Detailed description page of PRRDB2.0

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PRRID_0087 details
Primary information
PRRIDPRRID_0087
Ligand NameUnmethylated CpG DNA
SourceBacteria
Sequence of ligandNA
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of Ligandact as immuno stimulants
Name of receptorTLR9
Type of receptorTLR
Source TRIF mutant (C57BL/6J-Ticam1Lps2) mice
Localizationbone marrow-derived macrophage (BMDM) culture
Domain Toll/IL-1R (TIR) domain
Sequence of ReceptorQ9NR96.fasta
Swiss prot IDQ9NR96
Length Of Receptor1032
Functioninduces pro-inflammatory cytokine response
Assay usedQuantitative Real Time PCR, Cell Viability Assays, Immunoblot and Immunoprecipitations
PMID24019532
Year of Publication2013
Pubchem assayNA
PdbPRR_0087.pdb
3-D StructurePRR_0087 (View) or (Download)