|
10313
|
Convidecia
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Non-replicating viral vector
|
Phase 3
|
CanSino Biologics Inc.
|
2020
|
China
|
18 years and above
|
Single dose
|
Intramuscular
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
PakVac, Recombinant novel coronavirus vaccine (Adenovirus type 5 vector)
|
NA
|
NCT04526990
|
https://clinicaltrials.gov/show/NCT04526990
|
NA
|
|
10314
|
Nanocovax
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Protein subunit
|
Phase 3
|
Nanogen Pharmaceutical Biotechnology JSC
|
2021
|
Vietnam
|
18 years and above
|
2 doses 28 days apart
|
Intramuscular
|
Aluminum
|
Spike protein of SARS-CoV-2 virus
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
NCT04922788
|
https://clinicaltrials.gov/show/NCT04922788
|
NA
|
|
10315
|
Omicron COVID-19 Vaccine (Vero Cell), Inactivated
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Inactivated
|
Phase 3
|
China National Biotec Group Company Limited
|
2020
|
China
|
NA
|
NA
|
Intramuscular
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
http://www.chictr.org.cn/showproj.aspx?proj=62581
|
https://covid-19pharmacovigilance.paho.org/sinopharmbibp
|
|
10316
|
Inactivated SARS-CoV-2 vaccine (Vero cell)
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Inactivated
|
Phase 3
|
Laboratorio Elea Phoenix S.A.
|
2020
|
Argentina
|
18 - 85 years
|
2 doses 21 days apart
|
Intramuscular
|
Aluminum (aluminium hydroxide)
|
SARS-CoV-2 HB02 strain
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
NCT04560881
|
https://clinicaltrials.gov/show/NCT04560881
|
NA
|
|
10317
|
Inactivated SARS-CoV-2 vaccine (Vero cell)
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Inactivated
|
Phase 3
|
Health Institutes of Turkey
|
2020
|
Turkey
|
18 - 59 years
|
2 doses 14 days apart
|
Intramuscular
|
NA
|
SARS-CoV-2 virus antigenic protein
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
NCT04582344
|
https://clinicaltrials.gov/show/NCT04582344
|
NA
|
|
10318
|
Covidful
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Live-attenuated
|
Phase 3
|
Chinese Academy of Medical Sciences
|
2021
|
China
|
18 years and above
|
2 doses 2 weeks apart
|
Intramuscular
|
NA
|
NA
|
NA
|
NA
|
Institute of Medical Biology
|
Brazil, Malaysia
|
IMBCAMS COVID-19 vaccine
|
NA
|
NCT04659239
|
https://clinicaltrials.gov/show/NCT04659239
|
https://clinicaltrials.gov/ct2/show/NCT05164731
|
|
10319
|
Recombinant SARS-CoV-2 vaccine (Sf9 Cell)
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Protein subunit
|
Phase 3
|
West China Hospital, Sichuan University
|
2021
|
China
|
18 years and above
|
3 doses on day 0, 21 and 42
|
Intramuscular
|
Aluminum (aluminium hydroxide)
|
SARS-CoV-2 receptor-binding domain from spike protein
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
NCT04887207
|
https://clinicaltrials.gov/show/NCT04887207
|
https://clinicaltrials.gov/ct2/show/NCT04530656
|
|
10320
|
CVAC
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
RNA based vaccine
|
Phase 3
|
CureVac AG
|
2021
|
Belgium
|
18 years and above
|
2 doses 28 days apart
|
Intramuscular
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
NCT04860258
|
https://clinicaltrials.gov/ct2/show/NCT04860258?term=NCT04860258&draw=2&rank=1
|
NA
|
|
10321
|
WIBP-CorV
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Inactivated
|
Phase 3
|
Sinopharm, Wuhan Institute of Biological Products
|
2021
|
China
|
18 years and above
|
2 doses 21 days apart
|
Intramuscular
|
NA
|
SARS-CoV-2 whole virus
|
NA
|
NA
|
G42 Healthcare company, Abu Dhabi Health Services Company, Wuhan Institute of Biological Products Co. Ltd, Beijing Institute of Biological Products Co Ltd.
