ViralVacDB | Details of Viral Vaccine

Hepatitis B

Hepatitis B is a vaccine-preventable liver infection caused by the hepatitis B virus (HBV). Hepatitis B is spread when blood, semen, or other body fluids from a person infected with the virus enters the body of someone who is not infected. This can happen through sexual contact; sharing needles, syringes, or other drug-injection equipment; or from mother to baby at birth. Not all people newly infected with HBV have symptoms, but for those that do, symptoms can include fatigue, poor appetite, stomach pain, nausea, and jaundice. For many people, hepatitis B is a short-term illness. For others, it can become a long-term, chronic infection that can lead to serious, even life-threatening health issues like cirrhosis or liver cancer. Risk for chronic infection is related to age at infection: about 90% of infants with hepatitis B go on to develop chronic infection, whereas only 2%–6% of people who get hepatitis B as adults become chronically infected. The best way to prevent hepatitis B is to get vaccinated.
Detailed Information
Disease Name Hepatitis B
Virus Name Hepatitis B virus (HBV)
Capsid Symmetry Icosahedral
Capsid Naked/Enveloped Enveloped
Family Orthohepadnavirus
Genus Hepadnaviridae
Genome Double-stranded DNA
Proteome Large L, middle M, and small S envelope proteins
Antigenic Target HBeAg,HBsAg
Incubation Period Average of 90 days with range 60–150 days
Zoonotic Evidence No
Host Human, Chimpanzees
Chronology_Time 1965
Regions Affected Worldwide
Susceptible Age Group Adults aged 40-49 years
Transmission Route Bodily fluid of infected person, Sexual contact, blood
Symptoms Symptoms are variable and include yellowing of the eyes, abdominal pain and dark urine. Some people, particularly children, don't experience any symptoms. In chronic cases, liver failure, cancer or scarring can occur.
Co-infection HIV
Genome Reference Genome Link
Proteome Reference Proteome Link
References Reference 1