| ID |
Reference |
Source Clone name |
Sequence |
Motif |
Target-tumor |
Target-cell |
Receptors-biomarker |
Phage/Library |
In vitro/Ex-vivo |
In vivo |
Homing/targeting |
Payloads |
patent |
| 1001 | He X et al. Mol Pharm. 2011 Apr 4;8(2):430-8. | 4R22 | CSNIDARAC | NA | Lung (major), Colon, Breast cancer | Tumor cell | NA | T7 phage / CX7C peptide library | H460, A549 cells, H226 cells, SNU484, MDA-MB-231, HT29 cells, H460 Cell | BALB/ C mice with lung tumor | Homing | Liposomal doxorubicin | US2010/0233161A1 |
| 1002 | He X et al. Mol Pharm. 2011 Apr 4;8(2):430-8. | 3R5 | CDPSRGKNC | NA | Lung (major), Colon, Breast cancer | Tumor cell | NA | T7 phage / CX7C peptide library | H460, A549 cells, H226 cells, SNU484, MDA-MB-231, HT29 cells | NA | Targeting | NA | US2010/0233161A1 |
| 1003 | He X et al. Mol Pharm. 2011 Apr 4;8(2):430-8. | 4R24 | CPSDLKDAC | NA | Lung (major), Colon, Breast cancer | Tumor cell | NA | T7 phage / CX7C peptide library | H460, A549 cells, H226 cells, SNU484, MDA-MB-231, HT29 cells | NA | Targeting | NA | US2010/0233161A1 |
| 1004 | He X et al. Mol Pharm. 2011 Apr 4;8(2):430-8. | 4R4 | CRTTRGTKC | NA | Lung (major), Colon, Breast cancer | Tumor cell | NA | T7 phage / CX7C peptide library | H460, A549 cells, H226 cells, SNU484, MDA-MB-231, HT29 cells | NA | Targeting | NA | US2010/0233161A1 |
| 1005 | He X et al. Mol Pharm. 2011 Apr 4;8(2):430-8. | 4R8 | CRMTRNKPC | NA | Lung (major), Colon, Breast cancer | Tumor cell | NA | T7 phage / CX7C peptide library | H460, A549 cells, H226 cells, SNU484, MDA-MB-231, HT29 cells | NA | Targeting | NA | US2010/0233161A1 |
| 1006 | He X et al. Mol Pharm. 2011 Apr 4;8(2):430-8. | 4R17 | CRVSRQNKC | NA | Lung (major), Colon, Breast cancer | Tumor cell | NA | T7 phage / CX7C peptide library | H460, A549 cells, H226 cells, SNU484, MDA-MB-231, HT29 cells | NA | Targeting | NA | US2010/0233161A1 |
| 1007 | He X et al. Mol Pharm. 2011 Apr 4;8(2):430-8. | 4R9 | CAKIDPELC | NA | Lung (major), Colon, Breast cancer | Tumor cell | NA | T7 phage / CX7C peptide library | H460, A549 cells, H226 cells, SNU484, MDA-MB-231, HT29 cells | NA | Targeting | NA | US2010/0233161A1 |
| 1008 | He X et al. Mol Pharm. 2011 Apr 4;8(2):430-8. | 3R14 | CGGERGKSC | NA | Lung (major), Colon, Breast cancer | Tumor cell | NA | T7 phage / CX7C peptide library | H460, A549 cells, H226 cells, SNU484, MDA-MB-231, HT29 cells | NA | Targeting | NA | US2010/0233161A1 |
| 1017 | Liu S et al. Acta Pharmacol Sin. 2011 Jan;32(1):79-88. | Bombesin | QRLGNQWAVGHLM | NA | Lung, gastric cancer, Neuroblastoma | NA | NA | NA | MCF-7, DU145, A375 HeLa, A875, M14, A549, ZR-75-30, Raji, NB4, K562 cell lines | Eight-week-old female nude mice with MCF-7 xenograft | Homing | MG2 peptide | NA |
| 1020 | Veleva AN et al. Molecules. 2011 Jan 21;16(1):900-14. | L12 | QFPPKLTNNSML | NA | Lung carcinoma | NA | NA | M13 phage /12mer peptide library | Human blood outgrowth endothelial cells (HBOEC) | Lewis lung carcinoma (LLC) tumor-bearing mice | Homing | Cu-DOTA radionuclide | NA |
| 1021 | Veleva AN et al. Molecules. 2011 Jan 21;16(1):900-14. | L25 | SYDILKPNPQRL | NA | Lung carcinoma | NA | NA | M13 phage /12mer peptide library | Human blood outgrowth endothelial cells (HBOEC) | Lewis lung carcinoma (LLC) tumor-bearing mice | Homing | NA | NA |
