Middle East respiratory syndrome (MERS)
Middle East respiratory syndrome (MERS) is a viral respiratory disease caused by a novel coronavirus (Middle East respiratory syndrome coronavirus, or MERS‐CoV) that was first identified in Saudi Arabia in 2012.Typical MERS symptoms include fever, cough and shortness of breath. Pneumonia is common, but not always present.Approximately 35% of reported patients with MERS-CoV infection have died.
| Detailed Information |
| Disease Name |
MERS |
| Virus Name |
MERS-CoV virus |
| Capsid Symmetry |
Helical |
| Capsid Naked/Enveloped |
Enveloped |
| Family |
Coronaviridae |
| Genus |
Betacoronavirus |
| Genome |
Single-strand RNA |
| Proteome |
10 predicted open reading frames (ORFs). The ORFs for the structural proteins are arranged as 5′-ORF1a/b-S-E-M-N-poly(A)-3′ and carries genes encoding accessory proteins (APs; 3, 4a, 4b, and 5) |
| Antigenic Target |
Spike glycoprotein (S) |
| Incubation Period |
Approximately 5 days (range 2-14 days) |
| Zoonotic Evidence |
Zoonosis |
| Host |
Human, Tomb bat |
| Chronology_Time |
2012 |
| Regions Affected |
Saudi Arabia, United Arab Emirates, The Republic of Korea, Middle East and Africa |
| Susceptible Age Group |
People belonging 41–60 age group |
| Transmission Route |
Respiratory infection, close contact |
| Symptoms |
Fever, cough and shortness of breath |
| Co-infection |
NA |
| Genome Reference |
Genome
Link |
| Proteome Reference |
Proteome Link |
| Reference |
Reference
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