|
China, UAE
|
Zhongkangkewei
|
33816047
|
NCT04510207
|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003899/
|
https://clinicaltrials.gov/ct2/show/NCT04510207
|
|
10322
|
Convidecia
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Recombinant viral vector
|
Phase 3
|
CanSino Biologics Inc.
|
NA
|
China
|
NA
|
Single dose
|
Intramuscular
|
NA
|
NA
|
NA
|
NA
|
Beijing Institute of Biotechnology
|
NA
|
Adenovirus type 5 vector
|
33816047
|
NA
|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003899/
|
NA
|
|
10323
|
BNT162b1
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
RNA based vaccine
|
Phase 3
|
BioNTech SE, Pfizer Inc.
|
NA
|
NA
|
NA
|
2 doses 28 days apart
|
Intramuscular
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
33816047
|
NCT04368728
|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003899/
|
https://clinicaltrials.gov/ct2/show/NCT04368728
|
|
10324
|
INO-4800
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
RNA based vaccine
|
Phase 3
|
Inovio Pharmaceuticals
|
2021
|
USA
|
18 years and above
|
2 doses 28 days apart
|
Intradermal
|
NA
|
Spike protein of SARS-CoV-2 virus
|
NA
|
US FDA
|
NA
|
NA
|
NA
|
32328406
|
NA
|
https://pubmed.ncbi.nlm.nih.gov/32328406/
|
https://ir.inovio.com/news-releases/news-releases-details/2021/INOVIO-Further-Expands-INNOVATE-Phase-3-Trial-for-COVID-19-DNA-Vaccine-Candidate-INO-4800-With-Regulatory-Authorization-from-India/default.aspx
|
|
10325
|
INO-4800
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
DNA based vaccine
|
Phase 3
|
Inovio Pharmaceuticals
|
2021
|
USA
|
18 years and above
|
2 doses 28 days apart
|
Intradermal
|
NA
|
Spike protein of SARS-CoV-2 virus
|
NA
|
US FDA
|
NA
|
NA
|
NA
|
33816047
|
NA
|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003899/
|
https://www.isrctn.com/ISRCTN15779782
|
|
10326
|
Covovax (Nuvaxovid)
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Protein subunit
|
Phase 3
|
Novavax Inc.
|
NA
|
NA
|
NA
|
2 doses 21 days apart
|
Intramuscular
|
Matrix-M1
|
Spike protein of SARS-CoV-2 virus
|
NA
|
NA
|
NA
|
NA
|
TAK-019, SARS-CoV-2 rS
|
33816047
|
NA
|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003899/
|
NA
|
|
10327
|
Covaxin
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Inactivated
|
Phase 3
|
Bharat Biotech International Limited
|
NA
|
India
|
NA
|
2 doses 14 days apart
|
Intramuscular
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
BBV152
|
33816047
|
NA
|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003899/
|
NA
|
|
10328
|
BriLife
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Recombinant viral vector
|
Phase 3
|
Israel Institute for Biological Research
|
2021
|
Israel
|
18 - 55 years
|
NA
|
Intramuscular
|
NA
|
Spike protein of SARS-CoV-2 virus
|
NA
|
NA
|
Weizmann Institute of Science
|
NA
|
IIBR-100
|
33937326
|
NCT04990466
|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082173/
|
NA
|
|
10329
|
GRAd-COV2
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Recombinant viral vector
|
Phase 3
|
ReiThera Srl
|
2021
|
Italy
|
18 years and above
|
2 doses 21 days apart
|
Intramuscular
|
Replication defective Simian Adenovirus (GRAd) encoding S
|
Spike protein of SARS-CoV-2 virus
|
NA
|
NA
|
NA
|
NA
|
NA
|
33816047
|
NCT04791423
|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003899/
|
NA
|
|
10330
|
JCOVDEN
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Non-replicating viral vector
|
Phase 3
|
Janssen Vaccines & Prevention B.V.
