Astrovirus Infection
Astrovirus infection in mammals presents clinically as gastroenteritis. Disease has been most closely studied in humans and, in volunteer studies, astrovirus-infected individuals develop diarrhea, the most prominent symptom, as well as vomiting, nausea, anxiety, headache, malaise, abdominal discomfort, and fever.
| Detailed Information |
| Disease Name |
Astrovirus infection |
| Virus Name |
Astroviruses |
| Capsid Symmetry |
Icosahedral |
| Capsid Naked/Enveloped |
Naked |
| Family |
Astroviridae |
| Genus |
Mamastrovirus |
| Genome |
Single-stranded positive-sense RNA |
| Proteome |
Three major structural proteins, ORF1a and ORF1b at the 5′ end encoding the nonstructural proteins and ORF2 at the 3′ end encoding the structural proteins |
| Antigenic Target |
Capsid region (ORF2) |
| Incubation Period |
3 to 4 days |
| Zoonotic Evidence |
Yes |
| Host |
Human |
| Chronology_Time |
1975 |
| Regions Affected |
US, Vietnam, China, Korea, Japan,Egypt, Italy,Spain and France |
| Susceptible Age Group |
Young children |
| Transmission Route |
Water and food and disinfection of contaminated fomites |
| Symptoms |
Diarrhea, fever, vomiting, abdominal pain, headache, and mild dehydration |
| Co-infection |
significantly associated with diarrheal illness in immunocompromised AIDS patients , solid organ transplant recipients , and bone marrow transplant recipients |
| Genome Reference |
Genome Link |
| Proteome Reference |
Proteome Link |
| References |
Reference 1 |