| Primary information |
|---|
| PRRID | PRRID_0065 |
| Ligand Name | Flagellin |
| Source | Salmonella typhimurium(Bacteria) |
| Sequence of ligand | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR |
| Length | 495 |
| Type | Protein |
| Occurence | Natural |
| Role of Ligand | triggers immune responses |
| Name of receptor | TLR5 |
| Type of receptor | TLR |
| Source | Chicken |
| Localization | splenocytes |
| Domain | cell surface |
| Sequence of Receptor | Q5GR02.fasta |
| Swiss prot ID | Q5GR02 |
| Length Of Receptor | 862 |
| Function | TLR2 and TLR5 promote cellular activation and the production of cytokines including proinflammatory interleukin (IL)-6, as well as those cytokines that help to initiate and modulate the adaptive immune response, including IL-4, IL-12, and interferon (IFN)-c |
| Assay used | ELISA |
| PMID | 24797722 |
| Year of Publication | 2014 |
| Pubchem assay | NA |
| Pdb | PRR_0065.pdb |
| 3-D Structure | PRR_0065 (View) or (Download) |