|
| Primary information |
|---|
| ID | 16220 |
| Therapeutic ID | Th1733 |
| Protein Name | HGTV-43 |
| Sequence | NA
|
| Molecular Weight | NA |
| Chemical Formula | NA |
| Isoelectric Point | NA |
| Hydrophobicity | NA |
| Melting point | NA |
| Half-life | NA |
| Description | HGTV43 is an anti-sense treatment designed to produce T cells that are genetically resistant to HIV infection. HGTV43 is one of a number of so-called 'gene transfer vectors' developed by the biotechnology company Enzo Biochem, Inc. |
| Indication/Disease | Investigated for use/treatment in HIV infection. |
| Pharmacodynamics | NA |
| Mechanism of Action | HGTV43 works by 'turning off' the genes which HIV needs to grow and reproduce in human cells. Engineered genes are inserted directly into cells to regulate the function of the genes essential for HIV replication. These genetically modified CD4 cells are then transferred back to the individual. The theory is that these individuals will thus have a pool of fully functioning CD4 cells immune to HIV infection. |
| Toxicity | NA |
| Metabolism | NA |
| Absorption | NA |
| NA |
| Clearance | NA |
| Categories | NA |
| Patents Number | NA |
| Date of Issue | NA |
| Date of Expiry | NA |
| Drug Interaction | NA |
| Target | NA |
| Brand Name | NA |
| Company | NA |
| Brand Description | NA |
| Prescribed For | NA |
| Chemical Name | NA |
| Formulation | NA |
| Physical Appearance | NA |
| Route of Administration | NA |
| Recommended Dosage | NA |
| Contraindication | NA |
| Side Effects | NA |
| Useful Link 1 | Link |
| Useful Link 2 | NA |
| Remarks | NA |