|
| Primary information |
|---|
| ID | 10875 |
| Therapeutic ID | Th1235 |
| Protein Name | Protein S human |
| Sequence | >Th1235_Protein_S_human
MRVLGGRCGALLACLLLVLPVSEANFLSKQQASQVLVRKRRANSLLEETKQGNLERECIEELCNKEEAREVFENDPETDYFYPKYLVCLRSFQTGLFTAARQSTNAYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLNLDTKYELLYLAEQFAGVVLYLKFRLPEISRFSAEFDFRTYDSEGVILYAESIDHSAWLLIALRGGKIEVQLKNEHTSKITTGGDVINNGLWNMVSVEELEHSISIKIAKEAVMDINKPGPLFKPENGLLETKVYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVEKGSYYPGSGIAQFHIDYNNVSSAEGWHVNVTLNIRPSTGTGVMLALVSGNNTVPFAVSLVDSTSEKSQDILLSVENTVIYRIQALSLCSDQQSHLEFRVNRNNLELSTPLKIETISHEDLQRQLAVLDKAMKAKVATYLGGLPDVPFSATPVNAFYNGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVWKKTKNS
|
| Molecular Weight | 75123 |
| Chemical Formula | NA |
| Isoelectric Point | 5.0-5.5 (7 |
| Hydrophobicity | NA |
| Melting point | NA |
| Half-life | NA |
| Description | Protein S (also known as S-Protein) is a vitamin K-dependent plasma glycoprotein synthesized in the liver. In the circulation, Protein S exists in two forms: a free form and a complex form bound to complement protein C4b-binding protein (C4BP). In humans, protein S is encoded by the PROS1 gene. |
| Indication/Disease | To prevent coagulation and stimulating fibrinolysis |
| Pharmacodynamics | NA |
| Mechanism of Action | Cofactor for activated protein C |
| Toxicity | NA |
| Metabolism | NA |
| Absorption | NA |
| NA |
| Clearance | NA |
| Categories | Amino Acids, Peptides, and Proteins,Anticoagulants,Biological Factors,Blood Coagulation Factor Inhibitors,Blood Coagulation Factors,Blood Proteins,Carbohydrates,Glycoconjugates,Glycoproteins,Hematologic Agents,Proteins |
| Patents Number | NA |
| Date of Issue | NA |
| Date of Expiry | NA |
| Drug Interaction | NA |
| Target | Coagulation factor V,Coagulation factor X,Vitamin K-dependent protein C |
| Brand Name | Protein S human |
| Company | NA |
| Brand Description | NA |
| Prescribed For | In the coagulation system, protein S functions as an anticoagulant cofactor protein |
| Chemical Name | NA |
| Formulation | Purified protein S is supplied in 50% (vol/vol) glycerol/H2O |
| Physical Appearance | Solid |
| Route of Administration | NA |
| Recommended Dosage | NA |
| Contraindication | NA |
| Side Effects | NA |
| Useful Link 1 | Link |
| Useful Link 2 | NA |
| Remarks | NA |