Detailed description page of ThPDB2
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16102 details |
| Primary information | |
|---|---|
| ID | 16102 |
| Therapeutic ID | Th1678 |
| Protein Name | Tyrosinase |
| Sequence | >Th1678_Tyrosinase MESTTVLLAASTLLLVLHASYGQFPRACSTAQVLLSKECCPVWPGDNSSCGEVSGRGVCQDVVPSNSPVGAQFPFSGIDDRENWPIVFYNRTCQCQGNFMGYNCGECRFGYTGPNCTVRRNMIRKEIFRMTTAEKDKFIAYLNLAKRTISQDYVISTGTYEQMNNGSNPMFADINVYDLFVWLHYYASRDAFLEDGSVWANIDFAHEAPGFPPWHRFFLLLWEREIQKVAADDNFTIPFWDWRDAQQCDLCTDEFFGGTHPTSNNLLSPASFFSSWQVICSQPEEYNRLRIICNGTNEGPLLRSPGRHDRNRTPRLPTSADVEACLSLTDYETGAMDRFANFSFRNTLEGYAVPASGIANRSQSNMHNSLHVFMNGSMSNVQGSANDPIFVLHHAFVDSLFEQWLRRHQPSLDVYPEANAPVGHNREYNMVPFIPLFTNGEFFVQSRDLGYDYDYLAESGSIEDFLLPYLEQARQIWQWLLGAAVVGGLVTAVIATIISLTCRRKRRTKTSEETRPLLMEAEDYHATYQSNL |
| Molecular Weight | NA |
| Chemical Formula | NA |
| Isoelectric Point | NA |
| Hydrophobicity | NA |
| Melting point | NA |
| Half-life | NA |
| Description | Tyrosinase is a multi-copper-containing multifunctional metalloenzyme with 4 possible oxidation states.[A231829, A231834, A231839] It is responsible for producing melanin pigment across the phylogenetic spectrum.[A231829, A231834, A231839] Within mammals, tyrosinase is found specifically in melanocytes in a glycosylated form and plays a critical role in regulating the process of melanin biosynthesis (also known as melanogenesis).[A231829, A231839] It is recognized as being the main enzyme responsible for enzymatic browning and melanogenesis in mammals, thus causing undesired browning of fruits and vegetables and diseases resulting from melanin overproduction.[A231829] |
| Indication/Disease | NA |
| Pharmacodynamics | NA |
| Mechanism of Action | During melanogenesis, tyrosinase acts as a rate-limiting enzyme.[A231829] |
| Toxicity | NA |
| Metabolism | NA |
| Absorption | NA |
| NA | |
| Clearance | NA |
| Categories | Enzymes |
| Patents Number | NA |
| Date of Issue | NA |
| Date of Expiry | NA |
| Drug Interaction | NA |
| Target | NA |
| Brand Name | NA |
| Company | NA |
| Brand Description | NA |
| Prescribed For | NA |
| Chemical Name | NA |
| Formulation | NA |
| Physical Appearance | NA |
| Route of Administration | NA |
| Recommended Dosage | NA |
| Contraindication | NA |
| Side Effects | NA |
| Useful Link 1 | Link |
| Useful Link 2 | NA |
| Remarks | NA |