ViralVacDB | Details of Viral Vaccine

Lassa Fever

Lassa fever is an acute viral haemorrhagic illness caused by Lassa virus, a member of the arenavirus family of viruses.Lassa fever causes around 5,000 deaths per year.The disease is endemic to a number of West African countries.
Detailed Information
Disease Name Lassa Fever
Virus Name Lassa virus
Capsid Symmetry Complex
Capsid Naked/Enveloped Enveloped
Family Arenaviridae
Genus Arenavirus
Genome Single-stranded negative-sense RNA
Proteome L segment of about 7.3 kb and an S segment of 3.5 kb
Antigenic Target Glycoprotein (GP) spike
Incubation Period 6–21 days
Zoonotic Evidence Yes
Host Human, rats
Chronology_Time First identified in 1969 in Jos, Nigeria
Regions Affected Benin Republic in 2014, Ghana in 2011, Guinea, Liberia, and Mali in 2009, Sierra Leone, and Nigeria
Susceptible Age Group All
Transmission Route Zoonosis, fomites
Symptoms fever, general weakness, and malaise after a few days, headache, sore throat, muscle pain, chest pain, nausea, vomiting, diarrhoea, cough, and abdominal pain may follow
Co-infection HIV
Genome Reference Genome Link
Proteome Reference Proteome Link
References Reference 1