.639G>A	p.A213A	COSMIC	NP	NP
218	NCIH250	Cell Line	LUNG	ENST00000293288	c.390G>A	p.P130P	COSMIC	NP	NP
219	OCIAML3	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000293288	c.121_122insG	p.E41fs*33	COSMIC	NP	NP
220	P12ICHIKAWA	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000293288	c.642T>C	p.F214F	COSMIC	NP	NP
221	P31FUJ	Cell Line	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	ENST00000293288	c.121_122insG	p.E41fs*33	COSMIC	NP	NP
222	SKUT1	Cell Line	SOFT_TISSUE	ENST00000293288	c.121_122insG	p.E41fs*33	COSMIC	NP	NP
223	SNU81	Cell Line	LARGE_INTESTINE	ENST00000293288	c.223G>A	p.E75K	COSMIC	PASSENGER/OTHER	POSSIBLY DAMAGING
224	STS0421	Cell Line	SOFT_TISSUE	ENST00000293288	c.125C>T	p.A42V	COSMIC	PASSENGER/OTHER	BENIGN
225	TE15	Cell Line	OESOPHAGUS	ENST00000293288	c.262C>T	p.P88S	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING
226	UDSCC2	Cell Line	UPPER_AERODIGESTIVE_TRACT	ENST00000293288	c.486C>T	p.L162L	COSMIC	NP	NP
227	UDSCC2	Cell Line	UPPER_AERODIGESTIVE_TRACT	ENST00000293288	c.601C>T	p.L201F	COSMIC	NP	NP
228	VMCUB1	Cell Line	URINARY_TRACT	ENST00000293288	c.247G>A	p.V83M	COSMIC	PASSENGER/OTHER	PROBABLY DAMAGING

*NP: Not Predicted

Tissue Type	Mean Expression Value	Median Expression Value	Mean CNV	Median CNV

AUTONOMIC GANGLIA	7.8666	7.9704	-0.1105	-0.0487
BILIARY TRACT	7.8107	7.9953	0.2426	0.2693
BONE	8.0621	8.1309	-0.0339	-0.0006187
BREAST	7.7649	8.1064	0.0184	0.068515
CENTRAL NERVOUS SYSTEM	8.0286	7.8122	-0.0649	-0.0507
ENDOMETRIUM	7.8080	7.782	-0.0051	-0.0034
HAEMATOPOIETIC AND LYMPHOID TISSUE	8.0378	7.9965	0.0362	0.01098
KIDNEY	8.5865	8.5211	0.0031	0.0294
LARGE INTESTINE	7.7280	7.70415	-0.0066	-0.010745
LIVER	8.0338	8.1051	0.0771	0.1176
LUNG	7.6918	7.7435	0.0052	0.0102815
OESOPHAGUS	7.5246	7.674	0.0372	0.081115
OVARY	7.5815	7.4154	-0.0081	0.01927
PANCREAS	7.7453	7.7202	-0.0603	-0.03163
PLEURA	7.8717	7.8559	0.0316	0.06694
PROSTATE	7.3863	7.5059	-0.3737	-0.4223
SALIVARY GLAND	7.5649	7.5649	0.0672	0.06719
SKIN	8.2085	8.3539	-0.0420	-0.006964
SMALL INTESTINE	9.3970	9.397	0.0544	0.0544
SOFT TISSUE	8.2047	8.4026	0.0171	0.0184
STOMACH	8.2639	8.2596	0.1074	0.02225
THYROID	7.5720	7.6264	0.1401	0.09035
UPPER AERODIGESTIVE TRACT	6.8528	6.8076	-0.0752	-0.033386
URINARY TRACT	8.0157	8.20145	-0.0281	-0.0521

Domain ID	Domain Name	Start Site	End Site	E-value
PF00452	Bcl-2	63	158	5.6e-24
PF00452	Bcl-2	63	158	5.6e-24

Domain ID	Start Site	End Site	E-value
0037326	1	191	3.40e-55
0037326	1	191	3.40e-55

S. No.	Position	Amino acid	Type	Description
1	1	M	Acetylation	N-acetylmethionine.
2	135	T	Phosphorylation	Phosphothreonine
3	140	T	Phosphorylation	Phosphothreonine
4	163	S	Phosphorylation	Phosphoserine
5	167	T	Phosphorylation	Phosphothreonine
6	184	S	Phosphorylation	Phosphoserine
7	21	K	Ubiquitylation	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)
8	57	K	Ubiquitylation	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)
9	60	S	Phosphorylation	Phosphoserine
10	87	S	Phosphorylation	Phosphoserine
11	1	M	Acetylation	N-acetylmethionine.
12	135	T	Phosphorylation	Phosphothreonine
13	140	T	Phosphorylation	Phosphothreonine
14	163	S	Phosphorylation	Phosphoserine
15	167	T	Phosphorylation	Phosphothreonine
16	184	S	Phosphorylation	Phosphoserine
17	21	K	Ubiquitylation	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)
18	57	K	Ubiquitylation	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)
19	60	S	Phosphorylation	Phosphoserine
20	87	S	Phosphorylation	Phosphoserine

Proteomics DB	COSMIC	Gene Atlas	STRING	PIR
BAX	BAX	BAX	ENSP00000293288	Q07812
QuickGO	HGNC	Ensembl Genome Browser	TreeFam	UniProt
Q07812	BAX	ENSP00000293288	BAX	Q07812
Expression Atlas	Protein Atlas	OMIM	IntAct	PharmGKB
BAX	ENSP00000293288	600040	Q07812	PA25269

Protein: BAX

Mutation Data (+)

Copy number variation and expression profile (+)

Gene Essentiality Data (+)

Tertiary structure (+)

Structure Domains (+)

Sequence Alignment (+)

Sequence Profiles (+)

Post Translational Modifications (+)

Other Databases Link (+)

Modelled Structure	Structures available in PDB
	1F16, 2G5B, 2K7W, 2LR1, 3PK1, 3PL7, 4BD2, 4BD6, 4BD7, 4BD8, 4BDU