Browse by Vaccine Status

This page shows data for Preclinical Vaccine Status.
Total Entries Retrieved: 44
IDVaccine NameDisease NameDisease ClassificationVirus NameNucleic Acid ContentVaccine TypeVaccine StatusManufacturerYear of ManufacturingManufacturing CountryAgeDosageAdministration RouteAdjuvantTarget StrainDescriptionApproving OrganisationCollaborating OrganisationOther CountriesTrade NamePMIDClinical Trial IDReference LinkAdditional Links
10379 Bulgarian vaccine Crimean-Congo haemorrhagic fever Hemorrhagic Nairovirus negative-sense, single-stranded RNA Inactivated Preclinical NA 1974 Union of Soviet Socialist Republics 16 years and above NA Subcutaneous Aluminum (aluminium hydroxide) NA Prepared from brain tissue of CCHFV infected newborn mice NA NA NA Zabdeno, Mvabea 32461819 NA https://www.liebertpub.com/doi/10.1089/biores.2019.0057 https://www.ema.europa.eu/en/documents/product-information/zabdeno-epar-product-information_en.pdf
10380 Trivalent combination vaccine Norovirus Infection Gastrointestinal Norovirus positive-sense, single-stranded RNA Virus like particle Preclinical University of Tampere 2013 Finland NA NA Intramuscular, Intranasal NA GII-4, GI-3 VLP, rVP6 Baculovirus expressed noroviruses VLPs NA NA NA NA 23922988 NA https://www.cdc.gov/norovirus/downloads/global-burden-report.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724941/
10381 Delta gD-2 Genital Herpes Cutaneous Herpes simplex virus double stranded DNA Subunit vaccine Preclinical X-Vax Technology Inc. NA USA NA NA Intramuscular NA Herpes simplex virus 2 glycoprotein D (gD-2) NA NA NA NA NA NA NA https://www.precisionvaccinations.com/vaccines/herpes-vaccine-candidates https://www.frontiersin.org/articles/10.3389/fmicb.2021.798927/full
10382 EXD-12 Genital Herpes Cutaneous Herpes simplex virus double stranded DNA Live-attenuated Preclinical Excell Biotech 2018 USA 14 - 49 years NA NA NA Herpes simplex virus 2 glycoprotein D (gD-2) NA NA NA NA NA NA NA https://www.precisionvaccinations.com/vaccines/herpes-vaccine-candidates NA
10383 NanoVax Genital Herpes Cutaneous Herpes simplex virus double stranded DNA Subunit vaccine Preclinical BlueWillow Biologics NA USA NA NA Intranasal NA Herpes simplex virus 2 glycoprotein D (gD-2) NA NA NA NA NA NA NA https://www.precisionvaccinations.com/vaccines/herpes-vaccine-candidates NA
10384 RVx201 Genital Herpes Cutaneous Herpes simplex virus double stranded DNA Live-attenuated Preclinical Rational Vaccines Inc. 2021 UK NA NA NA NA HSV-2 infected cell protein NA NA NA NA NA NA NA https://www.precisionvaccinations.com/vaccines/herpes-vaccine-candidates NA
10385 DeltaC-CHIKV Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Live-attenuated Preclinical NA NA NA NA Single dose Subcutaneous NA Capsid deletion NA NA NA NA NA 31921059 NA https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930866/ NA
10386 Stop CHIKV SuperStop CHIKV Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Live-attenuated Preclinical NA NA NA NA Single dose Footpad injection NA NA NA NA NA NA NA 31921059 NA https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930866/ NA
10387 DRDE-06 Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Live-attenuated Preclinical NA NA NA NA 3 doses NA NA NA Formalin inactivated produced in vero cells NA NA NA NA NA NA https://academic.oup.com/jid/article/214/suppl_5/S488/2632628 NA
10388 CHIK-E1/E2 Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Subunit vaccine Preclinical NA NA NA NA 3 doses NA NA E1/E2 Recombinant E1/E2 produced in E. coli NA NA NA NA NA NA https://academic.oup.com/jid/article/214/suppl_5/S488/2632628 NA
10389 CHIK-E2 Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Subunit vaccine Preclinical NA NA NA NA 2 doses NA NA E1 Recombinant E2 produced in E. coli NA NA NA NA NA NA https://academic.oup.com/jid/article/214/suppl_5/S488/2632628 NA
10390 VLP-CHIKV-S27 Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Virus like particle Preclinical NA NA NA NA 2 doses NA NA CHIKV proteins Baculovirus-vectored CHIKV VLPs formulated with adjuvant NA NA NA NA NA NA https://academic.oup.com/jid/article/214/suppl_5/S488/2632628 NA
