Hepatitis C
Hepatitis C is an inflammation of the liver caused by the hepatitis C virus.
The virus can cause both acute and chronic hepatitis, ranging in severity from a mild illness to a serious, lifelong illness including liver cirrhosis and cancer.
The hepatitis C virus is a bloodborne virus and most infection occur through exposure to blood from unsafe injection practices, unsafe health care, unscreened blood transfusions, injection drug use and sexual practices that lead to exposure to blood.
Globally, an estimated 58 million people have chronic hepatitis C virus infection, with about 1.5 million new infections occurring per year.
WHO estimated that in 2019, approximately 290 000 people died from hepatitis C, mostly from cirrhosis and hepatocellular carcinoma (primary liver cancer).
Antiviral medicines can cure more than 95% of persons with hepatitis C infection, but access to diagnosis and treatment is low.
There is currently no effective vaccine against hepatitis C.
| Detailed Information |
| Disease Name |
Hepatitis C |
| Virus Name |
Hepatitis A virus (HAV) |
| Capsid Symmetry |
Helical |
| Capsid Naked/Enveloped |
Enveloped |
| Family |
Coronaviridae |
| Genus |
Betacoronavirus |
| Genome |
Single-stranded positive-sense RNA |
| Proteome |
16 non-structural, 9 accessory and 4 structural proteins |
| Antigenic Target |
Spike, membrane, and envelope structural proteins |
| Incubation Period |
1-14 days |
| Zoonotic Evidence |
Yes |
| Host |
Human, bats, pangolin |
| Chronology_Time |
2019 |
| Regions Affected |
Worldwide |
| Susceptible Age Group |
All |
| Transmission Route |
Respiratory, close contact |
| Symptoms |
Fever or chills, Cough, Shortness of breath or difficulty breathing, Fatigue, Muscle or body aches, Headache, New loss of taste or smell, Sore throat, Congestion or runny nose, Nausea or vomiting, Diarrhea |
| Co-infection |
HIV |
| Genome Reference |
Genome Link |
| Proteome Reference |
Proteome Link |
| References |
Reference 1 |