A database of FDA approved therapeutic peptides and proteins
ID | ThPPID | Name | Peptide Sequence | Length | Functional Classification | Disease | Brand | Company | Physical Appearance | Route of Administartion | Category | Target |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1537 | Th1116 | Canakinumab | H-GAMMA-1 (VH(1-118) Full view | 842 | IIIb | Immunological | ILARIS | Novartis Pharmaceuticals | White, preservative-free, lyophilized powder | Subcutaneous injection | Anti-Inflammatory Agents and Monoclonal antibodies | Interleukin-1 beta |
1548 | Th1117 | Ipilimumab | Heavy chain: QVQLVES Full view | 663 | IIIc | Cancer | YERVOY | Bristol-Myers Squibb | Sterile, preservative-free, clear to slightly opalescent, colorless to pale-yellow solution | N.A. | Antineoplastic Agents and Monoclonal antibodies | Cytotoxic T-lymphocyte protein 4 |
1560 | Th1121 | Pertuzumab | light chain DIQMTQSP Full view | 664 | IIIc | Cancer | Perjeta | Genentech | Sterile, clear to slightly opalescent, colorless to pale brown liquid | Intravenous infusion | Monoclonal antibodies | Receptor tyrosine-protein kinase erbB-2 |
1570 | Th1123 | Denosumab | Heavy chain EVQLLESG Full view | 664 | IIIc | Osteological | Xgeva | Amgen. | Sterile, preservative-free, clear, colorless to pale yellow solution | N.A. | Bone Density Conservation Agents and Monoclonal antibodies | Tumor necrosis factor ligand superfamily member 11 |
1571 | Th1123 | Denosumab | Heavy chain EVQLLESG Full view | 664 | IIIc | Osteological | Prolia | Amgen. | Sterile, preservative-free, clear, colorless to pale yellow solution | N.A. | Bone Density Conservation Agents and Monoclonal antibodies | Tumor necrosis factor ligand superfamily member 11 |
1583 | Th1125 | Golimumab | N.A. Full view | 0 | IIb | Immunological | Simponi Injection | N.A. | Clear to slightly opalescent, colorless to light yellow solution | Subcutaneous injection | Antipsoriatic Agents and Monoclonal antibodies and TNF inhibitor | Tumor necrosis factor |
1584 | Th1125 | Golimumab | N.A. Full view | 0 | IIb | Immunological | Simponi Injection | N.A. | Sterile concentrated solution of the golimumab antibody | Intravenous infusion | Antipsoriatic Agents and Monoclonal antibodies and TNF inhibitor | Tumor necrosis factor |
1609 | Th1132 | Belimumab | N.A. Full view | 0 | IIa | Immunological | Benlysta | GlaxoSmithKline | Sterile, white to off-white, preservative-free, lyophilized powder | Intravenous infusion | Monoclonal antibodies | Tumor necrosis factor ligand superfamily member 13B |
1627 | Th1138 | Raxibacumab | N.A. Full view | 0 | IIa | Immunological/Infectious | RAXIBACUMAB | GSK | Sterile, liquid formulation in single-dose vials | N.A. | Anti-Infective Agents and Monoclonal antibodies | Protective antigen |
1708 | Th1170 | Blinatumomab | DIQLTQSPASLAVSLGQRAT Full view | 504 | IIIc | Cancer/Genetic | Blincyto | AMGEN | Lyophilized Powder for intravenous administration | Intravenous | Antineoplastic Agents, Immunosuppressive Agents, Monoclonal antibodies, Antineoplastic and Immunomodulating Agents | B-lymphocyte antigen CD19; T-cell surface glycoprotein CD3 delta chain |
1828 | Th1218 | Anti-thymocyte Globulin (Equine) | NA Full view | 0 | IIIb | Immunological Disorders | ATGAM | NA | Solid | Intravenous | Antibody | NA |
1829 | Th1219 | Anti-thymocyte Globulin (Rabbit) | NA Full view | 0 | IIIb | Immunological Disorders | ATG-Fresenius | Genzyme Inc. | Concentrate for solution for infusion. | Intravenous | Antibody | T-cell surface glycoprotein CD1a, Major histocompatibility complex class I-related gene protein, Integrin alpha-L, T-lymphocyte activation antigen CD86, Low affinity immunoglobulin gamma Fc region receptor II-b, T-cell surface glycoprotein CD4, Integrin beta-1, Integrin alpha-V, Integrin beta-3 |
1837 | Th1226 | Dinutuximab | NA Full view | 0 | IIIc | Cancer | unituxin | NA | sterile, preservative-free, clear/colorless to slightly opalescent solution | Intravenous | Antibody, Immunosuppresive agent, Antineoplastic agent | Ganglioside GD2 (small molecule) |
1842 | Th1230 | Human Varicella-Zoster Immune Globulin | NA Full view | 0 | IIIa | Infectious Disease | VARIZIG | NA | lyophilized powder for solution | Intramuscular | Antibody | varicella zoster virus |
1843 | Th1231 | Ibritumomab tiuxetan | Heavy chain: QAYLQQS Full view | 652 | IIIc | Cancer | Zevalin | Spectrum Pharmaceuticals B.V. | Colourless Solution | Intravenous | Antibody, Immunosuppressive Agents | B-lymphocyte antigen CD20, Low affinity immunoglobulin gamma Fc region receptor III-B, Complement C1r subcomponent, Complement C1q subcomponent subunit A, Complement C1q subcomponent subunit B, Complement C1q subcomponent subunit C, Low affinity immunoglobulin gamma Fc region receptor III-A, Complement C1s subcomponent, High affinity immunoglobulin gamma Fc receptor I, Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b, Low affinity immunoglobulin gamma Fc region receptor II-c |