ViralVacDB | Details of Viral Vaccine

Hepatitis A

Hepatitis A is a vaccine-preventable liver infection caused by the hepatitis A virus (HAV). HAV is found in the stool and blood of people who are infected. Hepatitis A is very contagious. It is spread when someone unknowingly ingests the virus — even in microscopic amounts — through close personal contact with an infected person or through eating contaminated food or drink. Symptoms of hepatitis A can last up to 2 months and include fatigue, nausea, stomach pain, and jaundice. Most people with hepatitis A do not have long-lasting illness. The best way to prevent hepatitis A is to get vaccinated.
Detailed Information
Disease Name Hepatitis A
Virus Name Hepatitis A virus (HAV)
Capsid Symmetry Icosahedral
Capsid Naked/Enveloped Naked
Family Picornaviridae
Genus Hepatovirus
Genome Single-stranded positive-sense RNA
Proteome 16 non-structural, 9 accessory and 4 structural proteins
Antigenic Target HAV capsid, Genotype I, II, III
Incubation Period Approximately 28 days (range 15 to 50 days)
Zoonotic Evidence No
Host Human
Chronology_Time 1979
Regions Affected Worldwide
Susceptible Age Group Adults age 20 through 39 years
Transmission Route Fecal-oral
Symptoms Fatigue, nausea,jaundice, abdominal pain, loss of appetite and low-grade fever
Co-infection HIV
Genome Reference Genome Link
Proteome Reference Proteome Link
References Reference 1