Poliomyelitis (polio)
Polio or Poliomyelitis, is a disabling and life-threatening disease caused by the poliovirus. The virus spreads from person to person and can infect a person's spinal cord, causing paralysis (can't move parts of the body).
| Detailed Information |
| Disease Name |
Poliomyelitis (polio) |
| Virus Name |
Poliovirus |
| Capsid Symmetry |
Icosahedral capsid |
| Capsid Naked/Enveloped |
Naked |
| Family |
Picornaviridae |
| Genus |
Enterovirus |
| Genome |
Positive-sense single-stranded RNA |
| Proteome |
4 polypeptides, VP1, VP2, VP3 and VP4 |
| Antigenic Target |
Wild strain type 1, 2, and 3; live attenuated (Sabin) strains and the formalin-inactivated (Salk) |
| Incubation Period |
Nonparalytic poliomyelitis is 3 to 6 days and paralytic poliomyelitis is usually 7 to 21 days |
| Zoonotic Evidence |
No |
| Host |
Human |
| Chronology_Time |
1908 |
| Regions Affected |
Worldwide |
| Susceptible Age Group |
Children under 5 years of age |
| Transmission Route |
Fecal-oral contamination |
| Symptoms |
No symptoms usually subject develop paralysis, which can sometimes be fatal. |
| Co-infection |
HIV |
| Genome Reference |
Genome Link |
| Proteome Reference |
Proteome Link |
| References |
Reference 1 |