10391 Chimeric alphavirus Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Live-attenuated Preclinical NA NA NA NA Single dose NA NA CHIKV structural proteins Recombinant alphavirus (EEEV, VEEV, SINV) with CHIKV structural proteins NA NA NA NA NA NA https://academic.oup.com/jid/article/214/suppl_5/S488/2632628 NA
10392 CHIKV/IRES Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Live-attenuated Preclinical NA NA NA NA Single dose NA NA CHIKV structural proteins NA NA NA NA NA NA NA https://academic.oup.com/jid/article/214/suppl_5/S488/2632628 NA
10393 VSV-CHIKV Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Live-attenuated Preclinical NA NA NA NA Single dose NA NA CHIKV structural proteins NA NA NA NA NA NA NA https://academic.oup.com/jid/article/214/suppl_5/S488/2632628 NA
10394 CAdVax-CHIK Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Recombinant viral vector Preclinical GenPhar Inc. NA NA NA Single dose NA NA CHIKV structural proteins Produced in HEK293 packaging cell line NA NA NA NA NA NA https://academic.oup.com/jid/article/214/suppl_5/S488/2632628 https://www.sciencedirect.com/science/article/pii/S0264410X16300731
10395 MVA-CHIKV Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Recombinant viral vector Preclinical NA NA NA NA Single dose NA NA CHIKV structural proteins NA NA NA NA NA NA NA https://academic.oup.com/jid/article/214/suppl_5/S488/2632628 NA
10396 pMCE321 Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA DNA based vaccine Preclinical NA NA NA NA NA Intramuscular NA Sequence of E3, E2, and E1 genes under a CMV promoter NA NA NA NA NA NA NA https://academic.oup.com/jid/article/214/suppl_5/S488/2632628 NA
10397 iDNA Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA DNA based vaccine Preclinical NA NA NA NA NA Intramuscular NA CHIKV strain 181/25 NA NA NA NA NA NA NA https://academic.oup.com/jid/article/214/suppl_5/S488/2632628 NA
10398 DREP-Env Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA DNA based vaccine Preclinical NA NA NA NA NA Intradermal NA CHIKV replicon (nsP1 to nsP4) and CHIKV envelope proteins (E1, E2, and E3) NA NA NA NA NA NA NA https://academic.oup.com/jid/article/214/suppl_5/S488/2632628 NA
10399 LR-E2-E79 K Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Live-attenuated Preclinical NA NA NA NA NA NA NA Clinical strain LR attenuated by mutations in heparin sulfate binding domains NA NA NA NA NA NA NA https://link.springer.com/chapter/10.1007/82_2019_175 NA
10400 CHIKV TM17-2 Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Live-attenuated Preclinical NA NA NA NA NA NA NA Clinical strain attenuated by mutations in E2 transmembrane domain NA NA NA NA NA NA NA https://link.springer.com/chapter/10.1007/82_2019_175 NA
10401 CHIKV/IRES Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Live-attenuated Preclinical NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA https://link.springer.com/chapter/10.1007/82_2019_175 NA
10402 VSVdelG-CHIKV Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Recombinant viral vector Preclinical NA NA NA NA NA NA NA Glycoprotein-deficient VSV encoding CHIKV structural proteins NA NA NA NA NA NA NA https://link.springer.com/chapter/10.1007/82_2019_175 NA
10403 VEE/CHIKV Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Recombinant viral vector Preclinical NA NA NA NA NA NA NA Chimera consisting of VEEV nsP and CHIKV structural proteins NA NA NA NA VEE/IRES-C/CHIKV NA NA https://link.springer.com/chapter/10.1007/82_2019_175 NA
10404 EILV/CHIKV Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Recombinant viral vector Preclinical NA NA NA NA NA NA NA Eilat virus nonstructural and CHIKV structural proteins NA NA NA NA NA NA NA https://link.springer.com/chapter/10.1007/82_2019_175 NA
10405 CAdVax-CHIK Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Recombinant viral vector Preclinical NA NA NA NA NA NA NA Replication-deficient Ad5 encoding CHIKV structural proteins NA NA NA NA NA NA NA https://link.springer.com/chapter/10.1007/82_2019_175 NA
10406 MVA-6KE1E3E2 Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Recombinant viral vector Preclinical NA NA NA NA NA NA NA MVA encoding CHIKV structural proteins NA NA NA NA NA NA NA https://link.springer.com/chapter/10.1007/82_2019_175 NA
10407 MVA-E2E3 Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Recombinant viral vector Preclinical NA NA NA NA NA NA NA CHIKV envelope protein (E2, E3) NA NA NA NA NA NA NA https://link.springer.com/chapter/10.1007/82_2019_175 NA
