Smallpox
Smallpox is an infectious disease caused by the variola virus. It is characterized by fever, a general feeling of ill health (malaise), headaches and back pain. These initial symptoms are followed by a rash and small, raised bumps or lesions (pocks) within two or three days. Smallpox was a highly contagious disease, but was declared eradicated in 1980.
| Detailed Information
|
| Disease Name |
Smallpox |
| Virus Name |
variola virus |
| Capsid Symmetry |
Complex |
| Capsid Naked/Enveloped |
Complex coats |
| Family |
Poxviridae |
| Genus |
Orthopoxvirus |
| Genome |
Double-stranded DNA genomes |
| Proteome |
Approximately 200 proteins, over which 80
of these proteins are located in the terminal regions of the
genome |
| Antigenic Target |
Lister or the New York City Board of
Health strain |
| Incubation Period |
0 to 14 days (range 7 to 19 days) |
| Zoonotic Evidence |
No |
| Host |
Human |
| Chronology_Time |
Timeline |
| Regions Affected |
Smallpox existed for thousands of years until the World Health Organization declared it extinct in May of 1980. The last known case of smallpox occurred in Somalia in 1977 |
| Susceptible Age Group |
Children and young people aged 0-19 years |
| Transmission Route |
Aerosol |
| Symptoms |
Pus-filled blisters to develop all over
the body |
| Co-infection |
Monkeypox |
| Genome Reference |
Genome Link |
| Proteome Reference |
Proteome Link |
| Reference |
Reference
|