|
NA
|
NA
|
18 years and above
|
NA
|
Intramuscular
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
Ad26.COV2.S, JNJ-78436735,Ad26COVS1, VAC31518,COVID-19 Vaccine Janssen,Johnson & Johnson COVID‑19 vaccine
|
33937326
|
NA
|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082173/
|
NA
|
|
10331
|
CVAC
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
RNA based vaccine
|
Phase 3
|
CureVac AG
|
2021
|
Belgium
|
18 years and above
|
2 doses 28 days apart
|
Intramuscular
|
NA
|
SARS-CoV-2 receptor-binding domain from spike protein
|
mRNA based vaccine
|
NA
|
NA
|
NA
|
CVnCoV
|
33816047
|
NCT04860258
|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003899/
|
NA
|
|
10332
|
QazVac
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Inactivated
|
Phase 3
|
Research Institute for Biological Safety Problems
|
2021
|
Kazakhstan
|
18 years and above
|
2 doses 28 days apart
|
Intramuscular
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
QazCovid-in
|
33816047
|
NCT04691908
|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003899/
|
NA
|
|
10333
|
AG0301-COVID19
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
DNA based vaccine
|
Phase 3
|
AnGes Inc.
|
2021
|
Japan
|
18 years and above
|
2 doses 14 days apart
|
Intramuscular
|
NA
|
Spike protein of SARS-CoV-2 virus
|
NA
|
NA
|
Japan Agency for Medical Research and Development
|
NA
|
NA
|
33816047
|
NCT04655625
|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003899/
|
NA
|
|
10334
|
AWcorna
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
RNA based vaccine
|
Phase 3
|
Academy of Military Sciences, Walvax Biotechnology Co. Ltd.
|
2021
|
China
|
18 years and above
|
2 doses 28 days apart
|
Intramuscular
|
NA
|
Spike protein of SARS-CoV-2 virus
|
mRNA based vaccine
|
NA
|
NA
|
NA
|
Walvax COVID-19 vaccine, ARCoV
|
NA
|
NCT04847102
|
https://delta.larvol.com/products/?ProductId=4355caae-8746-469c-ab52-0b40ddfde811&Index=0
|
NA
|
|
10335
|
ARCT-154
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
RNA based vaccine
|
Phase 3
|
Vinbiocare Biotechnology Joint Stock Company
|
2021
|
Vietnam
|
18 years and above
|
2 doses 28 days apart
|
Intramuscular
|
NA
|
Spike protein of SARS-CoV-2 virus
|
NA
|
NA
|
Arcturus Therapeutics Inc.
|
NA
|
VBC-COV19-154
|
NA
|
NCT05012943
|
https://clinicaltrials.gov/ct2/show/NCT05012943
|
NA
|
|
10336
|
Covishield
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Recombinant viral vector
|
Phase 3
|
AstraZeneca plc
|
2021
|
Brazil
|
18 years and above
|
2 doses 28 days apart
|
Intramuscular
|
NA
|
SARS-CoV-2 variant strain B.1.351
|
NA
|
NA
|
NA
|
Brazil, UK, South Africa
|
AZD1222,ChAdOx1 nCoV-19, ChAdOx1-S, COVID-19 Vaccine AstraZeneca, AstraZeneca COVID-19 Vaccine, AZD2816,Vaxzevria
|
NA
|
NCT04973449
|
https://clinicaltrials.gov/ct2/show/NCT04973449
|
NA
|
|
10337
|
SCB-2019
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Protein subunit
|
Phase 3
|
Clover Biopharmaceuticals
|
2021
|
Australia
|
18 years and above
|
2 doses 21 days apart
|
Intramuscular
|
AS03, CpG 1018, alum
|
Spike protein of SARS-CoV-2 virus
|
NA
|
NA
|
GlaxoSmithKline, Dynavax
|
NA
|
NA
|
33816047
|
NCT04672395
|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003899/
|
NA
|
|
10338
|
Covifenz
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Virus like particle
|
Phase 3
|
Medicago Inc
|
NA
|
NA
|
NA
|
2 doses 21 days apart
|
Intramuscular
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
CoVLP
|
33816047
|
NA
|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003899/
|
NA
|
|
10339
|
UB-612
