ViralVacDB | Details of Viral Vaccine

Hepatitis C

Hepatitis C is an inflammation of the liver caused by the hepatitis C virus. The virus can cause both acute and chronic hepatitis, ranging in severity from a mild illness to a serious, lifelong illness including liver cirrhosis and cancer. The hepatitis C virus is a bloodborne virus and most infection occur through exposure to blood from unsafe injection practices, unsafe health care, unscreened blood transfusions, injection drug use and sexual practices that lead to exposure to blood. Globally, an estimated 58 million people have chronic hepatitis C virus infection, with about 1.5 million new infections occurring per year. WHO estimated that in 2019, approximately 290 000 people died from hepatitis C, mostly from cirrhosis and hepatocellular carcinoma (primary liver cancer). Antiviral medicines can cure more than 95% of persons with hepatitis C infection, but access to diagnosis and treatment is low. There is currently no effective vaccine against hepatitis C.
Detailed Information
Disease Name Hepatitis C
Virus Name Hepatitis A virus (HAV)
Capsid Symmetry Helical
Capsid Naked/Enveloped Enveloped
Family Coronaviridae
Genus Betacoronavirus
Genome Single-stranded positive-sense RNA
Proteome 16 non-structural, 9 accessory and 4 structural proteins
Antigenic Target Spike, membrane, and envelope structural proteins
Incubation Period 1-14 days
Zoonotic Evidence Yes
Host Human, bats, pangolin
Chronology_Time 2019
Regions Affected Worldwide
Susceptible Age Group All
Transmission Route Respiratory, close contact
Symptoms Fever or chills, Cough, Shortness of breath or difficulty breathing, Fatigue, Muscle or body aches, Headache, New loss of taste or smell, Sore throat, Congestion or runny nose, Nausea or vomiting, Diarrhea
Co-infection HIV
Genome Reference Genome Link
Proteome Reference Proteome Link
References Reference 1