10408 MVA-CHIKV Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Recombinant viral vector Preclinical NA NA NA NA NA Intraperitoneal NA CHIKV structural proteins (C, E3, E2, 6K, E1) into MVA NA NA NA NA NA NA NA https://link.springer.com/chapter/10.1007/82_2019_175 NA
10409 UV-CHIKV Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Inactivated Preclinical NA NA NA NA NA NA NA CHIKV proteins Inactivated by UV-irradiation NA NA NA NA NA NA https://link.springer.com/chapter/10.1007/82_2019_175 NA
10410 BEI-CHIKV Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Inactivated Preclinical NA NA NA NA NA NA NA CHIKV proteins Inactivated by binary ethyleneimine NA NA NA NA NA NA https://link.springer.com/chapter/10.1007/82_2019_175 NA
10411 Formalin-inactivated CHIKV Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Inactivated Preclinical NA NA NA NA NA NA NA CHIKV proteins Inactivated by formalin NA NA NA NA NA NA https://link.springer.com/chapter/10.1007/82_2019_175 NA
10412 Tween/Ether-CHIKV Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Inactivated Preclinical NA NA NA NA NA NA NA CHIKV proteins Inactivated by Tween 80 and ether NA NA NA NA NA NA https://link.springer.com/chapter/10.1007/82_2019_175 NA
10413 rCHIKVE1/E2 Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Subunit vaccine Preclinical NA NA NA NA NA NA NA Recombinant E1 and E2 proteins NA NA NA NA NA NA NA https://link.springer.com/chapter/10.1007/82_2019_175 NA
10414 rE2p Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA Subunit vaccine Preclinical NA NA NA NA NA NA NA Recombinant E2 protein NA NA NA NA NA NA NA https://link.springer.com/chapter/10.1007/82_2019_175 NA
10415 p181/25-7 Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA DNA based vaccine Preclinical NA NA NA NA NA NA NA CHIKV strain 181/25 NA NA NA NA NA NA NA https://link.springer.com/chapter/10.1007/82_2019_175 NA
10416 CVM1-IgG Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA DNA based vaccine Preclinical NA NA NA NA NA NA NA E2-reactive monoclonal antibody NA NA NA NA NA NA NA https://link.springer.com/chapter/10.1007/82_2019_175 NA
10417 pVax1-MCE321 Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA DNA based vaccine Preclinical NA NA NA NA NA NA NA CHIKV envelope proteins (E1, E2, and E3) NA NA NA NA NA NA NA https://link.springer.com/chapter/10.1007/82_2019_175 NA
10418 DREP-Env Chikungunya fever Exanthous Chikungunya virus positive-sense, single-stranded RNA DNA based vaccine Preclinical NA NA NA NA NA Intradermal NA DNA replicon encoding nsP and E1, E2, E3 NA NA NA NA NA NA NA https://link.springer.com/chapter/10.1007/82_2019_175 NA
10419 GII.4 P particles Norovirus Infection Gastrointestinal Norovirus positive-sense, single-stranded RNA Virus like particle Preclinical Cincinnati Children’s Hospital Medical Center NA USA NA NA Intranasal NA P particles derived from HuNoV VP1 NA NA Southern Medical University, Virginia Polytechnic Institute and State University NA NA NA NA https://www.mdpi.com/2076-393X/9/7/732/htm https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851174/
10420 Plant-expressed GII.4 VLPs Norovirus Infection Gastrointestinal Norovirus positive-sense, single-stranded RNA Virus like particle Preclinical Arizona State University NA USA NA NA Intranasal NA HuNoV GII.4 VLP NA NA NA NA NA NA NA https://www.mdpi.com/2076-393X/9/7/732/htm https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054422/
10421 GII.4 VLPs combined with EV71 VLPs Norovirus Infection Gastrointestinal Norovirus positive-sense, single-stranded RNA Virus like particle Preclinical Institut Pasteur of Shanghai NA China NA NA Intramuscular NA HuNoV GII.4 and enterovirus 71 VLPs NA NA NA NA NA NA NA https://www.mdpi.com/2076-393X/9/7/732/htm NA
10422 Norovirus P particle and combination vaccines Norovirus Infection Gastrointestinal Norovirus positive-sense, single-stranded RNA Subunit vaccine Preclinical Cincinnati Children’s Hospital Medical Center NA USA NA NA Intranasal Chitosan, MPL and TNC buffer P domains representing different GI and GII strains Baculovirus vector in E.coli or yeast system NA NA NA NA NA NA https://www.cdc.gov/norovirus/downloads/global-burden-report.pdf NA