ViralVacDB | Details of Viral Vaccine

Dengue Fever

Dengue is a viral infection transmitted to humans through the bite of infected mosquitoes. The primary vectors that transmit the disease are Aedes aegypti mosquitoes and, to a lesser extent, Ae. albopictus.The virus responsible for causing dengue, is called dengue virus (DENV). There are four DENV serotypes and it is possible to be infected four times.
Detailed Information
Disease Name Dengue Fever
Virus Name Dengue virus (DENV)
Capsid Symmetry Icosahedral
Capsid Naked/Enveloped Enveloped
Family Flaviviridae
Genus Flavivirus
Genome Single-stranded positive-sense RNA
Proteome Three structural proteins (C, prM and E) and seven nonstructural proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B and NS5)
Antigenic Target CYD-TDV
Incubation Period 4–10 days
Zoonotic Evidence Yes
Host Human, mosquitoes
Chronology_Time 1943
Regions Affected Americas, Africa, the Middle East, Asia, and the Pacific Islands
Susceptible Age Group All
Transmission Route Zoonosis, arthropod bite(Aedes mosquitoes)
Symptoms high fever, headache, rash and muscle and joint pain
Co-infection HIV
Genome Reference Genome Link
Proteome Reference Proteome Link
References Reference 1