Primary information |
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PRRID | PRRID_0091 |
Ligand Name | Uric acid |
Source | NA |
Sequence of ligand | C12=C(NC(=O)N1)NC(=O)NC2=O |
Length | NA |
Type | DAMPs |
Occurence | Natural |
Role of Ligand | Induce the synthesis of IL-1β, TNF-α and TGF-β by murine macrophages. |
Name of receptor | NLRP3 |
Type of receptor | NLR |
Source | Rat |
Localization | primary astrocytes |
Domain | NA |
Sequence of Receptor | D4A523.fasta |
Swiss prot ID | D4A523 |
Length Of Receptor | 1035 |
Function | protein ‚Üë, activation of NLRP3 inflammasome in PD models |
Assay used | NA |
PMID | 28801521 |
Year of Publication | 2017 |
Pubchem assay | NA |
Pdb | PRR_0091.pdb |
3-D Structure | PRR_0091 (View) or (Download) |