Hepatitis B
Hepatitis B is a vaccine-preventable liver infection caused by the hepatitis B virus (HBV). Hepatitis B is spread when blood, semen, or other body fluids from a person infected with the virus enters the body of someone who is not infected. This can happen through sexual contact; sharing needles, syringes, or other drug-injection equipment; or from mother to baby at birth. Not all people newly infected with HBV have symptoms, but for those that do, symptoms can include fatigue, poor appetite, stomach pain, nausea, and jaundice. For many people, hepatitis B is a short-term illness. For others, it can become a long-term, chronic infection that can lead to serious, even life-threatening health issues like cirrhosis or liver cancer. Risk for chronic infection is related to age at infection: about 90% of infants with hepatitis B go on to develop chronic infection, whereas only 2%–6% of people who get hepatitis B as adults become chronically infected. The best way to prevent hepatitis B is to get vaccinated.
| Detailed Information |
| Disease Name |
Hepatitis B |
| Virus Name |
Hepatitis B virus (HBV) |
| Capsid Symmetry |
Icosahedral |
| Capsid Naked/Enveloped |
Enveloped |
| Family |
Orthohepadnavirus |
| Genus |
Hepadnaviridae |
| Genome |
Double-stranded DNA |
| Proteome |
Large L, middle M, and small S envelope proteins |
| Antigenic Target |
HBeAg,HBsAg |
| Incubation Period |
Average of 90 days with range 60–150 days |
| Zoonotic Evidence |
No |
| Host |
Human, Chimpanzees |
| Chronology_Time |
1965 |
| Regions Affected |
Worldwide |
| Susceptible Age Group |
Adults aged 40-49 years |
| Transmission Route |
Bodily fluid of infected person, Sexual contact, blood |
| Symptoms |
Symptoms are variable and include yellowing of the eyes, abdominal pain and dark urine. Some people, particularly children, don't experience any symptoms. In chronic cases, liver failure, cancer or scarring can occur. |
| Co-infection |
HIV |
| Genome Reference |
Genome Link |
| Proteome Reference |
Proteome Link |
| References |
Reference 1 |