Hepatitis D
Hepatitis D, also known as “delta hepatitis,” is a liver infection caused
by the hepatitis D virus (HDV). Hepatitis D only occurs in people who are also infected with the
hepatitis B virus. Hepatitis D is spread when blood or other body fluids from a person infected
with the virus enters the body of someone who is not infected. Hepatitis D can be an acute,
short-term infection or become a long-term, chronic infection. Hepatitis D can cause severe
symptoms and serious illness that can lead to life-long liver damage and even death. People can
become infected with both hepatitis B and hepatitis D viruses at the same time (known as
“coinfection”) or get hepatitis D after first being infected with the hepatitis B virus (known
as “superinfection”). There is no vaccine to prevent hepatitis D. However, prevention of
hepatitis B with hepatitis B vaccine also protects against future hepatitis D infection.
| Detailed Information |
| Disease Name |
Hepatitis D |
| Virus Name |
Hepatitis D (delta) virus (HDV) |
| Capsid Symmetry |
Roughly spherical, with no distinct nucleocapsid structure |
| Capsid Naked/Enveloped |
Enveloped |
| Family |
Kolmioviridae |
| Genus |
Deltavirus |
| Genome |
negative sense, single-stranded, closed circular RNA
|
| Proteome |
One protein with two forms; a 27 kDa large-HDAg (delta-Ag-L), and a small-HDAg of 24 kDa (delta-Ag-S) |
| Antigenic Target |
Hepatitis D surface antigen (HDsAg) |
| Incubation Period |
Approximately 35 days |
| Zoonotic Evidence |
NA |
| Host |
Human |
| Chronology_Time |
1977 |
| Regions Affected |
Worldwide, specially in region Mongolia, the Republic of Moldova, and countries in western and central Africa |
| Susceptible Age Group |
All age group |
| Transmission Route |
Sexual contact, blood |
| Symptoms |
abdominal pain, nausea and fatigue. |
| Co-infection |
Hepatitis B , Liver Disease |
| Genome Reference |
Genome
Link |
| Proteome Reference |
Proteome Link |
| Reference |
Reference
|