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Protein subunit
|
Phase 3
|
Vaxxinity
|
2021
|
USA
|
18 years and above
|
2 doses 28 days apart
|
Intramuscular
|
NA
|
SARS-CoV-2 receptor-binding domain from spike protein
|
NA
|
NA
|
NA
|
NA
|
NA
|
33816047
|
NA
|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003899/
|
NA
|
|
10340
|
Recombinant SARS-CoV-2 vaccine (Sf9 Cell)
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Protein subunit
|
Phase 3
|
West China Hospital, Sichuan University
|
2021
|
China
|
18 years and above
|
2 doses 28 days apart
|
Intramuscular
|
NA
|
SARS-CoV-2 receptor-binding domain from spike protein
|
NA
|
NA
|
NA
|
NA
|
NA
|
33816047
|
NA
|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003899/
|
NA
|
|
10341
|
AZD1222 (ChAdOx1)
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Virus like particle
|
Phase 3
|
Janssen Pharmaceutical
|
NA
|
NA
|
18 - 55 years
|
2 doses 28 days apart
|
Intramuscular
|
NA
|
Spike protein of SARS-CoV-2 virus
|
NA
|
NA
|
NA
|
NA
|
NA
|
33402220
|
NA
|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785400/
|
NA
|
|
10342
|
WIBP-CorV
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Inactivated
|
Phase 3
|
Wuhan Institute of Biological Products
|
NA
|
NA
|
18 - 59 years
|
Single dose
|
Intramuscular
|
NA
|
Inactivated SARS-CoV-2 virus
|
NA
|
NA
|
NA
|
NA
|
NVX-CoV2373
|
33402220
|
NA
|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785400/
|
NA
|
|
10343
|
Vidprevtyn
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Protein subunit
|
Phase 3
|
Sanofi Pasteur, GlaxoSmithKline
|
2021
|
USA
|
18 years and above
|
2 doses 14 days apart
|
Intramuscular
|
NA
|
SARS-CoV-2 protein
|
NA
|
NA
|
GlaxoSmithKline
|
USA, Colombia, Honduras, Japan, Kenya
|
VAT00002, VAT00008
|
NA
|
NCT04904549
|
https://clinicaltrials.gov/ct2/show/NCT04904549
|
https://www.sanofi.com/en/our-covid-19-vaccine-candidates/phase-3-clinical-trial-for-COVID19-recombinant-protein-vaccine-candidate
|
|
10344
|
CVAC
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
RNA based vaccine
|
Phase 3
|
CureVac AG
|
NA
|
Germany
|
NA
|
NA
|
Intramuscular
|
NA
|
NA
|
mRNA based vaccine
|
NA
|
NA
|
Germany, Cuba, Peru
|
CVnCoV
|
NA
|
NCT04674189
|
https://extranet.who.int/pqweb/sites/default/files/documents/Status_of_COVID-19_Vaccines_within_WHO_EUL-PQ_evaluation_process-16June2021_Final.pdf
|
https://clinicaltrials.gov/ct2/show/NCT04674189
|
|
10345
|
CoV2 preS dTM-AS03 vaccine
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Protein subunit
|
Phase 3
|
Sanofi Pasteur
|
NA
|
NA
|
NA
|
NA
|
Intramuscular
|
NA
|
NA
|
Recombinant
|
EMA
|
NA
|
NA
|
NA
|
NA
|
NCT04904549
|
https://extranet.who.int/pqweb/sites/default/files/documents/Status_of_COVID-19_Vaccines_within_WHO_EUL-PQ_evaluation_process-16June2021_Final.pdf
|
https://clinicaltrials.gov/ct2/show/NCT04762680
|
|
10346
|
SCB-2019
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Protein subunit
|
Phase 3
|
Clover Biopharmaceuticals
|
NA
|
Australia
|
NA
|
NA
|
Intramuscular
|
NA
|
NA
|
Novel recombinant SARSCoV-2 Spike trimer fusion protein
|
NA
|
NA
|
Belgium, Brazil, Colombia, Dominican Republic, Germany, Nepal, Panama, Philippines, Poland
|
NA
|
NA
|
NCT04405908
|
https://extranet.who.int/pqweb/sites/default/files/documents/Status_of_COVID-19_Vaccines_within_WHO_EUL-PQ_evaluation_process-16June2021_Final.pdf
|
https://clinicaltrials.gov/ct2/show/NCT04405908
|
|
10347
|
COVIran Barekat
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Inactivated
|
Phase 3
|
Shifa Pharmed Industrial Co.