| 1022 | Veleva AN et al. Molecules. 2011 Jan 21;16(1):900-14. | L34 | SHGKPPSFSPYT | NA | Lung carcinoma | NA | NA | M13 phage /12mer peptide library | Human blood outgrowth endothelial cells (HBOEC) | Lewis lung carcinoma (LLC) tumor-bearing mice | Homing | NA | NA |
| 1027 | Niu G et al. J Nucl Med. 2010 Nov;51(11):1659-62. | NA | CLSYYPSYC | NA | Lung cancer | NA | NA | M13 phage /9- mer peptide library | NA | Tumor-bearing nude mice (H460-cell xenograft model) | Homing | FITC, camptothecin | NA |
| 1031 | Whitney M et al. J Biol Chem. 2010 Jul 16;285(29):22532-41. | NA | RLQLKL | NA | Lung metastassis | NA | NA | M13 phage/Met-His6-E9-X6-R9 peptide library | NA | PyMTmice with spontaneous progressive mammary tumors or nude mice with MDA-MB-435 clone M4A4 ( xenograft tumors). | Homing | Cy5 | NA |
| 1171 | Kawasaki M et al. J Biol Chem. 2003 Dec 5;278(49):49301-7. | P-5m GHGKHKNK | GHGKHKNK | HGK | Lung metastassis | NA | Vitronectin | NA | MDA-MB-231 cells | Mice bearing malignant melanoma cell line B16-F10 derived tumor | Homing | NA | NA |
| 1351 | Chang DK et al. PLoS One. 2009;4(1):e4171. | PC5-2 | TDSILRSYDWTY | WTYY | Lung cancer, non-small cell lung cancer (NSCLC) | NA | NA | M15 phage /random peptide library | CL1-5, PC13, Specimens of pulmonary adenocarcinoma | SCID mice bearing CL1-5-derived tumors | Homing | FITC, doxorubicin or vinorelbine | US 2008/0193375A1 |
| 1352 | Chang DK et al. PLoS One. 2009;4(1):e4171. | PC5- 4 | DMPKQLLAPWYY | WTYY | Lung cancer, non-small cell lung cancer (NSCLC) | NA | NA | M15 phage /random peptide library | CL1-5, PC13, Specimens of pulmonary adenocarcinoma | NA | Targeting | NA | US 2008/0193375A1 |
| 1353 | Chang DK et al. PLoS One. 2009;4(1):e4171. | PC4-5 | DMPKQLLAPWYY | WTYY | Lung cancer, non-small cell lung cancer (NSCLC) | NA | NA | M15 phage /random peptide library | CL1-5, PC13, Specimens of pulmonary adenocarcinoma | NA | Targeting | NA | US 2008/0193375A1 |
| 1354 | Chang DK et al. PLoS One. 2009;4(1):e4171. | PC4-9 | SYPLSFLGPLIS | WTYY | Lung cancer, non-small cell lung cancer (NSCLC) | NA | NA | M15 phage /random peptide library | CL1-5, PC13, Specimens of pulmonary adenocarcinoma | NA | Targeting | NA | US 2008/0193375A1 |
| 1355 | Chang DK et al. PLoS One. 2009;4(1):e4171. | PC3-2 | TQQPLEGHQLPY | WTYY | Lung cancer, non-small cell lung cancer (NSCLC) | NA | NA | M15 phage /random peptide library | CL1-5, PC13, Specimens of pulmonary adenocarcinoma | NA | Targeting | NA | US 2008/0193375A1 |
| 1356 | Chang DK et al. PLoS One. 2009;4(1):e4171. | PC3-3 | TGVSWSVAQPSF | WTYY | Lung cancer, non-small cell lung cancer (NSCLC) | NA | NA | M15 phage /random peptide library | CL1-5, PC13, Specimens of pulmonary adenocarcinoma | NA | Targeting | NA | US 2008/0193375A1 |
| 1357 | Chang DK et al. PLoS One. 2009;4(1):e4171. | PC3-4 | SVSVGMKPSPRP | WTYY | Lung cancer, non-small cell lung cancer (NSCLC) | NA | NA | M15 phage /random peptide library | CL1-5, PC13, Specimens of pulmonary adenocarcinoma | NA | Targeting | NA | US 2008/0193375A1 |
