Detailed description page of PRRDB2.0

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PRRID_0071 details
Primary information
PRRIDPRRID_0071
Ligand Namepolyinosinic-polycytidylic acid [poly(I:C)]
SourceNA
Sequence of ligandC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of Ligandpoly I:C expressed significantly higher levels of IFN-a1 and IFN-c and Mx
Name of receptorTLR3
Type of receptorTLR
Source Atlantic salmon (Salmo salar)
Localizationmuscle, head kidney, liver, gut, heart, spleen and gill
DomainNA
Sequence of ReceptorM1ZMQ4.fasta
Swiss prot IDM1ZMQ4
Length Of Receptor913
Functionplay a role in antiviral response in salmon
Assay usedReal-time PCR
PMID24736205
Year of Publication2014
Pubchem assayNA
PdbPRR_0071.pdb
3-D StructurePRR_0071 (View) or (Download)