|
2021
|
Iran
|
18 - 75 years
|
2 doses 28 days apart
|
Intramuscular
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
BIV1-CovIran, COVIran Barkat
|
NA
|
NA
|
http://en.irct.ir/trial/54881
|
https://en.irct.ir/trial/52701
|
|
10348
|
GRAd-COV2
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Non-replicating viral vector
|
Phase 3
|
ReiThera Srl
|
NA
|
Italy
|
18 years and above
|
2 doses 21 days apart
|
Intramuscular
|
NA
|
Spike protein of SARS-CoV-2 virus
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
NCT04791423
|
https://clinicaltrials.gov/show/NCT04791423
|
NA
|
|
10349
|
Vidprevtyn
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Protein subunit
|
Phase 3
|
Sanofi Pasteur
|
2021
|
USA
|
18 years and above
|
2 doses 21 days apart
|
Intramuscular
|
AS03
|
SARS-CoV-2 protein
|
NA
|
US FDA
|
GlaxoSmithKline
|
NA
|
VAT00002, VAT00008
|
NA
|
NCT04762680
|
https://clinicaltrials.gov/show/NCT04762680
|
https://www.sanofi.com/en/our-covid-19-vaccine-candidates/phase-3-clinical-trial-for-COVID19-recombinant-protein-vaccine-candidate
|
|
10350
|
Skycovion
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Protein subunit
|
Phase 3
|
SK Bioscience Co. Ltd.
|
2021
|
South Korea
|
19 - 85 years
|
2 doses 28 days apart
|
Intramuscular
|
AS03
|
Recombinant SARS-CoV-2 protein
|
NA
|
NA
|
International Vaccine Institute, GlaxoSmithKline, Coalition for Epidemic Preparedness Innovations
|
NA
|
GBP510
|
NA
|
NCT04750343
|
https://clinicaltrials.gov/show/NCT04750343
|
NA
|
|
10351
|
QazVac
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Inactivated
|
Phase 3
|
Research Institute for Biological Safety Problems
|
2020
|
Kazakhstan
|
18 years and above
|
2 doses 21 days apart
|
Intramuscular
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
QazCovid-in
|
NA
|
NCT04691908
|
https://clinicaltrials.gov/show/NCT04691908
|
NA
|
|
10352
|
Covovax (Nuvaxovid)
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Protein subunit
|
Phase 3
|
Novavax Inc.
|
2020
|
Australia
|
18 - 59 years
|
2 doses 21 days apart
|
Intramuscular
|
NA
|
NA
|
NA
|
US FDA
|
NA
|
NA
|
TAK-019, SARS-CoV-2 rS
|
NA
|
NCT04368988
|
https://clinicaltrials.gov/show/NCT04368988
|
https://clinicaltrials.gov/ct2/show/NCT04368988
|
|
10353
|
COVIVAC
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Inactivated
|
Phase 3
|
Instituto Butantan
|
2020
|
Brazil
|
18 years and above
|
2 doses 2 weeks apart
|
Intramuscular
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
ADAPTCOV, NDV-HXP-S vaccine, , HXP-GPOVac, Patria, ButanVac
|
NA
|
NCT04456595
|
https://clinicaltrials.gov/show/NCT04456595
|
NA
|
|
10354
|
SCTV01C
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Subunit vaccine
|
Phase 3
|
Sinocelltech Ltd.
