ViralVacDB | Details of Viral Vaccine

Hepatitis D

Hepatitis D, also known as “delta hepatitis,” is a liver infection caused by the hepatitis D virus (HDV). Hepatitis D only occurs in people who are also infected with the hepatitis B virus. Hepatitis D is spread when blood or other body fluids from a person infected with the virus enters the body of someone who is not infected. Hepatitis D can be an acute, short-term infection or become a long-term, chronic infection. Hepatitis D can cause severe symptoms and serious illness that can lead to life-long liver damage and even death. People can become infected with both hepatitis B and hepatitis D viruses at the same time (known as “coinfection”) or get hepatitis D after first being infected with the hepatitis B virus (known as “superinfection”). There is no vaccine to prevent hepatitis D. However, prevention of hepatitis B with hepatitis B vaccine also protects against future hepatitis D infection.
Detailed Information
Disease Name Hepatitis D
Virus Name Hepatitis D (delta) virus (HDV)
Capsid Symmetry Roughly spherical, with no distinct nucleocapsid structure
Capsid Naked/Enveloped Enveloped
Family Kolmioviridae
Genus Deltavirus
Genome negative sense, single-stranded, closed circular RNA
Proteome One protein with two forms; a 27 kDa large-HDAg (delta-Ag-L), and a small-HDAg of 24 kDa (delta-Ag-S)
Antigenic Target Hepatitis D surface antigen (HDsAg)
Incubation Period Approximately 35 days
Zoonotic Evidence NA
Host Human
Chronology_Time 1977
Regions Affected Worldwide, specially in region Mongolia, the Republic of Moldova, and countries in western and central Africa
Susceptible Age Group All age group
Transmission Route Sexual contact, blood
Symptoms abdominal pain, nausea and fatigue.
Co-infection Hepatitis B , Liver Disease
Genome Reference Genome Link
Proteome Reference Proteome Link
Reference Reference