ViralVacDB | Details of Viral Vaccine

Rabies

A deadly virus spread to people from the saliva of infected animals. Rabies is usually transmitted through an animal bite, for example, from stray dogs. Symptoms include fever, headache, excess salivation, muscle spasms, paralysis and mental confusion. Seek immediate medical attention after a bite or suspected bite. There is no specific treatment for rabies. Once symptoms appear, it's nearly always fatal.
Detailed Information
Disease Name Rabies
Virus Name Rabies virus
Capsid Symmetry Bullet-shaped
Capsid Naked/Enveloped Enveloped
Family Rhabdoviridae
Genus Lyssavirus
Genome Negative-sense, single-strand RNA
Proteome Five structural proteins (nucleoprotein, phosphoprotein, matrix protein, glycoprotein, and RNA-dependent RNA polymerase)
Antigenic Target Surface glycoprotein
Incubation Period 2–3 months but may vary from 1 week to 1 year
Zoonotic Evidence Yes
Host Human, Mammals
Chronology_Time 2000 BC
Regions Affected All continents, except Antarctica, with over 95% of human deaths occurring in the Asia and Africa regions
Susceptible Age Group Ages of 5–14 years
Transmission Route Bitten or scratched by a rabid animal and saliva of infected animals comes into direct contact with human mucosa or fresh skin wounds
Symptoms Fever, headache, excess salivation, muscle spasms, paralysis and mental confusion
Co-infection HIV
Genome Reference Genome Link
Proteome Reference Proteome Link
References Reference 1Reference 2