|
2021
|
China
|
18 years and above
|
2 doses 14 days apart
|
Intramuscular
|
NA
|
Spike protein of SARS-CoV-2 virus
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
NCT05043311
|
http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5890
|
NA
|
|
10355
|
CoviVac
|
COVID-19
|
Respiratory
|
SARS-CoV-2 virus
|
positive-sense, single-stranded RNA
|
Inactivated
|
Phase 3
|
Chumakov Centre at the Russian Academy of Sciences
|
2021
|
Russia
|
18 - 60 years
|
2 doses 14 days apart
|
Intramuscular
|
NA
|
Inactivated SARS-CoV-2 virus
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
https://www.precisionvaccinations.com/vaccines/covivac-russia-covid-19-vaccine
|
NA
|
|
10356
|
V70P5
|
Influenza (flu)
|
Respiratory
|
Influenza virus
|
positive-sense, single-stranded RNA
|
Inactivated
|
Phase 3
|
Novartis
|
2015
|
USA
|
6 months - 71 months
|
2 doses
|
Intramuscular
|
NA
|
Inactivated Influenza virus
|
NA
|
NA
|
NA
|
NA
|
NBP607
|
NA
|
NCT00644059
|
https://clinicaltrials.gov/ct2/show/NCT00644059?recrs=ade&cond=Influenza%2C+Human&phase=23&draw=2&rank=14
|
NA
|
|
10357
|
NBP607-QIV
|
Influenza (flu)
|
Respiratory
|
Influenza virus
|
positive-sense, single-stranded RNA
|
Inactivated
|
Phase 3
|
SK Chemicals Co. Ltd.
|
2015
|
South Korea
|
6 months - 18 years
|
1- 2 doses depending on volume and age
|
Intramuscular
|
NA
|
Inactivated Influenza virus
|
Cell culture based
|
NA
|
NA
|
NA
|
NA
|
NA
|
NCT02914275
|
https://clinicaltrials.gov/ct2/show/NCT02914275?recrs=ade&cond=Influenza%2C+Human&phase=23&draw=2&rank=18
|
NA
|
|
10358
|
Seqirus QIV
|
Influenza (flu)
|
Respiratory
|
Influenza virus
|
positive-sense, single-stranded RNA
|
Inactivated
|
Phase 3
|
Seqirus
|
2019
|
USA
|
6 months - 59 months
|
1- 2 doses depending on volume and age
|
Intramuscular
|
NA
|
Four recommended influenza strains for the Northern Hemisphere 2016/2017 influenza season
|
NA
|
US FDA
|
NA
|
NA
|
NA
|
NA
|
NCT02914275
|
https://www.clinicaltrials.gov/ct2/show/NCT02914275
|
NA
|
|
10359
|
RSV F vaccine
|
Respiratory syncytial virus infection
|
Respiratory
|
Respiratory syncytial virus
|
negative-sense, single-stranded RNA
|
Live-attenuated
|
Phase 3
|
Novavax Inc.
|
2020
|
USA
|
18 - 40 years
|
2 doses 9 months apart
|
Intramuscular
|
Aluminum
|
RSV surface glycoprotein
|
NA
|
NA
|
Bill and Melinda Gates Foundation
|
NA
|
NA
|
NA
|
NCT02624947
|
https://clinicaltrials.gov/ct2/show/NCT02624947?recrs=bde&cond=Respiratory+Syncytial+Virus+%28RSV%29&phase=23&draw=2&rank=2
|
NA
|
|
10360
|
Motavizumab
|
Respiratory syncytial virus infection
|
Respiratory
|
Respiratory syncytial virus
|
negative-sense, single-stranded RNA
|
Protein subunit
|
Phase 3
|
MedImmune LLC
|
2013
|
USA
|
upto 1 year
|
5 doses in interval for 1 month
|
Intramuscular
|
NA
|
Fusion glycoprotein of RSV
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
NCT00129766
|
https://clinicaltrials.gov/ct2/show/NCT00129766?recrs=bde&cond=Respiratory+Syncytial+Virus+%28RSV%29&phase=23&draw=2&rank=3
|
NA
|
|
10361
|
Ad26. RSV. preF
|
Respiratory syncytial virus infection
|
Respiratory
|
Respiratory syncytial virus
|
negative-sense, single-stranded RNA
|
Recombinant viral vector
|
Phase 3
|
Janssen Pharmaceutical
|
2021
|
USA
|
18 - 59 years
|
2 doses 6 months apart
|
Intramuscular
|
NA
|
Fusion glycoprotein of RSV
|
NA
|
US FDA
|
NA
|
NA
|
NA
|
NA
|
NCT05070546
|
https://clinicaltrials.gov/ct2/show/NCT05070546?recrs=bde&cond=Respiratory+Syncytial+Virus+%28RSV%29&phase=23&draw=2&rank=8
|
https://www.fda.gov/media/105619/download
|
|
10362
|
MK-1654
|
Respiratory syncytial virus infection
|
Respiratory
|
Respiratory syncytial virus
|
negative-sense, single-stranded RNA
|
NA
|
Phase 3
|
Merck & Co. Inc.
