Primary information |
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PRRID | PRRID_0069 |
Ligand Name | polyinosinic-polycytidylic acid [poly(I:C)] |
Source | NA |
Sequence of ligand | C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O |
Length | NA |
Type | Nucleic Acid |
Occurence | Synthetic |
Role of Ligand | Immunostimulant |
Name of receptor | TLR3 |
Type of receptor | TLR |
Source | Zebrafish |
Localization | Plasma membrane |
Domain | extracellular (or intra- endosomal) ligand-binding domain with a leucine-rich repeat (LRR) motif and a cytoplasmic signaling Toll/Interleukin-1 (IL-1) receptor homology (TIR) domain |
Sequence of Receptor | B8JIL3.fasta |
Swiss prot ID | B8JIL3 |
Length Of Receptor | 903 |
Function | induce IFN expression |
Assay used | NA |
PMID | 27721456 |
Year of Publication | 2016 |
Pubchem assay | NA |
Pdb | PRR_0069.pdb |
3-D Structure | PRR_0069 (View) or (Download) |