ViralVacDB | Details of Viral Vaccine

Crimean Cargo Hemorrhagic fever

Crimean-Congo hemorrhagic fever (CCHF) is caused by infection with a tick-borne virus (Nairovirus) in the family Bunyaviridae. The disease was first characterized in the Crimea in 1944 and given the name Crimean hemorrhagic fever.
Detailed Information
Disease Name Crimean Cargo Hemorrhagic fever
Virus Name Crimean-Congo hemorrhagic fever virus
Capsid Symmetry Helical
Capsid Naked/Enveloped Enveloped
Family Bunyaviridae
Genus Nairovirus
Genome Single-stranded negative-sense RNA
Proteome The genomic RNA segments are named according to their relative size, with the large (L) segment encoding the viral polymerase, the medium (M) segment encoding envelope-associated GPs (Gn and Gc) and several non-structural proteins, and the small (S) segment, through ambisense coding strategy, encoding the nucleoprotein (NP) and non-structural protein (NSs)
Antigenic Target CCHFV strain Baghdad-12 nucleocapsid protein (N), Gn-Gc glycoprotein
Incubation Period 5 to 6 days, with a maximum of 13 days
Zoonotic Evidence Yes
Host Human, vertebrates, ticks
Chronology_Time 1944
Regions Affected Western and Central Asia, the Middle East, South-Eastern Europe, and Africa
Susceptible Age Group All
Transmission Route Zoonosis, arthropod bite
Symptoms Headache, high fever, back pain, joint pain, stomach pain, and vomiting with Red eyes, a flushed face, a red throat, and petechiae (red spots) on the palate are common
Co-infection HIV
Genome Reference Genome Link
Proteome Reference Proteome Link
References Reference 1Reference 2