|
2021
|
USA
|
upto 1 year
|
NA
|
Intramuscular
|
NA
|
Fusion glycoprotein of RSV
|
NA
|
US FDA
|
NA
|
NA
|
NA
|
NA
|
NCT04938830
|
https://clinicaltrials.gov/ct2/show/NCT04938830?recrs=bde&cond=Respiratory+Syncytial+Virus+%28RSV%29&phase=23&draw=2&rank=12
|
https://ichgcp.net/clinical-trials-registry/NCT04938830
|
|
10363
|
STAMARiL
|
Yellow fever
|
Hemorrhagic
|
Yellow fever virus
|
positive-sense, single-stranded RNA
|
Live-attenuated
|
Phase 3
|
Sanofi Pasteur
|
NA
|
France
|
10 months
|
Single dose
|
Subcutaneous
|
NA
|
17D-204 strain of yellow fever virus
|
Produced in specified pathogen-free chick embryos
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
https://www.sanofipasteur.co.uk/-/media/ems/conditions/vaccines/brands/oneportal-ie/pdf/105_stamaril_mah_address_update_12_2017_uk.pdf
|
NA
|
|
10364
|
TAK-003
|
Dengue fever
|
Hemorrhagic
|
Dengue virus
|
positive-sense, single-stranded RNA
|
Live-attenuated
|
Phase 3
|
Takeda Pharmaceutical Company Limited
|
NA
|
USA
|
4 - 16 years
|
NA
|
Subcutaneous
|
NA
|
Dengue virus serotypes (1, 2, 3 and 4)
|
Mammalian cell vero culture
|
NA
|
NA
|
NA
|
TDV
|
30684747
|
NA
|
https://www.sciencedirect.com/science/article/pii/S1201971219300402
|
NA
|
|
10365
|
TV-003/005
|
Dengue fever
|
Hemorrhagic
|
Dengue virus
|
positive-sense, single-stranded RNA
|
Live-attenuated
|
Phase 3
|
Merck & Co. Inc.
|
NA
|
Brazil
|
2 - 59 years
|
NA
|
Subcutaneous
|
NA
|
Dengue virus serotypes (1, 2, 3 and 4)
|
Mammalian cell vero culture
|
NA
|
National Institute of Allergy and Infectious Diseases
|
NA
|
TetraVax-DV
|
30684747
|
NCT02406729
|
https://www.sciencedirect.com/science/article/pii/S1201971219300402
|
https://clinicaltrials.gov/ct2/show/NCT02406729
|
|
10366
|
EPAXAL
|
Hepatitis A
|
Hepatitic
|
Hepatitis A virus
|
positive-sense, single-stranded RNA
|
Inactivated
|
Phase 3
|
Crucell, Berna Biotech
|
NA
|
Berne, Switzerland
|
NA
|
P: 24 U; Adults: 24 U
|
Intramuscular
|
NA
|
RG-SB
|
NA
|
NA
|
NA
|
NA
|
NA
|
29661808
|
NA
|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360863/
|
NA
|
|
10367
|
Aimugen
|
Hepatitis A
|
Hepatitic
|
Hepatitis A virus
|
positive-sense, single-stranded RNA
|
Inactivated
|
Phase 3
|
Chemo-Sero-Therapeutic Research Institute
|
NA
|
Japan
|
NA
|
P: 0.5 µg; Adults: 0.5 µg
|
Intramuscular
|
Aluminum (aluminium hydroxide)
|
KRM003
|
NA
|
NA
|
NA
|
NA
|
NA
|
29661808
|
NA
|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360863/
|
NA
|
|
10368
|
Hepatyrix
|
Hepatitis A, Typhoid
|
Hepatitic
|
Hepatitis A virus, Salmonella typhi
|
double stranded DNA
|
Inactivated
|
Phase 3
|
Sanofi Pasteur
|
2015
|
Belgium
|
15 years and above
|
Single dose
|
Intramuscular
|
NA
|
Hepatitis A viral protein along with Vi polysaccharide antigen (a part of the Salmonella typhi (Ty2 strain) bacterium
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
https://www.hpra.ie/img/uploaded/vaccines/PIL_PA1077099001.pdf
|
NA
|
|
10369
|
SYN023 (Freeze-dried Rabies Vaccine for Human Use (Vero Cells))
|
Rabies
|
Neurologic
|
Rabies virus
|
negative-sense, single-stranded RNA
|
NA
|
Phase 3
|
Synermore Biologics (Suzhou) Co. Ltd.