| 1358 | Chang DK et al. PLoS One. 2009;4(1):e4171. | PC3-5 | SQWNSPPSSAAF | WTYY | Lung cancer, non-small cell lung cancer (NSCLC) | NA | NA | M15 phage /random peptide library | CL1-5, PC13, Specimens of pulmonary adenocarcinoma | NA | Targeting | NA | US 2008/0193375A1 |
| 1373 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | PC5-52 | SVSVGMKPSPRP | PSP | Lung and Prostate cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice human cancers including human lung (H460), colon (HCT116), breast (BT483), prostate (PC3), liver (Mahlavu), and pancreatic (PaCa) cancer xenografts | Homing | Doxorubicin | US/ 20100119444A1,US 2010/0260673A1 |
| 1374 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | PC5-54 | WPLHTSVYPPSP | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing | NA | US 2008/0193510A1 |
| 1375 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-5 | NTLPPFSPPSPP | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | US 2008/0193510A1 |
| 1376 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-10 | SFPDSNIAPSSP | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | US 2008/0193510A1 |
| 1377 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-8 | QHAPSNSKSVLT | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | US 2008/0193510A1 |
| 1378 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-7 | WPTYLNPSSLKA | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | NA |
| 1379 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-57 | GPSGNLHIRPAS | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | NA |
| 1380 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-53 | SPLLSTRAVQLS | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | US 2008/0193510A1 |
| 1381 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-58 | SPMFTMIQGDAQ | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | US 2008/0193510A1 |
| 1382 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-60 | VNSHQALWSPAQ | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | NA |
| 1383 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-4 | STLPPPLRFANV | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | US 2008/0193510A1 |
| 1384 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-2 | SFNQPYLYKTAF | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | NA |
| 1385 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-3 | YHTRIALPDNLP | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | NA |
| 1386 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-11 | AQSTAFQKPLLM | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | NA |
| 1474 | Funovics M et al. Neoplasia. 2005 Oct;7(10):904-11. | NA | BCDSDSDITWDQLWDLMK | NA | Human prostrate cancer, lewis lung carcinoma | Tumor cell,endothelial cell | E-selectin | NA | Activated HUVEC, Human prostrate biopsies,llc cell line | Mouse xenograft model of LLC | Homing | FITC , nanoparticle CLIO(Cy5.5) | NA |
| 1752 | Hatakeyama S et al. Proc Natl Acad Sci U S A.2011 Dec 6;108(49):19587-92. | IF7 | IFLLWQR | NA | Lung carcinoma, Prostate cancer, Breast Cancer, Colon cancer | Tumor vessel | Anxa1 | NA | NA | Nude mice bearing HCT116 tumors,C57BL6 mice bearing B16F1 and Lewis lung carcinoma,SCID mice bearing prostate tumor | Homing | Alexa 488 (A488), Drug SN-38 , 17-AAG (GA), a geldanamycin analogue | US 7,470,658 B2 |