|
2020
|
China
|
18 years and above
|
5 doses on day 1, 4, 8, 15 and 29
|
Intramuscular
|
NA
|
NA
|
NA
|
US FDA
|
Simoon Record Pharma Information Consulting Co. Ltd., Clinchoice Inc.
|
NA
|
NA
|
NA
|
NCT04644484
|
https://clinicaltrials.gov/ct2/show/NCT04644484?cond=Rabies+Human&phase=23&draw=2&rank=4
|
NA
|
|
10370
|
JE-VAX
|
Viral encephalitis
|
Neurologic
|
West Nile virus
|
positive-sense, single-stranded RNA
|
Live-attenuated
|
Phase 3
|
Research Foundation for Microbial Diseases of Osaka University
|
NA
|
China
|
NA
|
NA
|
Subcutaneous
|
NA
|
Nakayama-NIH/Beijing-1(P1) strain
|
Mouse brain based
|
NA
|
NA
|
Asia
|
SA 14-14-2 vaccine
|
24161909
|
NA
|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185882/
|
NA
|
|
10371
|
Simplirix
|
Genital Herpes
|
Cutaneous
|
Herpes simplex virus
|
double stranded DNA
|
Subunit vaccine
|
Phase 3
|
GlaxoSmithKline
|
2008
|
UK
|
18 - 30 years
|
NA
|
Intraperitoneal
|
3-deacylated form of MPL, alum
|
Herpes simplex virus 2 glycoprotein D (gD-2)
|
NA
|
NA
|
National Institute of Allergy and Infectious Diseases
|
NA
|
NA
|
NA
|
NCT00057330
|
https://www.precisionvaccinations.com/vaccines/herpes-vaccine-candidates, https://clinicaltrials.gov/ct2/show/NCT00057330
|
NA
|
|
10372
|
Sf21-VLP (PXVX0317)
|
Chikungunya fever
|
Exanthous
|
Chikungunya virus
|
positive-sense, single-stranded RNA
|
Virus like particle
|
Phase 3
|
Emergent BioSolutions
|
2021
|
NA
|
12 - 65 years
|
NA
|
NA
|
Alhydrogel
|
NA
|
Virus-like particle made using baculovirus and Sf21 insect cells
|
US FDA
|
NA
|
NA
|
NA
|
NA
|
NCT05072080
|
https://link.springer.com/chapter/10.1007/82_2019_175
|
https://clinicaltrials.gov/ct2/show/NCT05072080
|
|
10373
|
PENN CHIKV-2008 (PC-08)
|
Chikungunya fever
|
Exanthous
|
Chikungunya virus
|
positive-sense, single-stranded RNA
|
DNA based vaccine
|
Phase 3
|
University of Pennsylvania
|
2011
|
USA
|
NA
|
NA
|
NA
|
NA
|
CHIKV envelope proteins (E1, E2, and E3)
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0006919
|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019110/
|
|
10374
|
MRVAC
|
Measles, Rubella
|
Exanthous
|
Morbillivirus, Rubella virus
|
negative-sense, single-stranded RNA
|
Live-attenuated
|
Phase 3
|
Center for Research and Production of Vaccines and Biologicals
|
2018
|
Vietnam
|
1 - 45 years
|
NA
|
Subcutaneous
|
NA
|
Strain AIK-C measles virus clone with Takahashi rubella virus
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
NCT03713359
|
https://clinicaltrials.gov/ct2/show/NCT03713359?recrs=abde&cond=measles+vaccines&phase=123&draw=2&rank=54
|
NA
|